Anti-inflammatory effect of OEA,a PPAR-α agonist,in HUVECs [PDF]
, 2010 研究背景：在我国，随着生活水平提高和人口老龄化，心脑血管疾病发病率呈逐年上升趋势，并且患病年龄趋于年轻化，有关动脉粥样硬化药物的研究也成为药物研究的热点。TNF-α是一类具有广泛影响的有效促炎症性细胞因子，存在于AS的损伤部位，介导和放大了许多相互作用，导致炎症进展、斑块不稳定和促血栓形成倾向。本课题组先前的研究TNF-α诱导的内皮细胞粘附分子ICAM及VCAM的mRNA及蛋白表达都有明显升高，而OEA高、中、低剂量均可使其有不同程度的下降。探讨OEA对TNF-α导致的血管内皮细胞的炎症损伤的保护作用 ...
李刚
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Association between complete blood count-derived inflammatory indices and the risk and severity of erectile dysfunction, as well as their joint effects with age [PDF]
Objective To evaluate the association between complete blood count (CBC)-derived inflammatory indices and the risk and severity of erectile dysfunction (ED) among men in the Fangchenggang region of Guangxi, China, and to further explore the joint effects
Jialong LI +4 more
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Cloning and Expression Analysis of Edg Family Receptors during Early Chick Development [PDF]
, 2009 Edg（endothelialdifferentiationgene）受体家族属于G蛋白偶联受体亚家族，介导S1P（磷脂酸鞘氨醇，sphingosine-1-phosphate）和LPA（溶血磷脂酸，sysophosphatidicacid）信号，参与细胞增殖、迁移、分化、细胞骨架重组和细胞凋亡等细胞活动调节，在血管及神经发育、生殖、移植、免疫、损伤修复、肿瘤和自身免疫性疾病等生理病理过程中发挥作用。目前在人和小鼠中已发现八个Edg受体家族成员，根据它们结合的配体分子分为S1P亚家族（S1p1/Edg1、
易晓燕
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Zhongshan Daxue xuebao. Yixue kexue ban, 2016 摘 要:【目的】 探讨体外流体切应力对内皮祖细胞(EPC)再内皮化能力的影响及可能的分子机制?【方法】 入选10名排除心血管病危险因素?病史和临床证据的青年志愿者[(25.4 ± 6.6)岁],抽取外周血20 mL,采用密度梯度离心法分离提取EPC?在体外采用生理范围(15 dyn/cm2)流体切应力处理培养的EPC不同时间(0, 6, 12, 24 h),观察EPC体外的迁移?黏附能力的变化?通过建立裸鼠颈动脉拉脱损伤模型,观察流体切应力对志愿者EPC颈动脉内皮损伤修复能力的影响?用Realtime
doaj
Zhongshan Daxue xuebao. Yixue kexue ban, 2010 【目的】 观察一氧化氮(NO)信号途径在膜雌激素受体介导的内皮祖细胞(EPCs)增殖和凋亡中的作用65377; 【方法】 在培养的EPCs上,分别使用E2-BSA65380;或加雌激素受体阻断剂ICI 182,78065380;PI3K抑制剂LY294002和NOS抑制剂l-NAME,利用噻唑蓝(MTT)法检测细胞增殖活性(10组,n = 9),利用化学比色法测定NO的含量(6组,n = 6),Hoechst 33258染色观察EPCs凋亡(8组,n = 5 ...
doaj
[Experimental study of endothelial progenitor cells derived small extracellular vesicles for spinal cord injury repair in mice]. [PDF]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, 2021 Lin J, Huang T, Gao T, Zheng X.
europepmc +1 more source
Endothelial progenitor cells and chronic obstructive pulmonary disease: From basic research to clinical application. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue BanHe X, Zeng H, Chen Y.
europepmc +1 more source
Potential effect of endothelial progenitor cells on pentylenetetrazole-induced seizures in rats: an evaluation of relevant lncRNAs. [PDF]
J Zhejiang Univ Sci BAli SO, Shahin NN, Safar MM, Rizk SM.
europepmc +1 more source
[Research on tissue regeneration and engineered scaffold materials in prevention and treatment of lymphedema]. [PDF]
Zhongguo Xiu Fu Chong Jian Wai Ke Za ZhiYuan S, Deng C.
europepmc +1 more source
[Research progress on extracellular vesicles derived from platelet-rich plasma in tissue repair and regeneration]. [PDF]
Zhongguo Xiu Fu Chong Jian Wai Ke Za ZhiHan J, Cheng B.
europepmc +1 more source