Results 41 to 50 of about 4,963 (200)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

中部ベトナムにおける草の根レベルの佛教:清福村の事例を中心に [PDF]

open access: yes, 2010
VĂN HÓA - LỊCH SỬ HUẾ QUA GÓC NHÌN LÀNG XÃ PHỤ CẬN VÀ QUAN HỆ VỚI BÊN NGOÀI Session 3: Văn hoá - lịch sử Huế trong mối quan hệ với bên ngoài フエの文化と歴史:周辺集落と外部との関係からの視点より Session 3: Culture - history of Hue in relationship with the outside regions ...
Suenari Michio, 末成 道男
core   +1 more source

Strata of standardization: the Phong Nha dialect of Vietnamese (Quảng Bình Province) in historical perspective [PDF]

open access: yes, 2015
International audienceThe present research, based on first-hand data, is intended as a contribution to the study of the present-day diversity of lesser-described Vietnamese dialects, and of the range of evolutionary paths to which they testify.
Ferlus, Michel   +2 more
core   +4 more sources

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati   +10 more
wiley   +1 more source

Oxytocin Dynamics in the Body and Brain Regulated by the Receptor for Advanced Glycation End-Products, CD38, CD157, and Nicotinamide Riboside

open access: yesFrontiers in Neuroscience, 2022
Investigating the neurocircuit and synaptic sites of action of oxytocin (OT) in the brain is critical to the role of OT in social memory and behavior.
Haruhiro Higashida   +26 more
doaj   +1 more source

Analyzing Electronic Excitations and Exciton Binding Energies in Y6 Films

open access: yesAdvanced Functional Materials, EarlyView.
The Y6 molecule is used for increasing the efficiency of organic solar cells. The exciton binding energy is calculated for ensembles of Y6 molecules that are representative of the typically used films. The calculations show that the excitons typically spread out over many molecules.
Sahar Javaid Akram   +2 more
wiley   +1 more source

広南阮氏の首府とフエ文化と中部ベトナム文化形成過程 [PDF]

open access: yes, 2010
VĂN HÓA - LỊCH SỬ HUẾ QUA GÓC NHÌN LÀNG XÃ PHỤ CẬN VÀ QUAN HỆ VỚI BÊN NGOÀI Session 3: Văn hoá - lịch sử Huế trong mối quan hệ với bên ngoài フエの文化と歴史:周辺集落と外部との関係からの視点より Session 3: Culture - history of Hue in relationship with the outside regions ...
Phan Thanh Hai, Phan Thanh Hải
core   +1 more source

Thiết kế hệ thống phân loại trái ớt sau thu hoạch ứng dụng thị giác máy tính [PDF]

open access: yes
Hiện nay, công nghệ xử lý ảnh ngày càng được ứng dụng phổ biến, đa dạng ở các lĩnh vực, kể cả trong nông nghiệp và công nghệ sau thu hoạch. Việc dùng thị giác máy tính để phân loại tình trạng lỗi của trái ớt là một điển hình giúp chọn lọc sản phẩm sau ...
Lâm Hồ Ngọc Hãn   +6 more
core   +2 more sources

Liquid Crystalline Inverted Lipid Phases and Reverse Micelles in Drug Delivery: From Molecular Design to Therapeutic Potential

open access: yesAdvanced Functional Materials, EarlyView.
Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu   +3 more
wiley   +1 more source

Inducing Ferromagnetism by Structural Engineering in a Strongly Spin‐Orbit Coupled Oxide

open access: yesAdvanced Functional Materials, EarlyView.
ABSTRACT Magnetic materials with strong spin‐orbit coupling (SOC) are essential for the advancement of spin‐orbitronic devices, as they enable efficient spin‐charge conversion, complex magnetic structures, spin‐valley physics, topological phases and other exotic phenomena.
Ji Soo Lim   +19 more
wiley   +1 more source

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