Results 51 to 60 of about 3,186,450 (234)

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül, Neriman Sıla Koç, Berrak Itır Aylı   +2 more
wiley   +1 more source

Manifesto on small airway involvement and management in asthma and chronic obstructive pulmonary disease: an Interasma (Global Asthma Association - GAA) and World Allergy Organization (WAO) document endorsed by Allergic Rhinitis and its Impact on Asthma (ARIA) and Global Allergy and Asthma European Network (GA2LEN) [PDF]

, 2016
Evidence that enables us to identify, assess, and access the small airways in asthma and chronic obstructive pulmonary disease (COPD) has led INTERASMA (Global Asthma Association) and WAO to take a position on the role of the small airways in these ...
A. Cruz, A. Fink-Wagner, A. Yanez, A. Yorgancioglu, ARIA, C. Baez Loyola, C. Nunes, D. Deleanu, D. Ryan, E. Hossny, F. Braido, F. Lavorini, F. Levi-Schaffer, for Interasma Executive Board, G. Passalacqua, G. Rodrigo, G. Walter Canonica, GA2LEN, H. Saito, I. J. Ansotegui, J. A. Ortega-Martell, J. Berstein, J. Bousquet, J. C. Ivancevich, J. Celedon, K. Dobashi, K. Ohta, L. Caraballo, L. Dubuske, L. J. Rosenwasser, L. P. Boulet, L. Zhang, M. Akdis, M. Ebisawa, M. Sanchez-Borges, M. Tang, M. Zernotti, N. Scichilone, O. S. Usmani, P. Greenberger, P. Vichyanond, R. Mosges, R. Pawankar, S. Benjaponpitak, S. Bonini, S. Fineman, S. N. Gonzalez-Diaz, S. Nakajima, T. Slavyanskaya, T. Zuberbier, W. Burks, Z. Awad El-Sayed   +51 more
core   +14 more sources

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Clinical Characteristics and Development of Complications Differ Between Adult-Onset and Child–Adolescent-Onset Type 1 Diabetes: A Report From a Tertiary Medical Center in Türkiye

Journal of Diabetes Research
Conclusion: Clinical presentation and prognosis differ in adult-onset and child–adolescent-onset T1DM. Low initial C-peptide may predict the development of microvascular and macrovascular complications.
Ramazan Çakmak, Özge Telci Çaklılı, Ayşe Merve Ok, Ümmü Mutlu, Göktuğ Sarıbeyliler, Vefa Seferova Nasifova, Ersel Bilgin, Aylin Çoşkun, Damla Yenersu Guzey, Utku Erdem Soyaltin, Servet Yüce, Hülya Hacışahinoğulları, Gülşah Yenidünya Yalın, Özlem Soyluk Selçukbiricik, Nurdan Gül, Ayşe Kubat Üzüm, Kubilay Karşıdağ, Nevin Dinççağ, Mehmet Temel Yılmaz, Ilhan Satman   +19 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Benefits of connecting rfid and lean principles in health care [PDF]

, 2005
The performance management process in health care is far behind compared to the manufacturing and service industries. Although nowadays the health care organizations are able to deal with a greater rank diseases, their cost, quality and delivery has ...
Aguado Correa, Francisco, Barcos, Lucía, Álvarez Gil, María Joséfa   +2 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

An Approach to the Stepwise Management of Severe Mitral Regurgitation with Optimal Cardiac Pacemaker Function

Indian Pacing and Electrophysiology Journal, 2014
Right ventricular apical pacing may cause or worsen mitral regurgitation (MR). Potential mechanisms for this adverse sequelae include intraventricular dyssynchrony, altered papillary muscle function, pacing-induced cardiomyopathy with left ventricular ...
Christopher V. DeSimone, MD, PhD, Vuyisile T. Nkomo, MD, MPH, Daniel C. DeSimone, MD, Lawrence R. Keenan, MD, Maurice Enriquez-Sarano, MD, Samuel J. Asirvatham, MD   +5 more
doaj   +1 more source

Decrease in late presentation for HIV care in Kinshasa, DRC, 2006–2020

AIDS Research and Therapy, 2021
Introduction Late presentation for HIV care is a well-described issue for the success of ART outcomes and the cause of higher morbidity, mortality and further transmission.
Nadine Mayasi Ngongo, Hippolyte Situakibanza Nani-Tuma, Marcel Mbula Mambimbi, Murielle Longokolo Mashi, Ben Bepouka Izizag, Faustin Kitetele Ndolumingu, Nathalie Maes, Michel Moutschen, Gilles Darcis   +8 more
doaj   +1 more source

Elderly Nutrition Problems. [PDF]

, 2014
In old age people suffer from internal organs diseases very often. More than 90% of the elderly have these diseases. As much as one third of all older people complain of cardiovascular, respiratory and digestive diseases, diseases of the ...
Кравченко, В. С.
core