Role and mechanism of endoplasmic reticulum stress and NLRP3 inflammasome in acute kidney injury. [PDF]
Pei M, Deng K, Chen Y.
europepmc +1 more source
Endoplasmic reticulum stress-induced NLRP3 inflammasome activation as a novel mechanism of polystyrene microplastics (PS-MPs)-induced pulmonary inflammation in chickens. [PDF]
Lu H +6 more
europepmc +1 more source
[Huangpu Tongqiao Capsule improves cognitive impairment in rats with Wilson disease by inhibiting endoplasmic reticulum stress-mediated apoptosis pathway]. [PDF]
Zhang X +5 more
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颈交感神经干离断可通过抑制内质网应激降低大鼠脑缺血再灌注损伤
目的观察星状神经节阻滞(SGB)对大鼠脑缺血再灌注(I/R)损伤的影响及内质网应激(ERS)在其中发挥的作用。方法采用右侧颈交感神经干离断术(TCST)模拟星状神经节阻滞,将雄性SD大鼠分为5组:①假手术组(Sham);②脑缺血再灌注组(I/R);③TCST预处理+I/R组(I/R+TCST)④TCST预处理+ERS激动剂衣霉素(TM)+I/R组(I/R+TCST+TM);⑤ERS抑制剂4-苯基丁酸(4PBA)预处理+I/R组(I/R+4PBA)。术后24 h评估以下指标:①神经功能缺损评分 ...
张云飞, 辛楠, 田海涛
doaj
白内障是全球范围内致盲的重要原因之一。超声乳化术凭借创伤小、恢复快的优势,已成为治疗白内障的主流手术方式。然而,超声乳化术中参数的设置对眼内组织(尤其是角膜内皮和视网膜)的潜在损伤备受关注。本文系统分析了超声乳化术中3个核心参数(超声频率、灌注瓶高、超声能量)对眼内组织的影响机制及其相互作用。高频超声提高了乳化效率并缩短手术时间,但伴随更显著的热效应,尤其当术中结合高能量输出时,会明显加剧角膜内皮细胞的热损伤风险。高瓶高在维持前房稳定的同时,也增加了机械性剪切应力和湍流,对内皮细胞产生额外的物理损伤 ...
罗开杰, 仲苏鄂
doaj
[The role and mechanism of chemokine network in promoting osteoarthritis progression by regulating synovial macrophage heterogeneity]. [PDF]
Lin Y, Wu L, Chen Q, Shen B.
europepmc +1 more source
[Effects of celastrol on autophagy and endoplasmic reticulum stress-mediated apoptosis in a mouse model of nonalcoholic fatty liver disease]. [PDF]
Tian T +5 more
europepmc +1 more source
[Spatial omics in pulmonary fibrosis: advancing mechanistic insights and therapeutic strategies]. [PDF]
Peng Y, Xie Y, Yang F, Qiao X, Tian Y.
europepmc +1 more source
[Single-cell RNA sequencing of B cells reveals molecular typing in Sjögren syndrome]. [PDF]
Lin W +6 more
europepmc +1 more source
[Role of the TGF<b>-β</b>1 signaling pathway in modulating in vivo adaptation of vascular grafts]. [PDF]
Zhang L +6 more
europepmc +1 more source

