Results 11 to 20 of about 1,826 (150)

甲状腺乳头状癌雌激素受体β表达及其 5′非翻译区甲基化 [PDF]

open access: yes, 2020
【目的】研究甲状腺乳头状癌(PTC)中雌激素受体β基因(ERβ)表达及 5′非翻译区甲基化状态,探讨ERβ在 PTC 中低表达的原因。【方法】应用 Western blot 和免疫组织化学染色法检测正常甲状腺细胞Nthy-ori3-1、PTC 细胞 BCPAP 以及正常甲状腺组织、甲状腺结节性增生组织和 PTC 组织ERβ蛋白表达;应用 qRT-PCR 检测各细胞和组织中 ERβ mRNA(0K-1)、ERβ mRNA(0N-1)和总 ERβ mRNA 表达水平;亚硫酸氢盐测序分析各细胞和组织中 ERβ
刘智敏, 苟茜, 许琳婉
core  

Using colorimetric in situ hybridisation method for FcaPV‐2 to estimate postsurgical prognosis in feline Bowenoid in situ carcinoma

open access: yesVeterinary Dermatology, Volume 36, Issue 1, Page 83-91, February 2025.
Background – Feline Bowenoid in situ carcinoma (BISC) is frequently associated with Felis catus papillomavirus‐2 (FcaPV‐2). Although surgical excision of BISC is expected to be curative, recurrent lesions are reported and it is not known whether it is a consequence of incomplete surgery or residual viral load.
Francesca Abramo   +7 more
wiley   +1 more source

Development and validation of the NCC‐BC‐A scale to assess patient‐reported outcomes for breast cancer patients in China

open access: yesCancer Innovation, Volume 3, Issue 6, December 2024.
This study developed a NCC‐BC‐A scale with relatively high validity and reliability for breast cancer (BC) patients. NCC‐BC‐A scale fully considered the characteristics of systemic treatment status for BC and the realistic situation in China, which may help clinicians to pay more attention to QOL of BC patients and to optimize management system for BC.
Fei Ma   +4 more
wiley   +1 more source

甲状腺乳头状癌颈侧区淋巴结转移危险因素分析 [PDF]

open access: yes, 2019
【目的】探究甲状腺乳头状癌(PTC)颈侧区淋巴结转移的临床特征。【方法】回顾性分析皖南医学院附属弋矶山医院2011年6月1日至2018年5月30日收治的PTC患者临床资料。【结果】本研究共纳入241例病例。术后常规病理证实颈侧区淋巴结转移率73.44%(177/241)。与颈侧区淋巴结无转移的PTC患者相比,伴颈侧区淋巴结转移的PTC患者年龄偏小,多为女性,癌肿直径较大,颈中央区淋巴结转移数目较多,超声及CT检查积分更高。而BMI指数、桥本氏甲状腺炎病史及甲亢病史对PTC颈侧区淋巴结转移率无显著性影响。【
方芳
core  

Clinicopathological features of patients with solid papillary carcinoma of the breast: An analysis of 144 cases [PDF]

open access: yes
Objective To investigate the clinicopathological features and prognosis of patients with solid papillary carcinoma (SPC) of the breast. Methods A retrospective analysis was performed for the clinical data of 144 patients with SPC of the breast who were ...
WANG Jingnan, LIU Yixuan, LI Xueqing, KONG Weimao, WANG Jigang
core   +1 more source

甲状腺微小乳头状癌中央区淋巴结转移相关因素分析

open access: yesZhongguo shiyan zhenduanxue, 2014
甲状腺微小乳头状癌(Papillary thyroid microcarcinoma,PTMC)是指肿瘤直径≤1.0厘米的甲状腺乳头状癌(Papillary thyroid carcinomaTMC),生存率高,预后好。十年生存率可达90%以上[1]。随着近年来诊断水平的提高,甲状腺微小乳头状癌在甲状腺乳头状癌中所占的比例明显增高[2]。国外报道[3,4],PTMC约占甲状腺癌的6%-63.7 ...
高虹, 孙丽丽, 佟凌霞
doaj  

Integrated diagnosis and treatment pathway for papillary thyroid carcinoma (initial diagnosis): expert consensus of Thyroid Center of the Third Affiliated Hospital of Sun Yat-sen University [PDF]

open access: yes
In recent years, the incidence of papillary thyroid carcinoma (PTC) in China has increased significantly. Thus, it is necessary to standardize the procedures of diagnosis, treatment and follow-up.
Thyroid Center of the Third Affiliated Hospital of Sun Yat-sen University
core   +1 more source

接合物蛋白检测在甲状腺乳头状微小癌中的临床诊断意义

open access: yesZhongguo shiyan zhenduanxue, 2014
目的探讨甲状腺乳头状微小癌中接合物蛋白(CRKL)的表达及其临床检测意义。方法收集2010-2013年我院收治的120名病人的甲状腺组织石蜡标本,其中30例为直径>1cm的甲状腺乳头状癌患者,30例为甲状腺乳头状微小癌患者,30例为结节性甲状腺肿患者,30例为未患甲状腺相关疾病的患者,采用免疫组化(SP)法检测标本中CRKL的表达情况。结果甲状腺乳头状微小癌组和甲状腺乳头状癌组组中CRKL的表达阳性率及平均吸光度(MOD)高于结节性甲状腺肿组和正常甲状腺组,差异均有统计学意义 ...
敖永琴
doaj  

PES1上调ERα/ERβ蛋白比率促进甲状腺乳头状癌细胞增殖和侵袭迁移 [PDF]

open access: yes, 2020
目的研究PES1通过上调ERα/ERβ蛋白比率促进甲状腺乳头状癌(PTC)细胞增殖和侵袭转移的分子机制。方法用免疫组化法检测PES1、ERα和ERβ在正常甲状腺组织以及PTC组织中的表达情况;用Western blot法分别检测正常甲状腺细胞株Nthy-ori3-1和PTC细胞株BCPAP和K1中PES1、ERα 和 ERβ的表达情况,以及PES1过表达、PES1下调时对Nthy-ori3-1细胞和BCPAP细胞中ERα、ERβ蛋白表达比率的影响;用MTT以及Transwell小室法检测PES1 ...
刘智敏, 程龙, 许琳婉, 邱伊波
core  

Preliminary application of improved 3D printed pathological section box to assisting stitching pathological images of bone tumor [PDF]

open access: yes, 2023
Objective·To explore the feasibility of applying improved pathological section boxes based on image post-processing and 3D printing technology to assisting artificial intelligence (AI) in stitching pathological images of bone tumors.Methods·Bone tumor ...
AI Songtao   +6 more
core   +1 more source

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