Results 141 to 150 of about 17,692 (195)

桂皮酸诱导Ｂｅｌ－７４０２人肝癌细胞凋亡的作用及机制

Zhongshan Daxue xuebao. Yixue kexue ban, 2013
【目的】 通过检测不同浓度的桂皮酸对人肝癌Ｂｅｌ－７４０２细胞生存率及凋亡的影响，明确中药桂皮酸诱导该肿瘤细胞凋亡的作用和机制。【方法】 采用ＭＴＴ法检测０、１、３、５和１０ ｍｍｏｌ／Ｌ桂皮酸对正常肝细胞ＣＬ４８及人肝癌细胞Ｂｅｌ－７４０２生存率的影响；采用ＰＩ／ＡｎｎｅｘｉｎⅤ双染法检测０、１、３、５和１０ ｍｍｏｌ／Ｌ桂皮酸对Ｂｅｌ－７４０２细胞凋亡作用的影响；应用Ｗｅｓｔｅｒｎ－ｂｌｏｔ技术检测不同浓度桂皮酸对Ｂｅｌ－７４０２细胞中Ｂａｘ、ｃｙｔｏｃｈｒｏｍｅ ｃ、ｃａｓｐａｓｅ ８ ...
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果蝇凋亡检测—Caspase-3抗体染色法及TUNEL法 [PDF]

, 2019
松灵 张, 春霖 路, 晓林 秘
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[Monotropein improves motor function of mice with spinal cord injury by inhibiting the PI3K/AKT signaling pathway to suppress neuronal apoptosis]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Chen Y, Xiao L, Ren L, Song X, Li J, Hu J.   +5 more
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A novel bakuchiol aminoguanidine derivative induces apoptosis in human triple-negative breast cancer cells. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Zhang Z, Zhu J, Wang J, Chen J, Pang Y, Wu C.   +5 more
europepmc   +1 more source

[High homocysteine level promotes autophagy and apoptosis of mouse hippocampal HT22 cells through the Notch1/Hes1 signaling pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2023
Zhang J, He J, Mi X, Xu X, Tian Y, Yan R.   +5 more
europepmc   +1 more source

蛋白酶体抑制剂MG132对Raji细胞凋亡、细胞周期及UBE1基因表达的影响

Zhongshan Daxue xuebao. Yixue kexue ban, 2011
【目的】 探讨蛋白酶体抑制剂MG132对人Burkitt's淋巴瘤Raji细胞凋亡细胞周期及泛素活化酶(UBE1)基因表达的影响【方法】 5 μmol/L的MG132处理Raji细胞24 h,形态学观察细胞生长情况;流式细胞术Annexin V-FITC/PI双染法分析细胞凋亡PI单染法分析细胞周期;荧光定量RT-PCR检测UBE1 基因mRNA表达, Western blot 检测UBE1 蛋白表达【结果】 MG132处理组细胞生长缓慢,死亡及凋亡多见,细胞凋亡率(26.06 ± 1.10 ...
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一个人类凋亡相关新基因<em>TFAR15</em>的cDNA克隆化与表达 [PDF]

, 1999

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[<i>Gynostemma pentaphyllum</i> ethanol extract ameliorates motor dysfunction in a Parkinson<b>'</b>s disease mouse model through inhibiting neuronal apoptosis]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Zhao T, He L, Yan S, Fan P, Zhang C, Zeng L.   +5 more
europepmc   +1 more source

[TRAF6 promotes Bacillus Calmette-Guérin-induced macrophage apoptosis through the intrinsic apoptosis pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2022
Ma Q, Liu L, Yu J, Gong Z, Wang X, Wu X, Deng G.   +6 more
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靶向β2-肾上腺素受体抗骨肉瘤的实验研究

Zhongshan Daxue xuebao. Yixue kexue ban, 2016
摘 要: 【目的】 探索靶向β2-肾上腺素受体诱导骨肉瘤细胞凋亡的作用及相关分子机制?【方法】 利用MTT法检测靶向β2-肾上腺素受体对骨肉瘤细胞的生长抑制作用,流式细胞仪检测细胞周期阻滞及凋亡,Western blot法检测β2-肾上腺素受体抑制剂ICI118,551处理后相关信号通路的变化?【结果】 β2-肾上腺素受体抑制剂对骨肉瘤细胞的生长抑制作用,流式细胞仪检测结果证明ICI118,551可显著诱导骨肉瘤细胞周期阻滞及凋亡,以p-ERK蛋白水平表达变化最为显著?【结论】 靶向β2 ...
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