正常乳腺组织和浸润性乳腺癌组织中淋巴增强因子-1(LEF-1)转录因子的蛋白质表达水平的分析
目的通过实验对正常乳腺组织和浸润性乳腺癌组织中淋巴增强因子-1(LEF-1)转录因子的蛋白质表达水平进行分析,观察其差异。方法对从手术获得的新鲜乳腺组织做冰冻切片,经H&E染色分析鉴定出正常乳腺组织和乳腺浸润癌组织。用显微切割方法获取目标组织,再采用蛋白质免疫印迹法(Westen blot)检测正常乳腺组织和乳腺浸润癌组织中LEF-1转录因子的蛋白质表达差异。结果乳腺浸润癌组织中的LEF-1转录因子的蛋白质表达水平高于正常乳腺组织中的LEF-1转录因子的蛋白质表达水平。结论LEF ...
盖晋宏 +5 more
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从上世纪70年代以来,全球患有乳腺癌的患者越来越多,据统计,美国平均8名妇女中就有1名乳腺癌患者[1]。近年来,乳腺癌的发病率在我国也逐年攀升,我国登记的各类肿瘤发病率中,女性乳腺癌发病率位居恶性肿瘤第一位[2]。影像学检查能及早诊断乳腺癌,有利于控制病情发展,提高疗效,乳腺造影和弹性成像是常用的诊断方法[3]。1材料与方法1 ...
葛嘉 +7 more
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[Fertility management in breast cancer patients: current strategies and research advances]. [PDF]
Zhou J, Jin M, Huang H.
europepmc +1 more source
[Molecular mechanisms and clinical applications of anti-angiogenic therapy in precision treatment of breast cancer]. [PDF]
Wang H, Jiang Y.
europepmc +1 more source
[Erianin inhibits proliferation and migration of breast cancer cells <i>in vitro</i> by inhibiting Wnt/β-catenin signaling]. [PDF]
Fan D +5 more
europepmc +1 more source
[Construction of a ubiquitination-related gene prognostic model for breast cancer based on taxane treatment response]. [PDF]
Luo H +5 more
europepmc +1 more source
[Role and mechanisms of FoxO3a-related signaling pathways in breast cancer cell apoptosis]. [PDF]
Wang Z +5 more
europepmc +1 more source
[Image-guided application of plant pigment patch and laser microdot ablation for surface marking in radiotherapy for breast cancer: a randomized controlled trial]. [PDF]
Fang L +6 more
europepmc +1 more source
Roles of lncRNA in the diagnosis and prognosis of triple-negative breast cancer. [PDF]
Yang Q, Fu Y, Wang J, Yang H, Zhang X.
europepmc +1 more source
运用凝集素亲合组化对100例乳腺癌进行了定位研究,结果表明:蓖麻素(RCA)在8例乳腺导管内癌7例阳性,而在其它类型乳腺癌阳性率均低 ...
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