Results 111 to 120 of about 28,669 (212)
Unravelling psychosis: Psychosocial epidemiology, mechanism and meaning. [PDF]
, 2015 This paper reviews a revolution in our understanding of psychosis over the last 20 years. To a major extent, this has resulted from a process of cross-fertilization between psychosocial epidemiology and cognitive behavior therapy for psychosis (CBT-p ...
Bebbington, PE
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Conservation Biology, EarlyView.Abstract Despite the crucial role of human impacts on biodiversity loss, many assessments of this loss focus on single metrics, such as species richness, and overlook the multidimensional effects of human activities. Because of its importance to ecosystem functioning, we investigated the functional diversity of medium‐ and large‐sized mammal ...
Xueyou Li +8 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2015 目的研究临床分离的铜绿假单胞菌(PA)对常见假丝酵母菌(包括白色假丝酵母菌、热带假丝酵母菌、光滑假丝酵母菌、近平滑假丝酵母菌、克柔假丝酵母菌和葡萄牙假丝酵母菌等)的抑制作用。方法通过革兰染色、菌落形态、氧化酶试验及上机鉴定收集临床上120株PA;通过纸片法检测PA对常见假丝酵母菌的抑制作用,根据对假丝酵母菌有无抑制作用将PA分为抑制性PA和非抑制性PA;利用十二烷基硫酸钠‐聚丙烯酰胺凝胶法(SDS‐PAGE)对两组PA进行分泌蛋白电泳,观察电泳条带的差异 ...
孙安民, 王伟
doaj
Study on transcription factors c-Jun and STAT from Litopenaeus vannamei during WSSV infection [PDF]
, 2016 凡纳滨对虾(Litopenaeusvannamei)是我国对虾养殖业的主要品种。然而，病害问题一直困扰着该产业的健康发展。其中白斑综合症病毒(whitespotsyndromevirus，WSSV)是对虾的主要病原体，给对虾产业造成了巨大的经济损失。截止目前，对WSSV还缺乏有效的治疗方法。因此，研究宿主病毒相互作用机制，对寻找阻断病毒感染的靶点具有重要意义。 c-Jun是JNK信号通路下游主要底物分子，参与调控了许多基因的转录。本实验室先前研究表明，凡纳滨对虾JNK被WSSV利用 ...
姚德福
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Conservation Biology, EarlyView.Abstract The design of experiments to investigate the combined effects of multiple stressors requires exposing target organisms to multiple combinations of stressor doses. Concurrent manipulation of stressors is often infeasible with wildlife, but long‐lasting health effects allow individual health to be used as an integrator of prior stressor exposure.
Enrico Pirotta +24 more
wiley +1 more source
Gaoya dianqi, 2017 高压开关电动操动机构的电气制动技术虽然是一项重要的应用技术,但是未得到足够的重视。因此,文中系统阐述了电气制动技术的工作原理及其技术特点,总结了工程应用中出现的常见问题与排查方法,利用Lab VIEW软件对样机的制动参数进行了测试。经分析得出:采用能耗制动,将电动机变为他励发电机,产生的制动能量使电动机构在0.3 s以内完成停车。根据电机回路电源类别选择不同的制动方式:永磁直流电动机为直流电源时,采用单电阻制动方式;串励电动机为单相交流电源,采用双电阻制动方式。在相同的制动回路中 ...
陈旭 +6 more
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Real Estate Taxes and Urban Sprawl [PDF]
, 2016 随着经济的迅速增长，我国城镇化建设的步伐也在快速地推进，取得了举世瞩目的成就，但也出现了大量城市占地面积增长过快的现象，进而引发了一系列经济社会问题。如何合理控制城市规模，促进城市土地资源高效利用，值得当下我们深度关注和思考。而房地产税具有促进土地集约利用并抑制城市过度扩张的功能，但其在我国仍没有得到应有的重视。本文以此为研究导向，对房地产税和城市扩张之间的关系进行深入详实地探讨，希望能对房地产税的理论分析和政策实践提供支撑和参考。 本文首先梳理了房地产税和城市扩张的相关文献 ...
贾雁岭
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Learning Styles, Engagement and Anxiety in AI‐Mediated Writing: A Multimodal Feedback Study
International Journal of Applied Linguistics, EarlyView.ABSTRACT Artificial intelligence (AI) tools now permeate English academic writing. However, evidence on how feedback modalities align with student differences and with psychological mechanisms remains limited. Prior work often reduced learning styles to simple matches with delivery modes and treated learning engagement and writing anxiety as peripheral.
Yi Ren +3 more
wiley +1 more source
蛋白酶体抑制剂MG132 通过FOXO3a/Puma 通路对急性T 淋 巴细胞白血病细胞增殖凋亡的影响
Zhongshan Daxue xuebao. Yixue kexue ban, 2017 ：【目的】研究蛋白酶体抑制剂MG132对急性T淋巴细胞白血病（T-ALL）细胞株的作用及其机制。【方法】将不 同浓度的MG132作用于T-ALL 细胞株CCRF-CEM，MTS 技术检测细胞增殖、流式细胞技术检测细胞凋亡。用qRT-PCR、 Western blotting分别从RNA及蛋白水平检测FOXO3a及其下游Puma的表达。利用慢病毒干扰技术构建FOXO3a-shRNA稳 定细胞株，再次验证MG132对其作用。【结果】MG132对CCRF-CEM细胞起抑制增殖、促进凋亡作用 ...
张祖涵 +5 more
doaj
Association between polycystic ovary syndrome and environmental endocrine disruptors: the pathogenetic mechanisms involved [PDF]
, 2016 摘要 多囊卵巢综合征(Polycysticovarysyndrome，PCOS)是一种在育龄妇女中常见的内分泌紊乱疾病，其常见特征为稀发排卵或少排卵、高雄激素血症、卵巢多囊化。PCOS的发病机制尚不明确，而许多研究表明环境因素是导致PCOS发病的重要因素。 本实验收集育龄妇女流行病学资料，并利用气象色谱-质谱联用检测了84名PCOS患者及94名对照组血清中多种环境中内分泌干扰物(endocrinedisruptingchemicals，EDCs)的含量。结合流行病调查资料和相关激素代谢物质水平 ...
郭致准
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