Results 21 to 30 of about 27,154,112 (122)
Abstract Objectives Neonates with critical congenital heart disease (CCHD) are at risk for adverse early brain development and long‐term neurodevelopmental sequelae. Insulin‐like growth factor‐1 (IGF‐1) and insulin‐like growth factor binding protein‐3 (IGFBP‐3) are essential contributors to brain growth and maturation.
M. Nijman +33 more
wiley +1 more source
近年研究提示由脂肪组织特异性表达的脂肪细胞因子一脂联素与糖尿病肾病有关。糖尿病是严重危害人们健康和生活质量的一种常见病、多发病,糖尿病肾病(DN)是严重影响预后的并发症之一。糖尿病肾病的发病与炎症及内皮功能受损密切相关。脂联素通过胰岛素敏感化、抗炎、抗氧化等途径对内皮起保护功能,同时是一种重要的负性炎性调节物质。血管细胞黏附分子(VCAM-1)及hsCRP是重要的炎症因子 ...
边芳, 杨秦予, 郭桂智
doaj
血管内皮是存在于血流与血管壁之间的一层上皮细胞,在血液与组织液之间起着天然屏障[1]。血管内皮还是人体最大的内分泌器官以及多种血管活性物质的靶器官,具有维持血液正常流动、调节血管的舒缩状态、抑制血小板聚集、抗炎等重要作用。在某些病理状态下,血管内皮容易受到各种理化因素的刺激而受损,引起内皮功能障碍。内皮细胞连接处有许多黏附分子,VE-cad是黏附连接的主要黏附分子 ...
张兴通, 王淼, 赵鹃
doaj
Summary Transcription factors of the CYCLING DOF FACTOR (CDF) family activate in potato the SP6A FT tuberization signal in leaves. In modern cultivars, truncated StCDF1.2 alleles override strict SD control by stabilizing the StCDF1 protein, which leads to StCOL1 suppression and impaired activation of the antagonic SP5G paralog. By using DAP‐seq and RNA‐
Maroof Ahmed Shaikh +6 more
wiley +1 more source
目的建立大鼠左颈总动脉与左侧颈外静脉吻合分流性肺动脉高压模型。方法成年雄性Wistar大鼠随机分为三组:吻合组(A组,n=15),结扎组(B组,n=15),正常组(C组,n=15)。饲养3月后测定血流动力学指标,右心室/左心室+室间隔质量比,肺组织切片病理变化,ELISA方法测定血浆ET-1浓度,荧光定量PCR测定肺组织表达内皮素-1mRNA的变化。结果与B,C两组相比,A组:右心室收缩压力明显升高,血清内皮素-1水平升高,荧光定量PCR结果显示A组内皮素-1mRNA的相对表达量是B组的2.601倍 ...
赵科研 +4 more
doaj
Relieving the transfusion tissue traffic jam: a network model of radial transport in conifer needles
Summary Characteristic of all conifer needles, the transfusion tissue mediates the radial transport of water and sugar between the endodermis and axial vasculature. Physical constraints imposed by the needle's linear geometry introduce two potential extravascular bottlenecks where the opposition of sugar and water flows may frustrate sugar export: one ...
Melissa H. Mai +5 more
wiley +1 more source
Background – Topical therapy is preferred for otitis externa (OE) in dogs, and otic products commonly contain glucocorticoids that can be systemically absorbed and possibly interfere with diagnostic tests such as intradermal testing (IDT). Hypothesis/Objectives – To determine the effect of a long‐lasting otic solution containing mometasone furoate (MF)
Jennifer L. Clegg +2 more
wiley +1 more source
【目的】观察阿拉瑞林对子宫内膜异位症大鼠异位病灶的抑制作用, 研究其对正位与异位子宫内膜雌激素受体 (ER)、孕激素受体(PR)的影响。【方法】27 只采用外科诱导法建立的子宫内膜异位症大鼠随机分成模型对照组和阿拉瑞林 (alarelin)治疗组, 模型组在同等条件下观察4 周, 阿拉瑞林组以alarelin 30 μg(kg·d)-1皮下注射4 周;治疗结束后, 用链霉素抗 生物素蛋白-过氧化物酶连接法(SP)行正位与异位内膜ER、PR 测定。【结果】阿拉瑞林组大鼠正位和异位子宫内膜生长活动 ...
郑澄宇 +4 more
doaj
Background – Mycophenolate is an immunomodulating agent successfully used for the treatment of moderate‐to‐severe atopic dermatitis (AD) in people. Mycophenolate is an effective steroid‐sparing treatment option for use in dogs with inflammatory skin diseases.
Michael Klotsman +5 more
wiley +1 more source
新生儿剥脱性皮炎是一种严重危及生命的疾病。国内记载在未使用抗生素以前,死亡率可达百分之五十,在抗生素运用之后,如果病人早期接受治疗,加强护理,多数可痊愈。 现将五例新生儿剥脱性皮炎的临床观察及护理体会小结如下: 一、临床资料(见表) 二、护理 1、预防感染:由于新生儿剥脱性皮炎,有不同程度的皮肤肿胀、糜烂、坏死、渗出及大量的剥脱,加之较大剂量激素的应用,
芦秀荣
doaj

