Results 1 to 10 of about 87 (65)
Zhongshan Daxue xuebao. Yixue kexue ban, 2006 [目的]探讨内皮祖细胞修复动脉内皮损伤的作用.[方法]建立大鼠颈总动脉内皮损伤模型,16只大鼠随机等分为内皮祖细胞移植组和对照组.体外诱导大鼠外周血单个核细胞为内皮祖细胞.在动脉损伤后,将5-溴脱氧尿苷标记的内皮祖细胞注入损伤动脉段,14 d后取损伤动脉段和对侧正常动脉段.采用病理学方法、免疫组织化学和图像分析技术评价内皮祖细胞的修复效果.[结果]内皮祖细胞移植组的损伤动脉段5-溴脱氧尿苷免疫组化为阳性.内皮祖细胞移植组损伤动脉段的新生内膜厚度较对照组明显减轻（43.5±5.5）μm vs（90.7 ...
徐明国 +6 more
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切应力对内皮祖细胞t-PA基因表达和小径人工血管移植通畅率的影响 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2007 【目的】研究切应力对内皮祖细胞组织纤溶酶原激活物(tissue-type plasminogen activator,t-PA)基因表达和种植内皮祖细胞小径聚氨酯人工血管移植通畅率的影响。【方法】诱导健康成人外周血的单个核细胞分化成为内皮祖细胞。种植内皮祖细胞到小径人工血管表面后,分为静态组、低切应力组(5dyn/cm2)、中切应力组(15dyn/cm2)和高切应力组(25dyn/cm2)4种不同处理组,用酶联免疫吸附法测定不同时间点培养液中t-PA的水平,并用荧光定量RT-PCR分析内皮祖细胞t ...
杨震 +7 more
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The effect of angiotensin (1-7) on bone marrow stem cells:adjunctive pharmacological therapy for cell transplantation in heart failure [PDF]
, 2008 Myocardial infarction [MI] is the major cause of death in western countries. The loss of cardiomyocytes and insufficient blood supply are the most frequent causes for the development of chronic heart failure [CHF]. Current therapy in patients after MI is
Qian, Cheng
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, 2021 目的探讨外周血白细胞端粒长度与慢性心力衰竭（CHF）发生风险的相关性。方法本研究招募了224例患者，根据左心室射血分数分为非CHF（Non-CHF）组（117例）和CHF组（107例），用实时荧光定量多聚核苷酸链式反应（ qPCR） 进行外周血白细胞端粒长度的测量。比较Non-CHF组和CHF组患者端粒长度，并采用二元 Logistic回归模型分析端粒长度与CHF发生风险是否相关。结果Non-CHF组和CHF组患者外周血白细胞端粒相对长度分别为0.9（0.64~1.18）、0.7（0.53~0.89 ...
吴智业 +5 more
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Zhongguo shiyan zhenduanxue, 2023 骨髓间充质干细胞(BMSCs)是一群具有自我更新能力并具有多项分化潜能的祖细胞，研究显示其能通过多种机制改善已经发生纤维化的肺内结构，恢复肺通气功能[1]，其作用机制可能与抑制上皮-间充质转化(EMT)，改善肺泡上皮损伤等多种途径有关[2-3]。本文就BMSCs在肺纤维化中抑制上皮-间充质转化的研究进展做一综述。
李鑫丽, 张春媚, 赵忠岩
doaj
Progress in functional mechanisms and biomarkers of miRNA related to Kawasaki disease [PDF]
, 2023 Kawasaki disease is an acute febrile exanthema pediatric disease with systemic vasculitis as the main lesion, which is the most common cause of acquired heart disease in children.
DUAN Junkai, FENG Jiali, PENG Yu
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Analysis of Characteristics and Influencing Factors of Hearing Impairment in Patients with Polycystic Ovary Syndrome [PDF]
, 2022 BackgroundHearing impairment in patients with polycystic ovary syndrome (PCOS) has been confirmed, However, the influencing factors of hearing impairment in PCOS patients have not been fully explained.ObjectiveTo explore the characteristics of hearing ...
XIE Zhijia, ZHANG Lei, CHEN Xin, CHANG Tao
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The study on the mechanism of topical propranolol gel in therapy of superficial infantile hemangiomas [PDF]
, 2015 目的：探讨外涂普萘洛尔凝胶对浅表型婴幼儿血管瘤（IHs）患儿血浆碱性成纤维生长因子（bFGF）、基质金属蛋白酶-9(MMP-9)、血管内皮生长因子（VEGF）、肾素和血管紧张素Ⅱ（ATⅡ）水平的影响。初步探讨普萘洛尔凝胶治疗婴幼儿血管瘤的可能机制，以寻找治疗婴幼儿血管瘤高选择性用药，减少不良反应的发生。 方法：选取2013年2月至2014年2月厦门大学附属东方医院普通外科接受普萘洛尔凝胶治疗的33例婴幼儿血管瘤患儿，采用Achauer分级标准评估疗效，酶联免疫吸附试验（ELISA）检测患儿治疗前 ...
唐玉娟
core
Roles of Sema3C on Breast Cancer Angiogenesis and Metastasis [PDF]
, 2012 神经系统的发育依赖于一系列导向系统的控制。近年来的研究结果表明，神经导向系统不仅调控神经系统的发育，在血管新生和肿瘤发展等方面也发挥着重要的调控作用。神经生长导向因子Class3semaphorins（Sema3s）是脊椎动物中semaphorin家族中唯一一个的分泌型亚族。在Sema3s家族中的大部分成员在肿瘤发展过程中起抑制作用，而Sema3C却可能是一个促进肿瘤发展的因子。目前对于Sema3C在肿瘤中的作用主要集中在对肿瘤迁移、侵袭的影响等方面，对于肿瘤血管新生的影响还未见报道 ...
叶丽颖
core
Recent Developments in Stem Cells from Human Exfoliated Deciduous Teeth in the Treatment of Non-oral Diseases [PDF]
, 2023 Stem cells from human exfoliated deciduous teeth (SHEDs) are odontogenic stem cells with strong proliferation ability and multilineage differentiation potential.
JIANG Zhihan, XU Ling
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