Results 11 to 20 of about 21,935 (162)
SARS‐CoV‐2 infection as cause of in‐utero fetal death: regional multicenter cohort study
ABSTRACT Objective Placental infection with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can lead to placental insufficiency and in‐utero fetal death (IUFD). The objective of this study was to confirm and quantify the extent to which fetoplacental infection with SARS‐CoV‐2 is a cause of fetal death.
M. Nkobetchou +9 more
wiley +1 more source
Successful surgical removal of a pheochromocytoma in a mare via trans‐costal approach
Abstract Background Pheochromocytomas have been previously reported in horses, but successful antemortem diagnosis and surgical removal without recurrence of clinical signs have not been described. Objective To report the clinical presentation, diagnostic evaluation, surgical technique, anaesthetic management and post‐operative care of a mare diagnosed
Thomas J. O'Brien +6 more
wiley +1 more source
Background – While the clinical features were described recently, the histopathological characterisation of trunk‐dominant canine pemphigus foliaceus (PF) is lacking, and whether it differs from classic facial or insecticide‐triggered PF is unknown. Hypothesis/Objectives – This study describes the histopathological findings of trunk‐dominant PF, and ...
Natalie Katharina Yvonne Gedon +6 more
wiley +1 more source
Canine melanocytes: Immunohistochemical expression of melanocytic markers in different somatic areas
Background – Melanoblasts originate in the neural crest from where they migrate to peripheral tissues and differentiate into melanocytes. Alteration during melanocyte development and life can cause different diseases, ranging from pigmentary disorders and decreased visual and auditory functions, to tumours such as melanoma.
Ilaria Porcellato +5 more
wiley +1 more source
Immunopathogenesis and immunotherapy of Culicoides hypersensitivity in horses: an update
Culicoides hypersensitivity (CH) is a strongly pruritic dermatitis of horses, characterised histologically by mixed perivascular to diffuse cellular infiltrates of mononuclear cells and eosinophils, and caused by helper T cell (Th)2, immunoglobulin (Ig)E‐mediated reactions to antigens present in the saliva of biting Culicoides midges.
Eliane Marti +7 more
wiley +1 more source
A case series of canine cutaneous inverted papilloma with one case showing evidence of recurrence
Background – This article describes a case of multiple, recurrent, cutaneous inverted papillomas (CIPs) in a German shepherd dog, combined with a retrospective follow‐up assessment of eight cases. Methods – A 3‐year‐old, black, female German shepherd dog presented with four rapidly growing, alopecic, domed, hyperpigmented, shiny nodules, compatible ...
Teresa M.S.A. Boehm +5 more
wiley +1 more source
Salivary gland hypofunction in KK‐Ay type 2 diabetic mice
Abstract Background Hypofunction of different organs in the body is associated with diabetes, including in the oral cavity. Diabetes is often associated with xerostomia, but the underlying mechanism is not well characterized. Thus, the mechanisms underlying diabetes‐induced xerostomia were investigated in this study in KK‐A y mice as an experimental ...
Takashi Munemasa +8 more
wiley +1 more source
First report of indolent cutaneous T‐cell lymphoma in a fennec fox (Vulpes zerda)
A 10‐year‐old fennec fox (Vulpes zerda) was presented for multifocal regions of chronic alopecia and crusting. Cutaneous lymphocytosis was diagnosed through histopathological examination and immunohistochemical investigation. Clonal rearrangement of the T‐cell receptor gamma locus supports that lymphocytosis in this case is an indolent lymphoma ...
Kristen L. Shekelle +5 more
wiley +1 more source
Background – Canine atopic dermatitis (cAD) is a chronic, inflammatory, multifactorial and pruritic disease. The presence of skin barrier impairment (e.g. filaggrin alterations), along with abnormal immune responses, can negatively impact cutaneous barrier function.
Wendie Roldan Villalobos +5 more
wiley +1 more source
Preliminary Studies of Neuropilin-1 Expression on HCC and Inhibitive Effect of Anti-NRP-1 Monoclonal Antibody on HCC Growth [PDF]
摘要 研究背景和目的 肝癌是世界上最常见的恶性肿瘤之一,男性与女性中肝癌诊断率分别为世界第五和第七,男性及女性肝癌相关死亡率在癌症相关死亡中分别居第二和第六。肝细胞癌占所有肝癌的70%-85%,其诊断和治疗取决于多方面因素——肿瘤的大小,范围,全身和肝功能情况。早期确诊的肝癌患者,才有可能接受肝脏切除或移植等治疗。然而仅有10%-30%的肝细胞癌患者适合根治性治疗,大多数肝细胞癌患者,确诊时已经处于中晚期,无法行根治性治疗,且预后较差。而传统的介入治疗、放化疗存在抗肿瘤效果较差、副作用大等缺点 ...
张亚飞
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