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肺炎链球菌表面粘附素Ａ蛋白抗原表位的预测筛选及确定

Zhongshan Daxue xuebao. Yixue kexue ban, 2015
【目的】 确定肺炎链球菌表面粘附素Ａ（ＰｓａＡ）蛋白抗原的Ｂ细胞、ＣＤ４ Ｔ细胞和ＣＤ８ Ｔ细胞表位。【方法】 通过生物信息学方法预测肺炎链球菌ＰｓａＡ蛋白分子小鼠Ｂ细胞线性表位、ＭＨＣ－Ⅰ结合肽（ＣＤ８ Ｔ细胞表位）及ＭＨＣ－Ⅱ结合肽（ＣＤ４ Ｔ细胞表位）并人工合成相应肽段；克隆重组质粒ＢＬ２１／ｐＥＴ／ＰｓａＡ并得到纯化的ｒＰｓａＡ蛋白用以免疫小鼠；分离每只免疫组和对照组小鼠的血清分别与人工合成的候选Ｂ细胞表位肽段进行间接ＥＬＩＳＡ检测，筛选Ｂ细胞表位 ...
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[Refractory systemic lupus erythematosus-associated thrombocytopenia treated with avatrombopag: A case report]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Tang X, Ding Q, Zhang Y, Wang Y, Tian M, Sun Z, Wang R, Chen Y, Liu J.   +8 more
europepmc   +1 more source

[Retrospect and Prospect of Immune Caries Prevention Research in China]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Xu Q, Fan M.
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[Research progress on toxic shock syndrome due to group A <i>Streptococcus</i> infection in children]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Wang HY, Zhou W, Huang LS.
europepmc   +1 more source

[Rapid response to linperlisib in relapsed/refractory autoimmune hemolytic anemia: a case report]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Liu ZW, Chen M.
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[Multiple myeloma with massive proliferation of signet ring cell like plasma cells: a case report]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Bai ZY, Jin YL, Wu X, Zhang F, Liu HQ, Yang MR, Ji P.   +6 more
europepmc   +1 more source

[Exploring the research on the molecular mechanisms of autoimmune liver diseases]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Liu YQ, Jiang XW, Li Y, Liu XL.
europepmc   +1 more source

复发性口疮患者血清免疫球蛋白及抗核抗体 [PDF]

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core  

[Positive antinuclear antibodies suggest a high inflammatory burden phenotype: a multicenter retrospective analysis of patients with primary biliary cholangitis]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Li SS, Li RJ, Zhang Y, Ji WJ, Bao YJ, Liu HL, Gong YX, Wang YT, Tao YL, Wu ZX, Zhang Y, Zhang WH, Li W, Ye F, Yan XH, Mao TH, Liu X, Zhang K, Yang YF.   +18 more
europepmc   +1 more source

[Gut-vascular axis in Kawasaki disease: short-chain fatty acid-mediated immune regulation and therapeutic targets]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Wang SD, Liu F.
europepmc   +1 more source