Results 61 to 70 of about 2,274,127 (250)
TIPA. Travaux interdisciplinaires sur la parole et le langageSeveral research studies have indicated that the development of digital reading and writing competencies represents a major educational challenge, as it affects young generations’ social interactions, their agency, and their ability to build and access ...
Eleonora Acerra +2 more
doaj +1 more source
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
FEBS Letters, EarlyView.Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Ziemia niczyja. Zwroty badawcze w literaturoznawstwie i ich konsekwencje dla nauczania literatury
Postscriptum Polonistyczne, 2020 The author of the article poses a question concerning adequacy of research proposals inspired by the circle called ‘the ethic of reading’ and ‘theological return’.
Krystyna Koziołek
doaj
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Reading Circle List for 2014 [PDF]
, 2014 Reading Circle is a monthly event organised by the Faculty of Social Sciences. The objective is to inculcate the spirit of inquiry and intellectual discussion based on the readings of key texts in social sciences.
Sharifah S., Wan Ahmad
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Reading Circle List for 2012 [PDF]
, 2012 Reading Circle is a monthly event organised by the Faculty of Social Sciences. The objective is to inculcate the spirit of inquiry and intellectual discussion based on the readings of key texts in social sciences.
Sharifah S., Wan Ahmad
core
مجلة الآدابThe current study aims to explore the impact of using literature circles strategy on supporting EFL college students ‘reading comprehension skills and motivation towards reading.
Zainab Jawad
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source