Results 121 to 130 of about 17,692 (195)
AAZ2 induces mitochondrial-dependent apoptosis by targeting PDK1 in gastric cancer. [PDF]
J Zhejiang Univ Sci B, 2023 Li Y +11 more
europepmc +1 more source
[Cannabidiol inhibits neuronal endoplasmic reticulum stress and apoptosis in rats with multiple concussions by regulating the PERK-eIF2α-ATF4-CHOP pathway]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoYang Y +7 more
europepmc +1 more source
[Inhibitory effect of low-intensity pulsed ultrasound on apoptosis of splenic lymphocytes in septic rats]. [PDF]
Nan Fang Yi Ke Da Xue Xue Bao, 2023 Tang W +5 more
europepmc +1 more source
MicroRNA-4279通过靶向核心启动子区域上调Notch-1基因表达进而抑制细胞凋亡
Zhongshan Daxue xuebao. Yixue kexue ban, 2015 摘 要: 【目的】 寻找与Notch-1基因核心启动子结合的microRNA(miRNA)并阐明其调控功能,研究免疫细胞肿瘤的发生发展机制?【方法】 首先使用生物信息学手段筛选与Notch-1基因核心启动子区域结合的miRNA,进而利用荧光素酶报告系统对其调控作用进行实验验证;通过突变核心启动子上的结合位点进一步确定该miRNA特异性靶向基因核心启动子区域?检测转染该miRNA后H9细胞中Notch-1的mRNA与内源蛋白表达水平?另外通过转染该miRNA并用H2O2诱导凋亡 ...
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HDAC1 overexpression inhibits steroid-induced apoptosis of mouse osteocyte-like MLO-Y4 cells by inducing SP1 deacetylation. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoZhang S +5 more
europepmc +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2009 【目的】 探讨和厚朴酚(HNK)对白血病细胞系U937细胞增殖和凋亡的影响65377;【方法】 将U937细胞和正常外周血单核细胞分别与HNK共培养,Hoechst33342荧光染色检测细胞凋亡形态,用噻唑蓝比色法(MTT)检测HNK对细胞增殖的抑制作用;流式细胞仪检测凋亡;罗丹明123检测线粒体膜电位;Caspase3/7活性检测试剂盒检测Caspase3/7活性;荧光定量PCR(FQ-PCR)检测Caspase-365380;Caspase-7 mRNA水平变化65377;【结果 ...
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[Mechanism by which mycobacterial antigen 85B inhibits autophagy and promotes apoptosis in Hodgkin lymphoma cells]. [PDF]
Zhongguo Dang Dai Er Ke Za ZhiCheng YF +6 more
europepmc +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2016 【目的】探讨IL-22对类风湿关节炎（RA）成纤维样滑膜细胞（FLS）凋亡的影响。【方法】收集行关节置换术或关节镜下滑膜切除术患者的滑膜组织，组织块法培养FLS。利用荧光定量RT-PCR（qRT-PCR）检测Bcl-2 mRNA和Bcl-XL mRNA、Western Blotting检测Bcl-2蛋白在RA、骨关节炎（OA）和创伤（Trauma）患者中FLS的表达水平。将RA-FLS以一氧化氮（NO）供体硝普钠（SNP）和/或重组人源性IL-22（rhIL-22）等处理24 h，流式细胞术分析检测凋亡。
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