Results 31 to 40 of about 9,704 (160)
A dry eye model of C57BL/6 mouse induced by the topical application of benzalkonium chloride [PDF]
, 2016 目的：探究苯扎氯铵诱导C57BL/6小鼠干眼模型的最佳浓度，与局部应用苯扎氯铵对结膜及颈部淋巴结中炎症因子表达水平的影响。 方法：将60只小鼠分为6组，每组10只小鼠，在小鼠双眼结膜囊内滴入5μl不同浓度的苯扎氯铵（Benzalkoniumchloride，BAC）溶液（浓度分别为0.05%、0.075%、0.10%、0.15%、0.20%、0.25%），每天2次(9am，9pm)，持续7天，诱导小鼠干眼模型，另10只小鼠作为正常对照组，实验过程中，所有小鼠均置于正常环境条件下（即温度23±1 ...
彭高
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Veterinary Dermatology, Volume 35, Issue 6, Page 652-661, December 2024.Background – Mycophenolate is an immunomodulating agent successfully used for the treatment of moderate‐to‐severe atopic dermatitis (AD) in people. Mycophenolate is an effective steroid‐sparing treatment option for use in dogs with inflammatory skin diseases.
Michael Klotsman +5 more
wiley +1 more source
Veterinary Dermatology, Volume 35, Issue 5, Page 500-507, October 2024.Abstract Background Canine atopic dermatitis (cAD) is a hereditary, generally pruritic and predominantly T‐cell‐driven inflammatory skin disease, involving an interplay between skin barrier abnormalities, allergen sensitisation and microbial dysbiosis.
L. Widorn +2 more
wiley +1 more source
Veterinary Dermatology, Volume 35, Issue 1, Page 5-14, February 2024.Background – Canine atopic dermatitis (AD) is a complex inflammatory skin disease associated with cutaneous microbiome, immunological and skin barrier alterations. This review summarises the current evidence on skin barrier defects and on cutaneous microbiome dysfunction in canine AD.
Domenico Santoro +13 more
wiley +1 more source
Association of ambient air pollutants with blood physiological and biochemical indicators and systemic immune inflammation index in people living around Beijing: an analysis of air pollution and population health data [PDF]
ObjectiveTo investigate the association of ambient air pollutants with blood physiological and biochemical indicators and systemic immune inflammation index in people living around the Beijing metropolitan area and to provide a basis for formulating ...
Bingqian DU +3 more
core +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2006 【目的】探讨变应性鼻炎患者特异性免疫治疗(SIT)效果及其在防治支气管哮喘中的意义。【方法】对167 例螨过敏的持续性变应性鼻炎患者, 进行免疫治疗, 检测各治疗时期患者血清总免疫球蛋白 E (TIgE)、特异性免疫球蛋白 E (SIgE)和嗜酸性粒细胞阳离子蛋白(ECP)浓度, 并评估其过敏症状的变化。【结果】变应性鼻炎特异性免疫治疗后症状改善( P< 0.01) ; 儿童变应性鼻炎 SIT 效果较成人好( P< 0.01) 。此外, 观察期满 3 年的 49 例接受系统免疫治疗的患者与未系统治疗患者
瞿申红 +5 more
doaj
Predictive value of systemic immune inflammation index and somatic symptom scale-China in the occurrence of in-hospital major adverse cardiovascular events after first-episode of acute myocardial infarction undergoing PCI [PDF]
Objective·To investigate the predictive value of systemic inflammatory index (SII) and somatization symptom score-China (SSS-CN) for major adverse cardiovascular events (MACEs) in patients with first-episode acute myocardial infarction (AMI) undergoing ...
LI Shiguang +5 more
core +1 more source
免疫增强型肠内营养对胃癌根治病人术后免疫功能和炎症反应的影响
Zhongguo shiyan zhenduanxue, 2011 目的观察术后免疫增强型肠内营养对胃癌根治病人术后免疫功能及炎症反应的影响。方法胃癌根治病人42例,随机分为研究组、对照组,各21例。于术后1-8d,研究组使用含谷氨酰胺、精氨酸、ω-3多不饱和脂肪酸的免疫增强型肠内营养制剂,对照组使用常规的制剂能全力。观察术前1d、术后1d和术后9d;①T淋巴细胞亚群（CD4、CD8、CD4/CD8）、免疫球蛋白（IgG、IgM、IgA）;②肿瘤坏死因子（TNF-α）、血清中细胞因子白介素（IL-6）。结果研究组IgA、CD4水平及CD4/CD8显著高于对照组 ...
赵得新, 朱甲明, 陈云波
doaj
Role of E3 ubiquitin ligase Smurf1 in regulating NF-κB Signaling [PDF]
, 2016 核因子NF-kappaB是一种在哺乳动物体内广泛表达并且种属间高度保守的转录因子，它在免疫及炎症反应、生长发育、肿瘤形成等多个生理及病理学过程中发挥关键的调控作用。静息状况下，NF-kappaB与NF-kappaB抑制因子IkappaBalpha(InhibitorofNF-kappaB，IkappaBalpha)在胞质中形成复合物，其功能活性被抑制。但当细胞受到上游配体(例如肿瘤坏死因子alpha(tumornecrosisfactoralpha，TNFalpha)的刺激之后 ...
王群
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