应用RT-PCR和荧光原位杂交监测急性早幼粒细胞白血病微小残留白血病
Zhongguo shiyan zhenduanxue, 2012 目的应用RT-PCR和荧光原位杂交技术（FISH）检测急性早幼粒细胞白血病（APL）患者体内PML-RARα融合基因的表达,监测患者体内微小残留白血病的情况。方法采用全反式维甲酸（ATRA）和三氧化二砷（As2O3）联合治疗APL,运用RT-PCR和FISH技术检测和分析APL患者体内诱导缓解后及巩固维持治疗后PML-RARα融合基因。结果 46例APL患者PML-RARα融合基因均为阳性,其中34例患者在诱导化疗结束达完全缓解后检测,25例（73.5%）患者基因检测呈阴性,9例（26.5%）患者RT ...
张济 +4 more
doaj
细胞色素C及相关细胞凋亡蛋白、基因在原发性肝癌组织表达的临床意义
Zhongguo shiyan zhenduanxue, 2011 目的观察外源性凋亡通路中Caspase8和Bid及内源性凋亡通路中Bcl-2、Bax、细胞色素C（Cyt-C）和Cas-pase9在50例原发性肝细胞癌（肝癌组）及30例正常肝组织（对照组）中的表达,并分析其与病理分期、肿瘤分化程度和淋巴结转移的关系。方法应用免疫组织化学方法检测Bax表达,应用核酸原位分子杂交方法检测Caspase8、Bid、Bcl-2、Cyt-C和Caspase9表达。结果 Caspase8表达强度与对照组比较呈升高趋势（P0.05）。Bid阳性表达率与对照组比较呈下降趋势（P0 ...
陈昊 +5 more
doaj
[Spatial omics in pulmonary fibrosis: advancing mechanistic insights and therapeutic strategies]. [PDF]
Zhejiang Da Xue Xue Bao Yi Xue BanPeng Y, Xie Y, Yang F, Qiao X, Tian Y.
europepmc +1 more source
[Clinical and genetic analysis of two families with combined defect in antithrombin and protein C genes]. [PDF]
Zhonghua Xue Ye Xue Za ZhiGuo YL +6 more
europepmc +1 more source
[Design and synthesis of molecularly imprinted polymers and their applications in medical diagnosis and biocatalysis]. [PDF]
Se PuSong Q, Li X, Lyu Y.
europepmc +1 more source
[Oral homeostasis imbalance under hypoxia]. [PDF]
Hua Xi Kou Qiang Yi Xue Za ZhiXu Y, Wang S, Zhou J.
europepmc +1 more source
[Drug repositioning prediction based on dynamic feature learning on heterogeneous graphs]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoZhu H, Guo Y, Xin X, Li C, Zhou D.
europepmc +1 more source
[Research progress in the application of molecular imprinting technology in catalysis]. [PDF]
Se PuYe WM +5 more
europepmc +1 more source
[Preparation of superhydrophilic imprinted resin-graphene aerogel composite and its precise recognition of tumor biomarker in urine]. [PDF]
Se PuWang M, Tian T, Bai L, Han D, Yan H.
europepmc +1 more source