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Zhongshan Daxue xuebao. Yixue kexue ban, 1984 乳腺脂肪肉瘤罕见。国内11所医院于1973年之前收治的乳腺肿瘤的资料中,脂肪肉瘤仅仅1例,而这例至今未见有详细报告。我科曾收治1例,报告如下。临床资料患者女,23岁,因右乳腺肿块一年于1975年8月27日入院。入院前一年,患者无意中发现右乳腺肿块约指头大小,无不适感。10个月后,肿块逐渐增大如鸡蛋大小。入院前2月,肿块急剧增大,外院用青霉素、链霉素等抗炎治疗无效。
杨名添
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Review of the role of collagen in tumorigenesis and development [PDF]
, 2023 Collagen is one of the most abundant proteins in the body and is the main component of the extracellular matrix. Collagen regulates cellular behavior, and its dysregulation can cause a variety of diseases, including cancer.
TANG Lei, XU Yingchun, ZHANG Fengchun
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Advances in fundamental and translational breast cancer research in 2022 [PDF]
, 2023 According to the data released by the International Cancer Research Institute of the World Health Organization (WHO), breast cancer is the malignant tumor with the highest incidence rate in women, and seriously endangers women's health.Many impressive ...
WANG Ziyu, XIAO Yi, JIANG Yizhou, SHAO Zhimin
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智能科学与技术学报, 2023 乳腺肿瘤严重影响女性的身心健康。病理学图像分析是医生诊断乳腺肿瘤的一个重要方法，不同类型肿瘤细胞的结构具有高度的相关性，这使得常规方法的诊断不易进行。改进的EfficientNet被用来诊断乳腺肿瘤，其使网络模型能自动学习疾病的特征并提高乳腺肿瘤诊断的准确率。基于此，首先，采用卷积块注意力模型提取乳腺肿瘤病理图像的有效特征；其次，引入分组卷积和通道混洗操作来提高模型的特征表达能力；再次，利用Hard-Swish激活函数提升模型的收敛速度；最后 ...
方祯祺, 李雪, 莫红
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Compared the efficacy of mitoxantrone hydrochloride injection for tracing with radionuclide in sentinel lymph node biopsy of breast cancer [PDF]
, 2023 Background and purpose: Both domestic and foreign guidelines recommend the use of radionuclide as sentinel lymph node (SLN) biopsy (SLNB) tracer, however this technique has not been popularized in China for a variety of reasons.
YANG Benlong, JIAO Dechuang, CHEN Jiajian, WANG Chunjian, JIN Lidan, ZHAO Wenhe, GAO Xueqiang, WANG Haibo, LI Jun, ZHAO Haidong, WU Di, FAN Zhimin, WANG Shujun, LIU Zhenzhen, WANG Yongsheng, WU Jiong
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Progress of important clinical trials of breast cancer in China in 2022 [PDF]
, 2023 Breast cancer has become the most common type of cancer in the world, harming the majority of women's physical and mental health and challenging clinical prevention and treatment of tumors.
SHAO Zhibo, YANG Benlong, WU Jiong
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Standardization of multi disciplinary team treatment for breast cancer (2023 edition) [PDF]
, 2023 Breast cancer has become the most common malignant tumor in the world since 2020. With the diagnosis and therapeutic regimens improvement in breast cancer, survival rate of Chinese patients has been significantly enhanced in recent years.
Energizing Specialty Construction-Multidisciplinary Expert Committee for Creating Healthy China, The Society of Breast Cancer China Anti-Cancer Association
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The Oncologist, Volume 24, Issue 11, Page e1044-e1054, November 2019., 2019 Abstract Background The molecular phenotype of circulating tumor cells (CTCs) was associated with clinical outcome of patients with breast cancer. CTCs isolated from patients with metastatic breast cancer (MBC) display a unique microRNA (miRNA) expression profile.
Weige Tan +11 more
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Zhongguo shiyan zhenduanxue, 2021 乳腺化生性癌（MBC）于是一组具有明显异质性的罕见的乳腺侵袭性肿瘤,占所有乳腺恶性肿瘤的0.2%-1%[1]。乳腺梭形细胞化生癌（SPCC）是乳腺化生性癌的一种亚型,常发生在绝经后的妇女,平均发病年龄约在68岁。临床表现与浸润性导管癌相似,肿瘤平均直径约5.3cm（1.6cm-20cm）[2]。由于报道病例较少,病理组织学特征认识不足,极易误诊、漏诊。
杨大涛 +4 more
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OVOL2 antagonizes TGF-β signaling to regulate epithelial to mesenchymal transition during mammary tumor metastasis [PDF]
, 2016 关于TGF-β信号在诱导上皮-间质转化（EMT）过程中的作用的研究在多种肿瘤中已经取得了很大的进展，然而，在乳腺肿瘤转移的过程中，TGF-β信号对EMT的调控机制尚未完全探明。在本研究中，我们证明了OVOL2，一种锌指蛋白转录因子，能抑制小鼠肿瘤细胞、人乳腺肿瘤细胞中的TGF-β信号诱导的EMT。从Oncomine数据库中获得的数据表明，OVOL2的表达与乳腺癌的进展之间存在着很强的负相关关系。此外，我们的实验表明，OVOL2在多个水平上抑制TGF-β信号，包括抑制Smad4mRNA的表达 ...
吴容思
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