Results 11 to 20 of about 2,054 (150)
甲状腺乳头状癌雌激素受体β表达及其 5′非翻译区甲基化 [PDF]
【目的】研究甲状腺乳头状癌(PTC)中雌激素受体β基因(ERβ)表达及 5′非翻译区甲基化状态,探讨ERβ在 PTC 中低表达的原因。【方法】应用 Western blot 和免疫组织化学染色法检测正常甲状腺细胞Nthy-ori3-1、PTC 细胞 BCPAP 以及正常甲状腺组织、甲状腺结节性增生组织和 PTC 组织ERβ蛋白表达;应用 qRT-PCR 检测各细胞和组织中 ERβ mRNA(0K-1)、ERβ mRNA(0N-1)和总 ERβ mRNA 表达水平;亚硫酸氢盐测序分析各细胞和组织中 ERβ
刘智敏, 苟茜, 许琳婉
core
Background – Feline Bowenoid in situ carcinoma (BISC) is frequently associated with Felis catus papillomavirus‐2 (FcaPV‐2). Although surgical excision of BISC is expected to be curative, recurrent lesions are reported and it is not known whether it is a consequence of incomplete surgery or residual viral load.
Francesca Abramo +7 more
wiley +1 more source
This study developed a NCC‐BC‐A scale with relatively high validity and reliability for breast cancer (BC) patients. NCC‐BC‐A scale fully considered the characteristics of systemic treatment status for BC and the realistic situation in China, which may help clinicians to pay more attention to QOL of BC patients and to optimize management system for BC.
Fei Ma +4 more
wiley +1 more source
【目的】探究甲状腺乳头状癌(PTC)颈侧区淋巴结转移的临床特征。【方法】回顾性分析皖南医学院附属弋矶山医院2011年6月1日至2018年5月30日收治的PTC患者临床资料。【结果】本研究共纳入241例病例。术后常规病理证实颈侧区淋巴结转移率73.44%(177/241)。与颈侧区淋巴结无转移的PTC患者相比,伴颈侧区淋巴结转移的PTC患者年龄偏小,多为女性,癌肿直径较大,颈中央区淋巴结转移数目较多,超声及CT检查积分更高。而BMI指数、桥本氏甲状腺炎病史及甲亢病史对PTC颈侧区淋巴结转移率无显著性影响。【
方芳
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The diagnostic value of elastography and ultrasound contrast in papillary thyroid microcarcinoma [PDF]
目的 评估弹性成像与超声造影(CEUS)两种检查技术对鉴别诊断甲状腺微小乳头状癌(TMC)的价值。方法 对常规超声检测出且定性困难的73例80个甲状腺微小结节进行弹性成像及CEUS检查,所有结节均经手术病理证实。比较两种检查方法的准确性。结果 80个结节中CEUS诊断正确率为85.0%(68/80),其中6例TMC误诊为良性病变,6例良性结节误诊为TMC;弹性成像5分法诊断正确率为92.5%(74/80),其中3例TMC误诊为良性结节,3例良性结节误诊为TMC。性成像诊断甲状腺微小癌的敏感性94.0%,
An, Yuan +7 more
core +2 more sources
Clinicopathological features of patients with solid papillary carcinoma of the breast: An analysis of 144 cases [PDF]
Objective To investigate the clinicopathological features and prognosis of patients with solid papillary carcinoma (SPC) of the breast. Methods A retrospective analysis was performed for the clinical data of 144 patients with SPC of the breast who were ...
WANG Jingnan, LIU Yixuan, LI Xueqing, KONG Weimao, WANG Jigang
core +1 more source
甲状腺微小乳头状癌(Papillary thyroid microcarcinoma,PTMC)是指肿瘤直径≤1.0厘米的甲状腺乳头状癌(Papillary thyroid carcinomaTMC),生存率高,预后好。十年生存率可达90%以上[1]。随着近年来诊断水平的提高,甲状腺微小乳头状癌在甲状腺乳头状癌中所占的比例明显增高[2]。国外报道[3,4],PTMC约占甲状腺癌的6%-63.7 ...
高虹, 孙丽丽, 佟凌霞
doaj
目的在成纤维细胞3T3随机突变试验中证实中肿瘤易感基因TSG101是一个潜在的肿瘤抑制基因,探讨肿瘤易感基因TSG101在甲状腺乳状癌组织中的表达情况。方法采用免疫组织化学方法(SP法)检测40例甲状腺乳头状癌和相应癌旁正常甲状腺滤泡上皮中的TSG101的表达情况,采用Western blot方法检测TSG101在20例甲状腺乳头状癌和10例相应癌旁正常甲状腺滤泡上皮中的蛋白表达情况。结果TSG101在甲状腺乳头状癌中表达率为80%,TSG101在甲状腺乳头状癌中的表达明显高于相应癌旁正常甲状腺滤泡上皮,
陆平, 赵文杰, 张岩, 张彦慧
doaj
Integrated diagnosis and treatment pathway for papillary thyroid carcinoma (initial diagnosis): expert consensus of Thyroid Center of the Third Affiliated Hospital of Sun Yat-sen University [PDF]
In recent years, the incidence of papillary thyroid carcinoma (PTC) in China has increased significantly. Thus, it is necessary to standardize the procedures of diagnosis, treatment and follow-up.
Thyroid Center of the Third Affiliated Hospital of Sun Yat-sen University
core +1 more source
PES1上调ERα/ERβ蛋白比率促进甲状腺乳头状癌细胞增殖和侵袭迁移 [PDF]
目的研究PES1通过上调ERα/ERβ蛋白比率促进甲状腺乳头状癌(PTC)细胞增殖和侵袭转移的分子机制。方法用免疫组化法检测PES1、ERα和ERβ在正常甲状腺组织以及PTC组织中的表达情况;用Western blot法分别检测正常甲状腺细胞株Nthy-ori3-1和PTC细胞株BCPAP和K1中PES1、ERα 和 ERβ的表达情况,以及PES1过表达、PES1下调时对Nthy-ori3-1细胞和BCPAP细胞中ERα、ERβ蛋白表达比率的影响;用MTT以及Transwell小室法检测PES1 ...
刘智敏, 程龙, 许琳婉, 邱伊波
core

