Results 21 to 30 of about 157,764 (151)
Rare Metals, Volume 45, Issue 3, March 2026.ABSTRACT Skin wound injuries are often accompanied by bacterial infections and severe inflammation. Especially, M1‐type macrophages at the wound site can trigger a cascade of inflammatory responses, mediating a vicious cycle of inflammation. Meanwhile, hypoxia further exacerbates vascular damage and constriction in the wound microenvironment, thereby ...
Xianfeng Wang +6 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2014 人体的抗凝系统主要有抗凝血酶（antithrombin,AT）系统（包括抗凝血酶和肝素,主要抑制具有丝氨酸蛋白酶活性的凝血因子,如:FXa,凝血酶等）和蛋白C系统（包括蛋白C,蛋白S,血栓调节蛋白,内皮细胞蛋白C受体等,主要灭活凝血因子Ⅴ和Ⅷ等 ...
李正民 +3 more
doaj
Multi‐Functional S‐HA/ASTA NPs Coating on Biodegradable ZE21B Alloy for Cerebrovascular Applications
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Magnesium (Mg) and its alloys have attracted extensive attention of researchers in the field of cerebrovascular implants due to their good mechanical properties and biosafety. However, rapid degradation and delayed endothelialization pose challenges. To address these issues, this study introduces a multifunctional composite coating.
Aqeela Yasin +4 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2011 目的探讨遗传性凝血因子V（FV）、X（FX）和XI（FXI）缺陷及FV和凝血因子VⅢ（FVⅢ）联合缺陷（F5F8D）患者的血浆凝血因子活性、凝血酶生成曲线各参数和临床出血症状之间的关系。方法采集遗传性FV（n=24）、FX（n=14）和FXI（n=18）缺陷及F5F8D（n=8）患者及携带者的外周血进行常规出凝血检查及自动校正凝血酶曲线法凝血酶生成试验。结果凝血酶生成曲线的各项参数与FV促凝活性（FV:C）及FX促凝活性（FX:C）存在双曲线趋势关系 ...
黄丹丹 +9 more
doaj
Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang +9 more
wiley +1 more source
体外血栓形成后血液的流变性变化及体外血栓形成试验的规范化操作
, 2008 目的:观察体外模拟血栓形成后剩余血液的流变学变化,并探讨体外血栓形成试验的规范化操作。方法:采用30例健康人静脉血液,一部分抗凝后测定血液流变学指标和血细胞计数,另一部分不抗凝,于Chandler环内模拟血栓形成后,再测定剩余血液的血细胞计数及流变学指标,包括血液表观粘度、红细胞聚集指数、红细胞变形指数、血小板最大聚集率、血小板粘附率和血浆纤维蛋白原含量等。结果:体外模拟血栓形成后剩余血液的表观粘度,血小板计数、白细胞计数及纤维蛋白原含量均显著降低(P0.05)。结论 ...
钱民全, 马鲁波, 刘剑刚
core +2 more sources
Veterinary Dermatology, Volume 36, Issue 4, Page 474-484, August 2025.Background – Sporotrichosis is a chronic, mycotic infection caused by fungi of the genus Sporothrix. Zoonotic sporotrichosis occurs mainly through S. brasiliensis transmission, resulting from the organism's traumatic introduction via scratches or bites, or contact with exudate from contaminated cats.
Steffanie Amadei +6 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2010 目的研究白树花多糖硫酸酯的抗凝血效果及抗凝血机理,为制备合成高效、安全的多糖硫酸酯抗凝剂提供实验依据。方法将可食用的白树花真菌进行发酵,提取水溶性多糖,采用氯磺酸-吡啶法进行硫酸酯化修饰,获得水溶性的白树花多糖硫酸酯。通过测定APTT、TT、凝血因子活性对白树花硫酸酯的抗凝血效果及抗凝血机理进行评估和探讨。结果对正常人血浆进行的抗凝血实验表明,白树花多糖硫酸酯具有明显的抗凝血活性,在520mg/L的浓度下即可发挥效果,在1020mg/L浓度时,相当于15020U肝素的抗凝血效果;抗凝血机理研究结果表明 ...
杨曦明 +4 more
doaj
Zhongguo shiyan zhenduanxue, 2007 目的探讨土鳖虫溶栓酶的抗凝血和抗血栓作用。方法给药后检测凝血时间、凝血酶原时间、血纤维蛋白原含量、血凝块溶解率。用体内、外血栓形成溶解实验检测抗血栓作用。结果土鳖虫溶栓酶0.25、0.5、1.0 mg/kg能明显延长小鼠凝血时间、大鼠凝血酶原时间,降低大鼠血纤维蛋白原含量,增加血凝块溶解率,延长大鼠颈动脉血栓形成的时间,缩短大鼠体外血栓长度,减轻血栓的湿重及干重。结论土鳖虫溶栓酶具有抗凝血和抗血栓作用。
王征, 陈晓光, 吴岩
doaj
Linchuang shenzangbing zazhi, 2018 血液净化是肾衰竭患者重要的肾脏替代治疗方式。在实施血液净化的过程中,血液和人工材料表面接触而导致凝血级联反应的激活,造成滤器和管路凝血[1]。通过对血液进行抗凝,可有效避免凝血的发生,保证血液净化顺利实施。不同的抗凝方式由于其抗凝机制差异,存在不同的适应症及禁忌症。选择恰当的抗凝方式是安全有效开展血液净化治疗的前提 ...
赵宇亮, 买红霞, 付平
doaj