Results 81 to 90 of about 31,475 (181)

Study on the effects of down-regulating Annexin A3 expression on biological behaviors of lung adenocarcinoma and its molecular mechanism [PDF]

open access: yes, 2015
肺癌是我国第一大癌症,其发病率和死亡率均居恶性肿瘤之首,严重危害人类健康。肺癌按组织学类型可分为鳞癌、腺癌、小细胞癌和大细胞癌。近年来,肺腺癌(lungadenocarcinoma,AdC)的发病率呈逐步上升趋势,且患者死亡率高、预后极差。癌细胞易转移是肺腺癌患者预后差的主要原因,因此,探寻肺腺癌转移的分子机制及其新的治疗靶标,对于提高肺腺癌患者预后意义重大。我们前期研究中,采用定量蛋白质组学技术鉴定出AnnexinA3(Anxa3)为一个新的肺腺癌转移相关分子 ...
刘青青
core  

Internal physiological drivers of leaf development in trees: Understanding the relationship between non‐structural carbohydrates and leaf phenology

open access: yesFunctional Ecology, Volume 40, Issue 5, Page 1151-1164, May 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Plant phenology is crucial for understanding plant growth and climate feedback. It affects canopy structure, surface albedo, and carbon and water fluxes. While the influence of environmental factors on phenology is well‐documented, the role of plant intrinsic factors ...
Yunpeng Luo   +8 more
wiley   +1 more source

基于双信号检测及跟踪的真空断路器永磁机构控制方法研究

open access: yesGaoya dianqi, 2013
为了提高真空断路器永磁机构同步操作能力,有效抑制电力系统暂态过程。在断路器操作过程中,对多传感器输出信号进行检测,并采用双闭环PID控制方法对永磁机构进行控制,实现对目标参考触头行程、激磁线圈电流曲线的跟踪。以12 kV真空断路器单稳态永磁机构为控制对象,研制了以数字信号处理器(DSP)为核心的操作控制系统。结果表明控制系统采用上述控制方法,能够有效控制永磁机构触头行程与线圈电流,使触头运动特性处于受控状态,提高了控制系统的鲁棒性及控制精度,实现断路器关合时间误差在±0.3 ms以内 ...
汤庚, 徐建源, 林莘, 史可鉴
doaj  

Unravelling psychosis: Psychosocial epidemiology, mechanism and meaning. [PDF]

open access: yes, 2015
This paper reviews a revolution in our understanding of psychosis over the last 20 years. To a major extent, this has resulted from a process of cross-fertilization between psychosocial epidemiology and cognitive behavior therapy for psychosis (CBT-p ...
Bebbington, PE
core   +1 more source

Jellyfish blooms restructure plankton dynamics and trophic linkages in coastal waters

open access: yesFunctional Ecology, Volume 40, Issue 5, Page 1443-1460, May 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Jellyfish blooms are increasing globally in frequency and intensity, introducing complex ecological interactions, yet the mechanisms by which they alter ecosystem structure remain poorly characterized due to a lack of sustained field observations.
Pengpeng Wang   +4 more
wiley   +1 more source

沈阳高压开关厂新产品——35仟伏2000安GWD—35 2000型隔离开关

open access: yesGaoya dianqi, 1958
随着发电机容量的增大,我厂目前生产的仿苏(3)型隔离开关已不能滿足需要了。因此,我厂設計試制成功了一种35仟伏2000安GWD—35/2000型隔离开关。 一、概述 GWD—35/2000型隔离开关是由三个完整独立的单相組成,用瓦斯管連接。GWD—35/2000用型蝸輪操作机构来操作,GWD—35D/2000用型蝸輪操作机构来控制。仅能水平安装。
黄确亮
doaj  

A Study of Spatial-Temporal Difference and Spatial Effect of Pan-Yangtze River Delta’s Tourism Economy——A Spatial Econometrics Perspective [PDF]

open access: yes, 2016
由于我国区域间社会经济发展水平、基础设施条件、旅游资源禀赋、旅游服务水平等方面的差异,不同地区间旅游经济的发展会呈现不同的时空特征。同时在经济活动外部性的作用下,区域旅游经济发展也存在着某种程度的溢出效应。国内学者在对我国区域旅游经济发展差异的研究中,研究尺度多集中在省域范围,对旅游经济发展空间效应的研究还有待丰富。本文拟探究区域旅游经济发展时空差异特征及其空间效应,并根据实证结果提出对策建议,促进地区间旅游经济协调发展,形成相互联动、互利共赢的区域旅游发展格局 ...
冷翔
core  

Beyond Political Control and Bureaucratic Protection: Public Appointments for the Formation of Programmatic Groups and Representative Bureaucracy

open access: yesReview of Policy Research, Volume 43, Issue 3, May 2026.
ABSTRACT Public appointments shape the top‐level bureaucracy by serving as a gateway for professionals with different profiles, chosen based on different criteria. In general, the literature has been more interested in analyzing appointments based on merit or sponsorship, based on verification of loyalty to the government or technical competence ...
André Vaz Lopes   +1 more
wiley   +1 more source

TJ12/70B型双动力轮式通井机的研制与应用

open access: yesShiyou jixie, 2014
鉴于传统修井设备存在环境污染大,功率利用率低,维护和保养费用高等诸多问题,研制了TJ12/70B型双动力轮式通井机。该轮式通井机采用双动力技术,利用油田电网驱动高压调速电动机驱动绞车实现通井机修井作业,当电网断电或高压电机发生故障及特大载荷时,可以安全切换到柴油机驱动绞车进行修井作业,实现了高压调速电动机和柴油发动机双驱动的型式。开关磁阻电控系统与主机一体化安装,有利于控制作业成本、降低噪声及提高作业的可靠性。试验及现场应用结果表明,该轮式通井机电网驱动作业工况比柴油机驱动工况年碳排放减少984.68 ...
朱文琪   +4 more
doaj  

Role of RNA helicase DHX32 in the metastasis of hepatocellular carcinoma [PDF]

open access: yes, 2016
肝细胞癌是全球性的高致死率肿瘤之一,血管侵犯和转移是肝细胞癌患者术后易复发及5年生存率较低的重要原因,有效的抗转移策略无疑能给患者带来福音。因此,越来越多的研究致力于探讨肝细胞癌发生侵袭转移的分子机制,并希望通过找到某些关键分子来干预肿瘤的转移。 DHX32是人类RNA螺旋酶的家族成员之一,最早被发现是在急性淋巴细胞白血病中低表达并参与淋巴细胞的分化,但是它的生物学功能尚未明确。我们课题组前期通过差异基因显示技术发现DHX32在结直肠癌中表达上调,功能研究结果显示DHX32与结直肠癌细胞的增殖 ...
胡情
core  

Home - About - Disclaimer - Privacy