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程序性细胞死亡在肺缺血再灌注损伤中的研究进展

open access: yesZhongshan Daxue xuebao. Yixue kexue ban
肺移植(LTx),是治疗终末期肺疾病(ESLD)唯一有效的根治性治疗手段,适用于药物和其他手术治疗无效的晚期肺病患者,可显著改善患者预后。但LTx仍面临诸多挑战,如缺血再灌注损伤(IRI)、长期生存率低等。改善肺IRI对移植术后肺功能的恢复和患者预后有重要意义。肺IRI是指肺组织经历血流中断(缺血)后恢复供血(再灌注)时,反而加重的组织损伤和炎症反应。IRI是导致原发性移植物功能障碍(PGD)的重要病理生理基础,其损伤机制复杂多样,涉及多种细胞死亡的激活。程序性细胞死亡(PCD)是细胞受基因调控发生的 ...
虞燕青, 孙煦勇
doaj  

[Advances in liver transplantation technology]. [PDF]

open access: yesZhonghua Gan Zang Bing Za Zhi
Zhu ZJ.
europepmc   +1 more source

[Helicid alleviates depression-like behavior in rats with chronic unpredictable mild stress through the NCALD/sGC/cGMP/PKG axis]. [PDF]

open access: yesNan Fang Yi Ke Da Xue Xue Bao
DU X   +8 more
europepmc   +1 more source

[Efficacy and safety of mechanical thrombectomy beyond 24 to 72 hours in acute ischemic stroke patients with large vessel occlusion]. [PDF]

open access: yesZhejiang Da Xue Xue Bao Yi Xue Ban
Jiang X   +8 more
europepmc   +1 more source

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