Metabolic labeling of Porphyromonas gingivalis and comparison of two fluorescent probes for in vivo imaging [PDF]
Objective To investigate the impact of metabolic labeling on Porphyromonas gingivalis (Pg) and compare the imaging effects of two fluorescent probes. Methods This study was reviewed by the unit Ethics Committee and was approved by the Experimental Animal
CHENG Xinyi, ZOU Peihui, LIU Jia, LUAN Qingxian
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Targeting folate cycle enhances effects of cancer immunotherapy by modulating myeloid-derived suppressor cells [PDF]
Objective·To explore the regulatory mechanism of folate cycle metabolism in the immunosuppressive effect of myeloid derived suppressor cells (MDSCs).Methods·Bone marrow cells were isolated from C57BL/6 mice and cultured in RPMI 1640 medium supplemented ...
HE Rui, WANG Jing, YAN Kepeng
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Ameliorative Effects of Polygonatum kingianum Polysaccharides on Lipid Metabolism Disorders and Brain Function Impairments in Obese Mice [PDF]
To study the effects of Polygonatum kingianum polysaccharides (PKP) on lipid metabolism disorders and brain function impairments in obese mice, the obese mice were treated with PKP, prepared by enzyme-assisted extraction, for 12 weeks.
XU Yuncong, YAN Qiaojuan, ZHU Chunhua, YANG Shaoqing, LI Houjiang, JIANG Zhengqiang
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Relationship between the Degeneration and Regeneration of Neuromuscular Junction and Wound Age during the Repair of Mouse Skeletal Muscle Contusion [PDF]
Objective To investigate the morphological changes in the degeneration and regeneration of neuromuscular junctions (NMJ) during the repair of mouse skeletal muscle contusion and discuss the correlation between the degeneration and regeneration of NMJ and
SUN Ying-fu, ZHANG Meng-zhou, WANG Shuai,et al.
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束缚和异氟烷麻醉对大鼠心率变异性及HPA轴影响的比较 [PDF]
目的为了观察束缚固定和异氟烷(流量:0.8 L,浓度:1.5%)麻醉状态中大鼠的心率变异性的变化;并通过比较9天每天30 min束缚干预和异氟烷麻醉对大鼠的体重、痛阈以及与HPA轴相关激素的影响,来评估长期使用异氟烷麻醉和束缚固定对大鼠应激程度的影响,选择更适宜的大鼠固定方法,为基础医学的实验方法提供重要的参考。方法 SD大鼠随机分为3组:空白组,束缚组,异氟烷麻醉组。急性实验通过记录大鼠心电图15 min,观察束缚固定和异氟烷麻醉情况下大鼠心率,心率变异性的变化。慢性实验中比较连续干预9天(30 ...
何伟 +6 more
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The Marketing System Analysis Of Xiamen ShouHuShen Working Dog Co.,Ltd. [PDF]
随着社会发展,国民经济持续增长,人民生活水平和生活质量不断提高,我国居民的物质及文化生活在经济的增长过程中获得了极大的丰富,对于情感及精神生活的追求被放到了前所未有的高度。宠物经济应运而生,作为一个刚起步的产业,从国家制度到企业内部都缺乏理论指导,相关人员更多是参考过往经验与国外案例。时代背景与国情的不同,令中国宠物经济的发展处于完全由市场调控的状态。 宠物经济产业链的各个环节,入行门槛低、经营规模小、技术力量薄弱、单位利润高的特点,吸引广大中小投资人进入这个新领域,试图分食一块蛋糕。软 ...
邵壹鑫
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Effect of ginkgolide B on hepatic ischemia-reperfusion injury in mice with fatty liver disease and its mechanism [PDF]
Objective To investigate the effect of ginkgolide B on hepatic ischemia-reperfusion injury in mice with fatty liver disease and its mechanism. Methods A total of 25 male C57BL/6J mice were fed with 60% high-fat diet for 16 weeks, and then they were ...
HUANG Xijian, ZHAO Jinxin, LUO Lijian, LIU Huan, CAI Jinzhen
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Studies on the inhibitory mechanism of Crocodile choline on cholangiocarcinoma cells and Chronic toxicity on rats [PDF]
目前,中医药中动物药对恶性肿瘤的作用受到人们越来越多的关注,由于其疗效显著、治疗后不易复发、毒副作用小等特点,在临床上得到广泛的应用。其中动物胆汁的抗肿瘤作用在国内外都受到了极大的关注。 本论文以体外培养的人胆管癌Mz-ChA-1细胞为对象,通过一系列的分离纯化手段从暹罗鳄胆汁中提取到获得具有抑制胆管癌细胞生长的活性物质鳄胆素,并进一步探讨其抑制胆管癌细胞生长的作用机理。应用普通光学及荧光显微镜观察鳄胆素对Mz-ChA-1细胞形态学的影响;PI单染检测细胞周期变化;AnnexinV-FITC ...
宋巍
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Research on the hunting right [PDF]
狩猎自人类的诞生以来,一直是人类生产活动的一种主要方式。到了现代社会,由于生产力的发展,狩猎由生产活动转变为一种商业和娱乐活动。而如何在狩猎活动与野生动物保护之间寻求平衡点成为理论界与实践界面临的一个难题,为此,各国都是努力建构各自的狩猎权法律制度,力求协调好这一矛盾。目前,我国在狩猎权方面的立法仍很不完善,问题较多,也影响到了我国狩猎活动的开展,因此,我国急需完善的狩猎权法律制度。 本论文包含前言,正文,结论三个部分,其中正文分为三章。 本文的第一章为“狩猎权概念之分析”。本章从狩猎权概念的定义 ...
覃明
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The negative regulatory effect of connexin 43 on myocardial injury in rats with common bile duct ligation and its mechanism [PDF]
Objective To investigate the role and molecular mechanism of connexin 43 (Cx43) in rats with myocardial injury induced by common bile duct ligation (CBDL).
WANG Xiaoyu, LYU Lin, YANG Han, ZHU Lin, DONG Shengnan, DONG He
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