Results 11 to 20 of about 6,226 (160)

Fatty acid β‐oxidation and mitochondrial fusion are involved in cardiac microvascular endothelial cell protection induced by glucagon receptor antagonism in diabetic mice 脂肪酸β‐氧化和线粒体融合参与胰高血糖素受体拮抗剂对糖尿病小鼠心脏微血管内皮细胞的保护作用

open access: yesJournal of Diabetes, Volume 15, Issue 12, Page 1081-1094, December 2023., 2023
Highlights Glucagon receptor (GCGR) monoclonal antibody (mAb) improves cardiac function and attenuates microvascular damage in db/db mice. GCGR mAb ameliorates the oxidative stress of cardiac microvascular endothelial cells in diabetic mice. GCGR mAb counteracts the diabetes‐induced upregulation of carnitine palmitoyltransferase 1B, optic atrophy type ...
Peng Wang   +6 more
wiley   +1 more source

Sensitivity of a Hymenoptera serological immunoglobulin (Ig)E assay for the diagnosis of venom hypersensitivity in dogs

open access: yesVeterinary Dermatology, Volume 34, Issue 6, Page 543-553, December 2023., 2023
Background – Hymenoptera envenomation with honey bee (Apis mellifera) and paper wasp (Polistes spp.) may cause life‐threatening anaphylaxis in dogs. In human patients, clinical history, intradermal testing (IDT) and measurement of allergen‐specific serological immunoglobulin (Ig)E (sIgE) are used to support a diagnosis of Hymenoptera venom ...
Hilary H. Chan   +3 more
wiley   +1 more source

Immunoglobulin E‐specific allergens against leaf in serum of dogs with clinical features of grass leaf allergy

open access: yesVeterinary Dermatology, Volume 34, Issue 5, Page 393-403, October 2023., 2023
Background – Grass leaf has been suspected to cause immunoglobulin (Ig)E‐mediated immediate hypersensitivity reactions both in humans and in dogs. However, most studies in this area are case control studies without in vitro data showing the involvement of IgE in the reaction.
Ken Mason, Janet Davies, Merja Ruutu
wiley   +1 more source

Equine allergic skin diseases: Clinical consensus guidelines of the World Association for Veterinary Dermatology

open access: yesVeterinary Dermatology, Volume 34, Issue 3, Page 175-208, June 2023., 2023
Abstract Background Allergic skin diseases are common in horses worldwide. The most common causes are insect bites and environmental allergens. Objectives To review the current literature and provide consensus on pathogenesis, diagnosis, treatment and prevention. Materials and Methods The authors reviewed the literature up to November 2022.
R. Marsella   +6 more
wiley   +1 more source

Efficacy of subcutaneous allergen immunotherapy in atopic dogs: A retrospective study of 664 cases

open access: yesVeterinary Dermatology, Volume 33, Issue 4, Page 321-e75, August 2022., 2022
Background –Canine atopic dermatitis (cAD) is an allergic skin disease affecting approximately 10% of dogs. Allergen immunotherapy (AIT) is currently the only treatment option able to induce tolerance to the causative allergens. Objective – To retrospectively establish the efficacy of AIT in atopic dogs.
Evelien E. M. Fennis   +6 more
wiley   +1 more source

Effects of SGLT2 inhibitors on patients with diabetic kidney disease: A preliminary study on the basis of podocyturia SGLT2抑制剂对糖尿病肾病患者的影响:基于尿足细胞的初步研究

open access: yesJournal of Diabetes, Volume 14, Issue 4, Page 236-246, April 2022., 2022
Highlights Diabetic kidney disease is a progressive disease with the pathology of glomerular damage and loss of podocytes. Sodium glucose cotransporter 2 inhibitors (SGLT2i) can be expected to decrease the amount of podocyte excretion. Male patients receiving SGLT2i have better diabetic kidney disease‐related parameters and podocyturia levels. Abstract
Emre Durcan   +13 more
wiley   +1 more source

Immunopathogenesis and immunotherapy of Culicoides hypersensitivity in horses: an update

open access: yesVeterinary Dermatology, Volume 32, Issue 6, Page 579-e156, December 2021., 2021
Culicoides hypersensitivity (CH) is a strongly pruritic dermatitis of horses, characterised histologically by mixed perivascular to diffuse cellular infiltrates of mononuclear cells and eosinophils, and caused by helper T cell (Th)2, immunoglobulin (Ig)E‐mediated reactions to antigens present in the saliva of biting Culicoides midges.
Eliane Marti   +7 more
wiley   +1 more source

Are psychiatric disorders associated with thyroid hormone therapy in adolescents and young adults with type 1 diabetes? 青少年和青壮年1型糖尿病患者的精神障碍与甲状腺激素治疗有关吗?

open access: yesJournal of Diabetes, Volume 13, Issue 7, Page 562-571, July 2021., 2021
Highlights Several psychiatric disorders were associated with levothyroxine therapy (LT4). Depression, anxiety disorders, and attention‐deficit/hyperactivity disorder showed the strongest relation to LT4. Thyroid autoimmunity itself (no LT4) was not associated with psychiatric disorders.
Alexander Eckert   +9 more
wiley   +1 more source

Reproducibility of serum testing for environmental allergen‐specific IgE in dogs in Europe

open access: yesVeterinary Dermatology, Volume 32, Issue 3, Page 251-e67, June 2021., 2021
Background – Serum testing for allergen‐specific immunoglobulin (Ig)E is commonly employed to identify allergens used for allergen‐specific immunotherapy in dogs, yet the reliability of results has been a matter of debate. Objective – The aim of this study was to evaluate the reproducibility of serum tests for environmental allergen‐specific IgE in ...
Katja N. Baumann   +4 more
wiley   +1 more source

Immunopathogenesis of the feline atopic syndrome

open access: yesVeterinary Dermatology, Volume 32, Issue 1, Page 13-e4, February 2021., 2021
Résumé Contexte Les maladies félines supposées d’origine allergique avec des phénotypes cliniques semblables, peuvent avoir de nombreuses pathogénies différentes sous jacentes. Le phénotype clinque, l’étiologie précise et l’immunopathogénie sous jacente doivent tous être considérés si des avancées veulent être faites dans ces domaines négligés de la ...
Richard Halliwell   +3 more
wiley   +1 more source

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