Results 81 to 90 of about 4,207 (149)
Zhongguo shiyan zhenduanxue, 2009 目的探讨前列腺干细胞抗原（PSCA）在小鼠前列腺癌（PCa）中的表达及意义。方法采用免疫组织化学（IHC）链霉菌过氧化物酶法（SP法）检测6例荷瘤小鼠前列腺癌石蜡包埋标本。结果PSCA在荷瘤小鼠PCa组织中表达阳性率为100%,其中强阳性率为83.3%。PSCA在小鼠PCa组织主要表达于癌细胞,细胞间质和肌肉组织均无表达。结论可以利用前列腺癌荷瘤小鼠进行PSCA在PCa的诊断、免疫治疗及判断预后方面动物实验研究。
杨轶凡, 曹霞, 谷欣权, 孔祥波
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Heterogeneous nuclear ribonucleoprotein H1 and its function in tumor development and metastasis [PDF]
Heterogeneous nuclear ribonucleoprotein (hnRNP) and heterogeneous nuclear RNA (hnRNA) form complexes that regulate RNA splicing and transportation. hnRNPH1 is a member of the hnRNP family of proteins and plays an important role in physiological processes,
FAN Zhisong, FENG Li, ZHANG Zongwen
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Evaluation of short⁃term efficacy of precision immunotherapy in prostate cancer patients and construction of a personalized prediction model based on PD⁃L1/TMB [PDF]
Objective To evaluate the short⁃term efficacy of programmed death⁃ligand 1（PD⁃L1）inhibitors in patients with prostate cancer and to construct an individualized predictive model based on PD⁃L1 expression levels and tumor mutational burden（TMB）to predict ...
HUANG Yiming，CHEN Zhibin，LYU Tianbing，LI Xiaorong
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Zhongguo shiyan zhenduanxue, 2012 由于人口老龄化的增加及饮食结构的变化,前列腺癌的发病率及死亡率居高不下[1],而早期诊断、早期发现,才能及时治疗,才能提高生活质量延长生命。随着我国对前列腺癌的诊断技术的提高和发展,医学研究者在基础和临床研究上有了长足的进步,特别是确诊率显著提高。众所周知前列腺特异抗原（PSA）、血清游离PSA（f PSA）与总PSA（tP-SA）的比值（f/t ...
秦海秋
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Effect of EphA2 Transfection on Proliferation and Invasion Activities of Prostate Cancer LNcap Cells [PDF]
, 2011 目的 本实验试图用外源基因EphA2转染LNcap细胞，探讨EphA2对前列腺癌LNcap细胞增殖、迁移、侵袭活性的影响。 方法 构建重组pcDNA3.1(+)-EphA2，转染LNcap细胞并经G418筛选出稳定转染株。实验分3组：（1）空白对照组：激素依赖性前列腺癌LNcap；（2）阴性对照组：转染空载质粒pcDNA3.1(+)的LNcap-pcDNA3.1(+)；（3）实验组：转染pcDNA3.1(+)-EphA2的LNcap稳定表达株LNcap-EphA2。RT ...
黄燕
core
Innovations and Challenges in Molecular Probe-Based Precision Theranostics for Genitourinary System Tumors [PDF]
Genitourinary system tumors, as a major clinical challenge posing a serious threat to human health, urgently require breakthroughs in the construction of a precision diagnosis and treatment system.
Mingwei SUN, Pengyu GUO, Wanhai XU
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前列腺癌骨转移患者血清PSA、ALP及ICTP的表达及临床意义
Zhongguo shiyan zhenduanxue, 2012 目的探讨血清中PSA、ALP及ICTP与前列腺癌骨转移的关系以及对前列腺骨转移的诊断意义。方法我院泌尿科确诊的98例前列腺癌患者,根据骨显像将98例前列腺癌患者分对照组（非骨转移）45例和观察组（骨转移）53例,采用化学发光免疫分析法和ELISA检测两组患者血清中PSA、ALP及ICTP的表达,分析ALP、PSA及ICTP与前列腺癌骨转移的关系及对骨转移的诊断价值。结果观察组ALP、PSA及ICTP明显高于对照组（P20μg/L为临界值其灵敏度、特异性和准确性分别为96.2%（51/53）、60.0 ...
李建, 巫骏川, 陈爽, 万子杨
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Diagnostic value of 18F-PSMA-1007 PET/CT combined with prostate specific antigen derived indicators in gray area prostate cancer. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2023 Guo S +5 more
europepmc +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2013 【目的】采用磁共振弥散加权成像比较绝对表观弥散系数(ADC)值及标准化ADC值在鉴别移行带前列腺癌及间质为主增生结节的效能?【方法】 55例临床怀疑前列腺癌的男性患者行MRI平扫及弥散加权成像检查,使用b值为0?1 000 s/mm2?所有患者在MR检查后1个月内行经直肠超声引导下前列腺穿刺活检?分别比较外周带前列腺癌及移行带前列腺癌的ADC值及标准化ADC值,移行带前列腺癌与间质为主增生结节的ADC值及标准化ADC值 ...
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Zhongguo shiyan zhenduanxue, 2016 前列腺癌是欧美国家最常见的恶性肿瘤之一,在美国男性肿瘤患者的死因中位于第2位[1]。随着国人生活水平的提高和平均年龄的增加,我国前列腺癌的发病率近年来呈上升趋势。为了解新疆维汉两族前列腺癌患者的患病特点,发病趋势及各族患者组织标本中AMACR表达的情况 ...
屈小骅 +3 more
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