Results 1 to 10 of about 1,368,425 (144)
Confidence in public institutions is critical in containing the COVID‐19 pandemic
Abstract This paper investigates the relative importance of confidence in public institutions to explain cross‐country differences in the severity of the coronavirus disease 2019 (COVID‐19) pandemic. We find that a 1 SD increase (e.g., the actual difference between the United States and Finland) in confidence is associated with 56.3% fewer predicted ...
Anna Adamecz, Ágnes Szabó‐Morvai
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Objective To investigate the effect of rubbing therapy with Chinese herbal medicine ointment on pain relief in patients with hyperplasia of mammary gland. Methods Totally 40 patients suffering from pain caused by mammary gland hyperplasia were randomly
LIU Kexin (刘可欣) +2 more
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Abstract Background The molecular phenotype of circulating tumor cells (CTCs) was associated with clinical outcome of patients with breast cancer. CTCs isolated from patients with metastatic breast cancer (MBC) display a unique microRNA (miRNA) expression profile.
Weige Tan +11 more
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Aspect Ratio‐Controlled Chiral Nanostructures for Dual‐Mode Breast Cancer Theranostics
ABSTRACT Chiral CdSe/CdS quantum dots (QDs) have emerged as promising platforms for precise cancer diagnosis and therapy due to their unique optical properties and biological interactions. In this study, we systematically investigated the role of aspect ratio (AR) modulation in ultrathin‐shelled chiral CdSe/CdS dot‐in‐rods (DRs) on their performance in
Linxuan Wu +9 more
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This study developed a NCC‐BC‐A scale with relatively high validity and reliability for breast cancer (BC) patients. NCC‐BC‐A scale fully considered the characteristics of systemic treatment status for BC and the realistic situation in China, which may help clinicians to pay more attention to QOL of BC patients and to optimize management system for BC.
Fei Ma +4 more
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BRCA2通过PI3K/AKT通路上调ATM抑制乳腺癌的增殖、迁移和侵袭
目的探讨BRCA2通过调控PI3K/AKT通路上调ATM的表达,影响乳腺癌细胞生长、迁移和侵袭。方法运用PCR技术扩增人乳腺BRCA2基因,将其克隆至真核表达载体pCDNA3.1-coGFP中,酶切和测序验证后转染至乳腺癌BT474细胞中。采用Western blot检测实验组和对照组细胞中BRCA2、ATM、Rad51、PALB2蛋白的表达,采用免疫组化分析人乳腺癌组织中BRCA2和ATM蛋白的表达,采用CCK8法和流式细胞仪分别测定各组细胞生长和凋亡变化 ...
梅楠 +5 more
doaj
目的探讨雌、孕激素受体在女性乳腺癌与各种增生性病变组织中的表达及临床意义。方法取2006年2月至2007年2月中日联谊医院乳腺甲状腺外科手术后经病理科诊断证实的病例,乳腺增生性疾病52例(40人),乳腺癌52例(49人)。其中普通型增生10例,轻度非典型增生12例,中度非典型增生9例,重度非典型增生21例,乳腺浸润性导管癌52例。用免疫组化SP法检测ER、PR的表达。结果在乳腺普通型增生、轻、中、重度非典型增生及乳腺浸润性导管癌组织中ER表达的阳性率分别为30.00%、41.67%、44.44%、61 ...
于宏, 续哲莉
doaj
目的建立类似男性乳腺增生模型,观察腺体变化,探讨乳腺增生发病机制。方法采用苯甲酸雌二醇诱导雄性大鼠发生乳腺增生,观察大鼠大体变化、乳腺组织结构、测定体内生殖激素水平。结果实验组动物血液中的雌二醇的浓度均高于对照组,腺体组织明显增生。结论本模型的建立,较好的体现了男性乳腺增生的临床特点,给后续的实验研究提供了实验基础。
王学魁, 张敏, 续哲莉
doaj
乳腺增生症是指乳腺上皮和纤维组织增生、乳腺组织导管和乳小叶在结构上的退行性病变及进行性结缔组织的生长,是临床上常见的一种乳腺疾病,其发病原因主要是由于内分泌激素失调及精神因素所引起,好发于青春期以后的任何年龄,但以中年妇女多见。乳腺增生症与乳腺癌的关系密切 ...
陈丽芹, 朱会玲, 方宏, 李素荣
doaj
乳腺增生(hyperplasia of breast)是指乳腺上皮和纤维组织增生,乳腺组织导管和乳小叶在结构上的退行性病变及进行性结缔组织的生长,其发病原因主要是由于内分泌激素失调[1]。作为女性最为常见的乳房疾病,应进行提前预防以降低损害后果。目前乳腺增生的发病原因及病理机制均未完全明晰,
苏富芳, 饶媛媛
doaj

