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Association between complete blood count-derived inflammatory indices and the risk and severity of erectile dysfunction, as well as their joint effects with age [PDF]

open access: yes
Objective To evaluate the association between complete blood count (CBC)-derived inflammatory indices and the risk and severity of erectile dysfunction (ED) among men in the Fangchenggang region of Guangxi, China, and to further explore the joint effects
Jialong LI   +4 more
core   +1 more source

切应力对内皮祖细胞血管再内皮化能力的影响及机制

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2016
摘 要:【目的】 探讨体外流体切应力对内皮祖细胞(EPC)再内皮化能力的影响及可能的分子机制?【方法】 入选10名排除心血管病危险因素?病史和临床证据的青年志愿者[(25.4 ± 6.6)岁],抽取外周血20 mL,采用密度梯度离心法分离提取EPC?在体外采用生理范围(15 dyn/cm2)流体切应力处理培养的EPC不同时间(0, 6, 12, 24 h),观察EPC体外的迁移?黏附能力的变化?通过建立裸鼠颈动脉拉脱损伤模型,观察流体切应力对志愿者EPC颈动脉内皮损伤修复能力的影响?用Realtime
doaj  

膜雌激素受体介导的NO途径对EPCs增殖和凋亡的影响

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2010
【目的】 观察一氧化氮(NO)信号途径在膜雌激素受体介导的内皮祖细胞(EPCs)增殖和凋亡中的作用65377; 【方法】 在培养的EPCs上,分别使用E2-BSA65380;或加雌激素受体阻断剂ICI 182,78065380;PI3K抑制剂LY294002和NOS抑制剂l-NAME,利用噻唑蓝(MTT)法检测细胞增殖活性(10组,n = 9),利用化学比色法测定NO的含量(6组,n = 6),Hoechst 33258染色观察EPCs凋亡(8组,n = 5 ...
doaj  

Cloning and Expression Analysis of Edg Family Receptors during Early Chick Development [PDF]

open access: yes, 2009
Edg(endothelialdifferentiationgene)受体家族属于G蛋白偶联受体亚家族,介导S1P(磷脂酸鞘氨醇,sphingosine-1-phosphate)和LPA(溶血磷脂酸,sysophosphatidicacid)信号,参与细胞增殖、迁移、分化、细胞骨架重组和细胞凋亡等细胞活动调节,在血管及神经发育、生殖、移植、免疫、损伤修复、肿瘤和自身免疫性疾病等生理病理过程中发挥作用。目前在人和小鼠中已发现八个Edg受体家族成员,根据它们结合的配体分子分为S1P亚家族(S1p1/Edg1、
易晓燕
core  

[ROMO1 Promotes the Repair of Radiation-induced Skin Injury by Regulating Mitochondrial Function and Keratinocyte Proliferation]. [PDF]

open access: yesSichuan Da Xue Xue Bao Yi Xue Ban
Yang T   +8 more
europepmc   +1 more source

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