Results 31 to 40 of about 3,161 (182)
Policy Studies Journal, Volume 53, Issue 3, Page 681-700, August 2025.Abstract OECD countries are grappling with a policy design dilemma, as they strive to balance fiscal sustainability with the increasing demands on the welfare state. This study introduces a new perspective on policy design that integrates the two elements of “social cohesion,” comprising government trust and civic engagement.
Jiwon Kim
wiley +1 more source
Whether therapeutic drug monitoring is necessary for linezolid? [PDF]
, 2016 利奈唑胺非肝药酶代谢,约35%以原型经肾排泄,说明书提示其浓度受其他药物影响轻微,肾功能不全患者无需调整剂量,但临床研究表明肾功能不全患者利奈唑胺所致血小板减少症或贫血发生率增高与利奈唑胺高暴露相关,且利奈唑胺与某些药物存在的相互作用可显著影响其血药浓度、利奈唑胺的血药浓度在危重症患者中个体差异大,应进行血药浓度监测。Linezolid is not metabolized by CYP450 s and only approximately 35% of the prototype was ...
余剑华, 卢志品, 曹伟
core
Influences on cannabis policy design and adaptation in the American states
Policy Studies Journal, Volume 53, Issue 3, Page 723-746, August 2025.Abstract Despite federal prohibitions, three‐quarters of states had implemented medical marijuana laws (MML) and one‐third had implemented recreational cannabis laws (RCL) by 2020. State policy designs varied considerably, and we focus on policy development and maturation in policy implementation, examining factors influencing design features of policy
Grant W. Neeley +1 more
wiley +1 more source
‘How Does Living in Institution Impact Young Lives?’—Insights From Young People in Ci'aiyuan
Children &Society, Volume 39, Issue 4, Page 760-769, July 2025.ABSTRACT Institutional care often carries a negative reputation due to its perceived adverse effects on children and young people. However, it remains a significant form of alternative care in China. In Xiangxi, childcare institutions, known as ci'aiyuan, have been further expanding by involving wider populations in recent years.
Shian Yin
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2013 目的利用结核分支杆菌噬菌体裂解法检测结核杆菌对利福平、异烟肼、链霉素敏感性。方法选用传统方法判定为利福平、异烟肼、链霉素的耐药或敏感菌株,采用噬菌体裂解法检测其对以上三种药物的敏感性,对比其特异性和敏感度。结果运用噬菌体裂解法检测结果显示,异烟肼药物浓度为1μg/ml时,其灵敏度为87.0%,特异度为93.3%,与传统方法的符合率为92.0%;链霉素药物浓度为4μg/ml时,其灵敏度为96.2%,特异度为92.0%,与传统方法的符合率为92.9%;利福平药物浓度为5μg/ml时,其灵敏度为91.4 ...
于宏波, 宋阳, 齐红, 韩忠波
doaj
野生动物学报, 2021 为做好高龄（年龄大于30岁）大熊猫（Ailuropoda melanoleuca）的饲养管理，提高圈养大熊猫种群福利及维持种群整体健康水平，通过调整成都大熊猫繁育研究基地3例高龄大熊猫的饲养管理策略，定量分析了调整前后大熊猫的体重、粪便量。结果表明：经过调整饲养管理方案后，3只高龄大熊猫中的2只体重增加显著 ...
彭文培谢意黄祥明吴孔菊杨奎兴王树群李翰
doaj
Multicolor Melting Curve Analysis-based on Detection of Pyrazinamide-Resistant Mycobacterium tuberculosis [PDF]
, 2017 结核病是由结核分枝杆菌感染人体的慢性传染性疾病。2015年新增患病人数高达1040万，有140万人死于结核病。在众多治疗结核病药物中，吡嗪酰胺是较早发现的一线抗结核药物之一。在酸性环境下，吡嗪酰胺可以抑制巨噬细胞内半休眠结核分枝杆菌。随着吡嗪酰胺广泛使用，耐受吡嗪酰胺的结核病危害面广，因此吡嗪酰胺耐药突变检测的研究急需开展。针对上述问题，本文利用探针熔解曲线分析技术对结核分枝杆菌吡嗪酰胺耐药突变检测展开研究。 第一章绪论，首先简要概述现今世界结核病概况，再介绍耐药结核病诊断和治疗的方法 ...
李梓
core
What Do People Want From a Welfare System? Conjoint Survey Evidence From UK Adults
Poverty &Public Policy, Volume 17, Issue 2, June 2025.ABSTRACT What do people want from a welfare system? Previous research has suggested a list of desiderata, such as that the system: reduces poverty; reduces inequality; improves mental and physical health; costs little; and rewards only the deserving. How do these different features trade off against one another to determine overall desirability?
Daniel Nettle +3 more
wiley +1 more source
基因芯片技术在分枝杆菌菌种鉴定和结核耐药性检测中的应用及评价
Zhongguo shiyan zhenduanxue, 2015 目的探讨基因芯片技术在结核病快速诊疗中的应用价值。方法对抗酸染色涂片阳性的肺结核患者痰标本同时进行基因芯片菌种鉴定和BACTEC MGIT 960培养,对结核阳性的样本分别用以上两种方法检测利福平和异烟肼的耐药性。以培养法为参考方法,评价基因芯片法菌种鉴定和耐药检测的敏感度、特异度和符合率。采用Kappa检验分析两种方法的一致性。结果 656例涂片阳性的患者中,两种方法各检出非结核分枝杆菌21例,符合率为100%。耐药性检测发现,基因芯片对利福平的敏感度为87.8%（86/98）,特异度为96.0 ...
李晓非 +4 more
doaj
目的探讨喀什地区神经型布鲁氏菌病的临床特征，提高诊疗水平。方法对2019年12月至2024年1月喀什地区第一人民医院收治的18例神经型布鲁氏菌病患者的临床资料进行回顾性分析。结果18例神经型布鲁氏菌病患者中，男性9例，女性9例，中位年龄36（17~54.5）岁。所有患者均有布鲁氏菌病流行病学史。诊断为脑膜脑炎12例，脑膜炎5例，脑炎1例。其中2例患者合并脊髓膜炎。2例患者合并骨关节炎，1例患者合并附睾炎。最常见的临床表现是头痛、发热、乏力。虎红平板试验（RBPT）及试管凝集试验（SAT ...
买买提艾力·吐尔逊 +6 more
core +1 more source