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Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2012
背景与目的肿瘤的多药耐药性（multidrug resistance, MDR）是导致肺癌化疗失败的主要原因，长春瑞滨（Vinorelbine，诺维本，NVB）是治疗非小细胞肺癌最有效的化疗药物之一，本研究旨在建立人肺腺癌Anip973/NVB耐药细胞的动物模型，并初步探讨其耐药机制。方法采用皮下注射法建立人肺腺癌Anip973细胞和耐药细胞Anip973/NVB的裸鼠移植瘤模型，分成Anip973治疗组、Anip973对照组、Anip973/NVB治疗组、Anip973/NVB对照组 ...
Meng Wang +5 more
semanticscholar +1 more source

Beneficial effects of silibinin against the progression of metabolic syndrome, increased oxidative stress, and liver steatosis in Psammomys obesus, a relevant animal model of human obesity and diabetes (在一种与人类肥胖以及糖尿病相关的动物模型肥沙鼠中，水飞蓟素具有拮抗代谢综合征进展、拮抗氧化应激增加以及拮抗肝脏脂肪变性的有益作用)