Results 21 to 30 of about 10,704 (119)

545例NIPT筛查高风险孕妇的产前诊断结果分析

Zhongguo shiyan zhenduanxue, 2021
目的探讨无创产前基因检测(NIPT)技术在产前诊断中的分析效能和临床应用价值。方法回顾性分析2013年9月至2018年12月于北京大学深圳医院就诊的545例NIPT筛查高风险并接受羊水穿刺孕妇(不包括双胎孕妇)的产前诊断结果。结果 545例NIPT高风险的孕妇中,21-三体165例、18-三体67例、13-三体41例、性染色体数目异常202例、常染色体数目异常49例、缺失或重复序列超过10Mb的结构异常病例21例,结合羊水细胞染色体核型分析发现21、18、13及性染色体NIPT假阳性率分别为11.5 ...
王贺, 肖晓素, 西仁娜依
doaj  

Aspirin delays preterm birth in pregnancies at high risk for preterm pre‐eclampsia: evidence from randomized clinical trial in Asia

Ultrasound in Obstetrics &Gynecology, Volume 66, Issue 1, Page 24-32, July 2025.
ABSTRACT Objectives To investigate the impact of aspirin administration on the incidence of preterm birth, according to the type of delivery and gestational age at preterm birth, and to examine the hypothesis that aspirin delays preterm delivery. Methods This was a secondary analysis of a multicenter stepped‐wedge cluster randomized trial of a first ...
H. H. Y. Leung, I. Papastefanou, Y. Chen, L. Nguyen‐Hoang, D.‐A. Nguyen, L. T. Dinh, R. K. Pooh, A. Shiozaki, M. Zheng, Y. Hu, Y. Wu, A. Kusuma, P. Yapan, A. Gosavi, A. Sekizawa, S. Luewan, T.‐Y. Chang, N. Chaiyasit, T. Nanthakomon, H. Liu, S. W. Shaw, W. C. Leung, A. S. Mohamad, A. Aguilar, S. L. Lau, N. M. W. Lee, J. Lin, D. S. Sahota, M. K. C. Chong, L. C. Poon   +29 more
wiley   +1 more source

三维超声在产前胎儿形态结构异常筛查中价值

Zhongguo shiyan zhenduanxue, 2011
本文对我院产前诊断80例形态结构异常患儿病例进行回顾性分析,探讨三维超声在产前诊断胎儿形态结构异常中的临床价值。1资料与方法1 ...
张歆, 薛玉, 尚梦园, 许建萍, 吕小利, 杜睿, 陈加俊   +6 more
doaj  

Detection of human cytomegalovirus cell‐free DNA in pregnant women with symptomatically infected fetuses: proof‐of‐concept study

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 470-477, April 2025.
ABSTRACT Objective To evaluate the presence and levels of cytomegalovirus (CMV) cell‐free DNA (cfDNA) fragments in women pregnant with a fetus with symptomatic congenital CMV (cCMV). Methods The study comprised nine women whose fetuses were diagnosed with cCMV between June 2019 and July 2024 at 20 + 4 to 34 + 1 weeks' gestation (n = 8) or neonatally (n 
B. H. W. Faas, T. Meuleman, G. Astuti, A. Reuss, K. Stol, E. A. Sistermans, J. Linthorst, E. van Leeuwen, J. Rahamat‐Langendoen, F. A. Wilmink   +9 more
wiley   +1 more source

中山医科大学附属第一医院产科优生优育研究动向

Zhongshan Daxue xuebao. Yixue kexue ban, 2000
作者综述我院产科近10 年来的研究动向, 包括:①产前诊断及宫内治疗方法, 实行羊膜腔穿刺和脐带穿刺对羊 水细胞及胎儿脐血进行分析, 以早期诊断及治疗一些先天性、遗传性和感染性疾病;②各种产前及产时监护手段的应用, 对了 解胎儿宫内发育, 早期发现胎儿宫内缺氧, 提高了对胎儿宫内情况诊断的准确性, 协助临床判断胎儿在宫内的安危, 为临床处 理提供一定的依据;③各种高危妊娠的监护和处理, 降低了围产期母婴的并发症和死亡率。
杨建波, 李大慈, 谢红宁, 朱　波, 游泽山, 孔秋英, 谭丽君, 周灿权, 李国梁   +8 more
doaj  

Prevention of hemoglobinopathies in Turkey

Thalassemia Reports, 2013
Hemoglobinopathies are the most common genetic disorders in Turkey. The incidence of beta thalassemia and sickle cell trait (HbAS) is 2.0% and 0.3% respectively. In addition to HbS, 51 abnormal hemoglobins and 42 different beta thalassemia mutations have
Mehmet Akif Çürük, Erdinç Yalın, Kıymet Aksoy   +2 more
doaj   +1 more source

N‐terminal pro B‐type natriuretic peptide as biomarker to predict pre‐eclampsia and maternal–fetal complications

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 447-455, April 2025.
ABSTRACT Objective A soluble fms‐like tyrosine kinase‐1 (sFlt‐1)‐to‐placental growth factor (PlGF) ratio cut‐off of 38 is currently considered optimal for ruling out pre‐eclampsia (PE); however, implementation of this ratio in clinical practice is limited.
M. N. Nan, C. Garrido‐Giménez, Á. Garcia‐Osuna, P. Garcia Manau, J. Ullmo, J. Mora, O. Sanchez‐Garcia, J. Platero, M. Cruz‐Lemini, E. Llurba, on behalf of the EuroPE working group, M. Vila‐Cortés, M. J. Pelegay, M. Ricart, B. Muñoz‐Abellana, X. Gabaldó Barrios   +15 more
wiley   +1 more source

Routine 36‐week scan: diagnosis and outcome of abnormal fetal presentation

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 2, Page 154-162, February 2025.
ABSTRACT Objectives First, to report the incidence of non‐cephalic presentation at a routine 36‐week ultrasound scan, the uptake and success of external cephalic version (ECV) and the incidence of spontaneous rotation from non‐cephalic to cephalic presentation.
M. Fitiri, D. Papavasileiou, V. Mesaric, A. Syngelaki, R. Akolekar, K. H. Nicolaides   +5 more
wiley   +1 more source

Primary prevention of hemoglobinopathies by prenatal diagnosis and selective pregnancy termination in a Muslim country: Oman

Thalassemia Reports, 2014
Hemoglobinopathies (HBP) are the most common genetic disorder in Oman and are in need of prevention programs due to the high incidence of β-thalassemia major and sickle cell disease. Prenatal diagnosis (PD) and selective pregnancy termination is shown to
Suha Mustafa Hassan, Egbert Bakker, Cornelis L. Harteveld, Piero C. Giordano   +3 more
doaj   +1 more source

Routine 36‐week scan: prediction of small‐for‐gestational‐age neonate

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 1, Page 20-29, January 2025.
ABSTRACT Objectives First, to compare the predictive performance of routine ultrasonographic estimated fetal weight (EFW) at 31 + 0 to 33 + 6 and 35 + 0 to 36 + 6 weeks' gestation for delivery of a small‐for‐gestational‐age (SGA) neonate. Second, to compare the predictive performance of EFW at 36 weeks' gestation for SGA vs fetal growth restriction ...
S. Adjahou, A. Syngelaki, M. Nanda, D. Papavasileiou, R. Akolekar, K. H. Nicolaides   +5 more
wiley   +1 more source