Results 11 to 20 of about 1,104 (121)

亲权鉴定中复杂案例的分析及对策 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2010
【目的】 探讨如何解决亲权鉴定中的复杂案例65377;【方法】 采用Identifiler + Sinofiler + Powerplex16系统对怀疑争议父母与亲生父母具有近亲关系的13户家庭(简称复杂家庭)成员进行检验并作统计学分析65377; 【结果】 13户复杂家庭中2户成员间的19个STR基因座(包括D8S117965380;D21S1165380;D7S82065380;CSFIPO65380;D3S135865380;TH0165380;D13S31765380;D16S53965380 ...
doaj   +2 more sources

非同位素标记pAW101探针作人流胚胎组织的亲权鉴定 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 1992
DNA限制性片段长度多态性(RFLPs)技术的经典方法是用酚抽提DNA,同位素标记探针。本文研究选用N_aCI盐析分离DNA的技术,结合地高辛配基标记pAW101探针方法,作了11例无争议的胚胎组织的亲权鉴定,同时测定4种同Ⅰ酶型,在不违反孟德尔遗规律的前提下,按Essen-Moller公式计算父权概率(均>99.73%),达到确定亲生关系的标准。本方法简单、易于掌握,结果稳定可靠,适宜于一般实验室开展工作。
doaj   +2 more sources

应用pAW101 DNA探针作人流胚胎组织的亲权鉴定 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 1992
用pAW1015kb的DNA片段为探针检测人流胚胎与其亲代的DNA限制性片段长度多态性(RFLPs)的遗传关系。同时测定他们的某些同工酶(葡萄糖磷酸变位酶、酯酶D、乙二醛酶Ⅰ)型。在不违反孟德尔遗传规律的前提下,按M(?)ller-Essen公式计算,其父权概率都已达到或超过可以确认亲生关系的标准。这一方法的建立,使过去棘手的早期妊娠的亲权鉴定之难题获得圆满解决。此外,本文还对这一方法的优越性进行了讨论。
doaj   +2 more sources

pAW101-EcoRⅠ限制性片段在广东人群中的分布及其在法医学上的应用

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 1992
用pAW1015kb的片段为探什,检测广东地区106例无血缘关系居民的EcoRI酶切限制性片段(RF)的分布情况。共发现长度各异的65条RF,每人只具有其中的1~2条。统计学分析证明,这些RF的分布符合哈一温氏平衡。无血缘关系的两个个体间具有完全相同的RF图谱的机会为0.00048(相当于l/2080)。家系调查结果表明,这些RF符合孟德尔遗传规律。本文是应用作者推导出来的计算RF大小的数学模式。此法在作亲权鉴定时,父权排除率可达0.914,相当于目前国内所用的血型测定法(包括HLA-A,-B抗原测定 ...
doaj   +1 more source

异父双生子亲权鉴定2例 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 1994
妇女在同一排卵周期,与不同男子发生性关系。会造成异父双生子的情况。本文报道2例异父双生子亲权鉴定情况,分别以Rh、Hp、HLA-A、HLA-B和HLA-A、HLA-B作为排除系统。
doaj   +2 more sources

Research Progresses of Tri-Allelic Patterns in Autosomal STR in Forensic DNA Analysis [PDF]

open access: yes, 2023
Tri-allelic pattern in autosomal STR is a common abnormal typing phenomenon in forensic DNA analysis, which brings difficulties and uncertainties to the evaluation of the evidence weight in actual cases. This paper reviews the types, formation mechanism,
Xiao-yan MA, Hong-yu SUN, Qing LI
core   +1 more source

General Formulas for Calculating Commonly Used Kinship Index [PDF]

open access: yes, 2023
Objective To derive general formulas for calculating commonly used kinship index (KI). Methods By introducing the Kronecker symbol, the formulas used to calculate the same KI under different genotype combinations were summarized into a unified expression.
Chao XIAO, Dai-xin HUANG
core   +1 more source

鲑鳟通用型低通量单核苷酸多态性芯片的开发 [PDF]

open access: yes, 2018
为开发常见鲑鳟养殖物种通用的遗传分析工具,本研究利用Affymetrix虹鳟(Oncorhynchus mykiss) 57K高通量单核苷酸多态性(Single nucleotide polymorphism,SNP)芯片,对国内代表性鲑鳟养殖群体开展了分型检测,包括山女鳟(Oncorhynchus masou masou)、银鲑(Oncorhynchus kisutch)、美洲红点鲑(Salvelinus fontinalis)、白斑红点鲑(Salvelinus leucomaenis) 4个物种 ...
张瀚元   +7 more
core   +1 more source

Polymorphisms of 19 Autosomal STR Loci in Sichuan Han Population and Their Forensic Application [PDF]

open access: yes, 2020
Objective To investigate the allele distribution, population genetics parameters and genetic analysis of neighboring populations of 19 autosomal STR loci in Sichuan Han population, and to evaluate their forensic application value. Methods The Goldeneye??
HUANG Yun, WANG Yu-zhuo, SONG Feng
core   +1 more source

Calculation of the Paternity Index for the Alleged Father Related to the Child’s Mother [PDF]

open access: yes, 2023
Objective To derive the paternity index (PI) calculation formula of the alleged father (AF) when the AF is a relative (parent/child, siblings, grandparent/grandchild, uncle/nephew, first cousins) of the child’s biological mother.
Yu-ting WANG, Qiang ZHU, Yu-han HU, Yi-fan WEI, Ting-yun HOU, Ji ZHANG
core   +1 more source

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