Results 71 to 80 of about 29,509 (170)
A Clinical Observation of Concomitant Therapy of Erlotinib and Whole Brain Radiotherapy in Patients of NSCLC Combined with Brain Metastases [PDF]
, 2009 Background and objective Treatments to brain metastases in patients of NSCLC include operation, chemotherapy and radiotherapy, while the disease control rate of brain lesions is not so good, the media survival time is 4-6 months.
Jing ZHAO, Lihong ZHANG, Qiang FU
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Zhongguo shiyan zhenduanxue, 2017 目的探讨血清中miR-19b,miR-125b,miR-34a,miR-200b的表达与非小细胞肺癌发生发展的相关性,以及这4种microRNAs在化疗过程中表达水平的变化和对患者化疗的监测效果。方法采用实时荧光定量PCR（Real-time PCR）技术检测43例健康体检者和非小细胞肺癌患者血清中miR-19,miR-125b,miR-34a,miR-200b的表达水平,以及化疗过程中的表达变化,比较第二次、第六次化疗后microRNAs的表达差异。结果与健康对照组相比,非小细胞肺癌患者血清中miR ...
王丹丹, 刘牟林, 李士军
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The synthesis and investigation of Silica/Lipid related nanohybrid for anti-cancer drug delivery [PDF]
, 2015 化学治疗法是肿瘤学中最广泛应用的方法，但传统的化疗药给药方式存在靶向性低，毒副作用大，容易出现肿瘤耐药性等多重障碍，严重影响了癌症的治疗。现如今，随着纳米科技的发展，设计出一种纳米载药系统应用于化疗药物的传递，从而降低给药剂量、降低毒副作用、提高细胞吸收具有明显的临床意义。在诸多纳米粒材料的选择中，硅纳米粒由于其具有诸多良好的物理化学性质被广泛应用于药物传递及生物成像，然而普通二氧化硅纳米粒性质较为单一且载药量较小；介孔二氧化硅药物容易渗漏，靶向释放性能较差，这些都限制了二氧化硅纳米粒的进一步发展和应用。
刘泽华
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鲑鱼降钙素联合氯化锶对恶性肿瘤骨转移性骨痛及对血锶代谢影响的临床观察
Zhongguo shiyan zhenduanxue, 2016 目的观察降钙素联合氯化89鍶治疗恶性肿瘤骨转移痛的疗效,判断降钙素在治疗中的作用。方法 73名恶性肿瘤骨转移病例分为,联合组29例患者,用氯化89鍶（3-4mci iv）+降钙素（100IU喷鼻1次/天）;氯化89鍶治疗组25例患者,用氯化89鍶（3-4mci iv）和对照组19例患者,不同意锶治疗的肿瘤骨转移病人（其它方法治疗骨痛）,观察镇痛总有效率并以火焰原子吸收法测定全血鍶含量,随诊12个月,2例死亡退出观察。结果联合治疗组疗效高峰出现在第一个月,总有效率96.4%（27/28 ...
张云平, 李仰康, 刘阳晨
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Zhongguo shiyan zhenduanxue, 2009 目的探讨乳腺癌新辅助化疗对血清肝细胞生长因子水平的影响及相关临床意义。方法应用酶链免疫吸附法（ELISA）检测100例可手术乳腺癌患者新辅助化疗前及术后的血清肝细胞因子水平,并评估其水平与乳腺癌新辅助化疗疗效的关系。结果血清肝细胞生长因子水平与乳腺癌的分期密切相关（P=0.018）;血清肝细胞生长因子水平在治疗前后的变化与新辅助化疗效果密切相关。结论血清肝细胞生长因子可能在乳腺癌的发生发展中起重要作用,可能是预测化疗疗效的独立指标。
王承正, 毛书明, 崔树德
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Immediate Versus Delayed Topotecan after First-line Therapy in Small Cell Lung Cancer [PDF]
, 2010 Background and objective How to prolong progression free survival (PFS) and overall survival (OS) of patients with small cell lung cancer (SCLC) has been one of the hottest issues. We retrospectively reviewed our data to compare the survival of immediate
Cong XUE +7 more
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Survival Analysis of 1,742 Patients with Stage IV Non-small Cell Lung Cancer [PDF]
, 2011 Background and objective At present non-small cell lung cancer (NSCLC) is still the leading cause of death induced by cancer. The aim of this study is to investigate the prognostic factors of advanced NSCLC.
Baohui HAN, Hong PENG, Meili MA
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The Analysis of Erlotinib on Brain Metastases in Patients with Non-small-cell Lung Cancer [PDF]
, 2009 Background and objective Brain metastases are common in non-small-cell lung cancer (NSCLC) and the prognosis is poor. Erlotinib is a specific inhibitor of the epidermal growth factor receptor-associated tyrosine kinase (EGFRTKI), which has been gradually
Baohui HAN, Hao BAI
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Zhongshan Daxue xuebao. Yixue kexue ban, 2011 【目的】 探讨嗅神经母细胞瘤的临床特征治疗模式及预后 【方法】 回顾分析1986-2007年收治的44例嗅神经母细胞瘤,其中A/B期19例,C/D期25例全组单纯手术9例,单纯放疗6例,单纯化疗3例,手术+放疗10例,化疗+手术1例,化放综合治疗15例(化疗+放疗11例,化疗+放疗+化疗3例,放疗+化疗1例)【结果】 A/B期患者接受手术与非手术治疗相比,5年局部控制率分别为62.5%和50.0%(P = 0.06),5年总生存率分别为51.9%和16.7%(P = 0.03 ...
doaj
The Role of Postoperative Radiotherapy on Stage N2 Non-small Cell Lung Cancer [PDF]
, 2009 Background and objective The clinical value of postoperative radiotherapy (PORT) in stage N2 nonsmall-cell lung cancer (NSCLC) is controversy. The aim of this study is to analyze the efficacy of PORT in subgroup of stage N2 NSCLC, which can help ...
Changli WANG +7 more
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