Results 111 to 120 of about 842,042 (203)
1、Sigma受体配体及其偶联药物的合成与生物学活性初步研究 2、多花黄精寡糖的分离纯化及四糖结构研究
, 2016 本文由（1）Sigma (σ) 受体配体及其偶联药物的合成与生物学活性初步研究和(2)多花黄精寡糖的分离纯化及四糖结构研究两部分组成σ受体作为重要的药物作用靶点，其信号转导机制研究表明，σ受体在肿瘤重大疾病中具有重要作用，其药理配体在肿瘤治疗中的作用一直是基础研究和国际制药领域的热点。因此，本论文首先在课题组前期新发展起来的高亲和力的羰基1,4’-联哌啶醇类σ受体配体基础上, 发展具有普适性的高效和高选择性的合成策略和抗癌活性研究。以1,2,5,6-四氢吡啶为起始原料，通过保护、环氧化 ...
潘伟
core
Rare Metals, Volume 45, Issue 10, October 2026.ABSTRACT High‐yield photocatalytic H2O2 production in sacrificial agent‐free pure water constitutes a critical bottleneck requiring urgent advances in energy catalysis. Although ZnIn2S4 (ZIS) exhibits favourable visible light absorption, it is plagued by severe bulk charge carrier recombination and scarce accessible surface‐active sites.
Sheng Liu +7 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2019 目前已有研究证实限制性输液的优势,随着术后快速康复的发展,限制性输液不但不会增加术中后出现肝肾功能异常风险,而且有利于患者术后的恢复[1,2]。在麻醉过程中,患者的交感神经受到抑制,血管平滑肌松弛,血管扩张,液体存在相对不足。为维持循环稳定,使循环系统维持在稳定的生理状态,α受体激动剂成为良好的选择。去甲肾上腺素激动α受体,对β1受体激动作用很弱,对β2受体几乎无作用 ...
马奔卉, 李艳辉, 王丹, 麻海春
doaj
World Affairs, Volume 189, Issue 4, Winter 2026.ABSTRACT The move from unipolarity to a fluid and contested multipolar world order has significantly changed the way African nations form national security policy due to changes in the nature of the strategic environment of those states. Much of the literature has focused on how the actions of major world powers ‐ the United States, China and Russia ...
Chick Edmond +2 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2001 【目的】探讨供受体体质量不相近时供心血管通路比例对心脏移植模型成功率的影响。【方法】建立大鼠颈部心 脏移植模型, 按供受体体质量比例和移植心流出道与流入道内径比例分组手术, Logistic 回归分析结果。【结果】供体体质量 小、供受体体质量相差>20%时, 调整血管通路比例对模型成功率有明显影响。【结论】对小体质量个体供心而言调整流出道 与流入道内径比可增加模型成功率、减少并发症。
陈振光
doaj
[Research on immunological function of platelet receptor FcγRⅡA]. [PDF]
Zhonghua Xue Ye Xue Za Zhi, 2023 Zhang Z, Zhou XH, Cheng ZP, Hu Y.
europepmc +1 more source
Asian Politics &Policy, Volume 18, Issue 4, October 2026.ABSTRACT Indonesia's responses to Illegal, Unreported, and Unregulated Fishing (IUUF) shifted from assertive measures such as publicly bombing and sinking illegal ships to legal, educational, and cooperative measures. The changes in policies undertaken are puzzling, given that Indonesian policymakers' perception of IUUF has remained the same between ...
Bama Andika Putra, Abdul Razaq Cangara
wiley +1 more source
子宫内膜分泌不良不孕妇女内膜胞浆女性#br# 激素受体和相关血清激素水平关系探讨
Zhongshan Daxue xuebao. Yixue kexue ban, 1989 本文对内膜分泌不良妇女子宫内膜胞浆雌、孕激素受体含量变化及血清雌二醇、孕酮、促卵泡成热激素及垂体泌乳素水平进行了分析讨沦,了解子宫内膜发育与雌、孕激素受体及血清有关激素之间的关系。结果表明,内膜分泌不良组与对照组比较,雌激素受体含量明显降低 ...
doaj
Zhongguo shiyan zhenduanxue, 1998 探讨反义ＴＧＦ－βＲＮＡ调节其受体表达及防治肝纤维化的机制。方法本实验将反义ＴＧＦ－β１基因导入ＣＣｌ４诱导的大鼠纤维化肝脏，用原位杂交方法观察ＴＧＦ－β受体的表达。结果发现纤维化肝脏ＴＧＦ－βⅠ型受体主要分布于汇管区周围及纤维间隔内和散在分布于肝实质内，Ⅱ型受体则主要分布于肝脏实质肝细胞和纤维间隔及汇管区，且均较正常组明显。经转基因处理后大鼠纤维化肝脏Ⅰ、Ⅱ型受体的分布未发生改变，但阳性反应明显减弱，阳性细胞数量明显降低，且肝脏纤维间隔也明显减少，其中Ⅱ型受体阳性的肝细胞数量减少极为明显 ...
梁志清, 何振平
doaj
Toward a Concept of ASEAN Autonomy: Actors, Entities, and Regional Space
Asian Politics &Policy, Volume 18, Issue 4, October 2026.ABSTRACT Widely discussed across disciplines, autonomy is often used in ASEAN studies to describe what actors associated with ASEAN seek. Yet its meaning remains underspecified and differs from dominant approaches of international organization autonomy.
Riko Watanabe
wiley +1 more source