Results 21 to 30 of about 168 (149)

Five Anastasiae and Two Febroniae: A Guided Tour in the Maze of Anastasia Legends. Part One. The Oriental Dossier [PDF]

open access: yes, 2021
The recent data related to the legend of St Anastasia in Byzantium require a fresh analysis of the mutually connected cults of Anastasia and Febronia in both the Christian East and West.
Basil Lourié
core   +2 more sources

Environmental Impacts of Planned Capitals and Lessons for Indonesia’s New Capital [PDF]

open access: yes, 2020
Indonesia’s new planned capital in East Kalimantan is being touted as a “smart, green, beautiful and sustainable city” but has stoked fears of massive environmental damage to the island of Borneo, one of the world’s most important biodiversity hotspots ...
Campos-Arceiz, Ahimsa   +3 more
core   +1 more source

PEMBERDAYAAN MASYARAKAT BERBASIS HUMAN CAPITAL DALAM MENGHADAPIANCAMAN NONMILITER DI KAWASAN WISATA PUNCAK KABUPATEN BOGOR [PDF]

open access: yes, 2021
Penelitian ini mengkaji tentang pemberdayaan masyarakat berbasis Human Capital di Kawasan wisata Puncak, Kabupaten Bogor sebagai salah satu destinasi wisata mancanegara khususnya dari Timur Tengah.
GREGORIUS HENU BASWORO, .
core  

Persistence of the past and the here-and-now of the Union Buildings [PDF]

open access: yes
In their presence and continued use as seat of government, the Union Buildings in Pretoria reveal the persistence of the past in a prime space of power and official commemoration in South Africa.
Mabin, Alan
core   +2 more sources

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego   +10 more
wiley   +1 more source

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich   +5 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Women Informal Business Tourists in Urban Southern Africa: Circuits, Drivers and Challenges [PDF]

open access: yes
Across sub-Saharan Africa, a substantial economy benefits from informal business tourism. In Southern Africa, the central element in informal business tourism is women's activities as informal cross-border shoppers and traders.
Rogerson, Christian M.   +1 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

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