Results 51 to 60 of about 19,597 (184)
Boron Difluoride Chelated Aminoanthraquinone Photosensitizer for Type I Photodynamic Therapy
ABSTRACT Type I photosensitizers capable of generating cytotoxic reactive oxygen species (ROS), with reduced oxygen dependence under photoirradiation, are regarded as a promising phototherapeutic approach for hypoxic solid tumors. Herein, based on the electron donor of 9‐phenyl‐carbazole (Cz) and the electron acceptor of anthraquinone (AQ ...
Tian Zhang +8 more
wiley +1 more source
【目的】探讨前瞻性心电门控螺旋扫描联合低管电压、低对比剂注射速度及剂量技术在全主动脉及冠状动脉一 站式CT成像中的应用。【方法】收集心率≤ 75 次/min且心律齐的临床可疑主动脉病变或主动脉术后复查CT的患者60例, 将其随机分为两组,每组各30例。两组均采用320排CT前瞻性心电门控螺旋模式扫描,除实验组(G1)采用管电压80 kV、 对比剂注射速率3 m/s及对比剂容量0.65 mL/kg扫描方案,常规组(G2)组采用管电压120 kV、对比剂注射速率4 m/s及对比 剂容量1.2 mL ...
朱洪章 +5 more
doaj
Review of sea anemones compound and bioactivity [PDF]
海葵(sea anemone)又名海菊花,多指腔肠动物门(Coelenterata)珊瑚虫纲(Anthozoa)海葵目(actiniaria)动物。海葵一般分为爱氏海葵科、链索海葵科、细指海葵科、投海葵科、固边海葵科和绿海葵科等6科37种[1]。海葵体型大多呈圆筒状,触手以辐射对称状在口周围形成数轮,广泛分布在热带和温热带海域,主要固着在海中岩石上或泥沙中 ...
史文军, 吴建平, 张朝晖, 秦松
core
Recent Progress in the Development of Metal‐Based Radiosensitizations for Cancer Therapy: A Review
ABSTRACT Radiotherapy (RT) remains an indispensable means in cancer treatment; however, its therapeutic efficacy is often limited by tumor radioresistance and side effect of damage to healthy tissue. The advances in nanotechnology have propelled metal radiosensitizers to forefront of precision medicine.
Xiao‐Xia Wu +12 more
wiley +1 more source
目的探讨氧化乐果对大鼠骨骼肌组织氧化损伤的影响。方法将40只雄性Wistar大鼠随机分为4组,正常对照组,低剂量组,中剂量组和高剂量组,每组10只。低剂量组,中剂量组和高剂量组每天分别给予1/20、1/10、1/5LD50的氧化乐果,采用灌胃的途径给药,连续给药8周,检测大鼠血糖水平,骨骼肌组织中丙二醛(Malondialde-hyde,MDA)含量、超氧化物歧化酶(Superoxide dismutase,SOD)、过氧化氢酶(Catalase,CAT)和谷胱甘肽过氧化物酶(Glutathione ...
时佳宏 +6 more
doaj
The toxicity of Rapamycin derivatives—Everolimus, Deforolimus, Zotarolimus on islet [PDF]
目的:免疫抑制剂的开发与运用一直推动着器官移植领域的发展。自21世纪初,Edmonto方案被提出以后,胰岛移植领域发生的了质的飞跃,尤其是雷帕霉素与他克莫司的开发与利用,使得该方案得到广泛的认可与临床运用。然而随着研究的不断深入,研究者们发现免疫抑制剂在延长移植物存活时间的同时,也给胰岛本身带来了严重的毒性作用,包括抑制胰岛细胞增殖,促进胰岛细胞凋亡,抑制胰岛细胞分泌胰岛素等。应用免疫抑制剂产生的这些不良反应在抗器官移植排斥反应时发生。它们作为抗肿瘤药物应用于临床时也会诱发高血糖的现象。所以 ...
张娟
core
ABSTRACT Lithium‐sulfur batteries (LSBs) face sluggish sulfur reduction reaction kinetics and severe polysulfide shuttling issues, which significantly limit their performance. In this work, a multifunctional separator with a 3D porous framework featuring confined pore structures and selective adsorption capability is constructed to address these ...
Mengchen Zhang +12 more
wiley +1 more source
Background: Gabapentin reportedly decreases central sensitisation, a disorder associated with chronic pruritus in humans, although this is not well documented in cats. Its combined use with the standard antipruritic therapy for feline atopic skin syndrome (FASS) is not yet described.
Jeanne Morency +10 more
wiley +1 more source
Research of prevention and treatment of herb components HJJB compound on non-alcoholic steatohepatitisin rats induced by high-fat diet [PDF]
目的:探讨中药组分HJJB方(红景天苷、姜黄素、绞股蓝总苷、白术多糖)对高脂饮食诱导的大鼠非酒精性脂肪性肝炎的防治作用。方法:采用高脂饮食14周; 诱导大鼠非酒精性脂肪性肝炎模型。在造模第9周起,随机分为模型组,HJJB方高、低剂量组,罗格列酮组,灌胃给药6周。观察肝组织病理变化(HE染色); ,肝组织甘油三酯(TG)、游离脂肪酸(FFA)含量的变化,血清谷丙转氨酶(ALT)、谷草转氨酶(AST)、谷氨酰转肽酶(GGT)活性及TG、总胆; 固醇(TC)含量的变化。结果 ...
周飞 +5 more
core
ABSTRACT Objective To evaluate the impact of low‐dose aspirin (LDA) on placental size and uterine artery pulsatility index (UtA‐PI) by analyzing longitudinal changes between the first and second trimesters in pregnancies at high risk for early‐onset pre‐eclampsia (PE).
C. Trilla +7 more
wiley +1 more source

