前列腺素E2体外主要通过活化受体EP4促进人CD34+ 细胞增殖
摘 要: 【目的】 明确介导前列腺素E2(PGE2)促进人CD34+细胞增殖的具体受体亚型。【方法】 收集2013年6月至2014年10月期间18例健康志愿者经G-CSF动员的外周血,采用免疫磁珠法分选人CD34+细胞,并用流式细胞术鉴定其纯度;用qRT-PCR检测经PGE2作用后的人CD34+细胞中PGE2四个亚受体(EP1 ~ EP4)mRNA表达情况;根据处理方法不同,将人CD34+细胞分为对照组、前列腺素E2(PGE2)组、前列腺素E2受体EP2激动剂(EP2A)组、EP2A ...
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本发明公开了一种基于光子晶体表面态的二维光子晶体分束器,包括一个四方晶格光子晶体W1波导,在光子晶体W1波导的出口端两侧的光子晶体表面各含有一行半径不同的缺陷层四方晶格光子晶体介质柱,并在光子晶体W1波导出口端附近有一缺陷腔;在该缺陷腔的外侧含有一列起反射作用的四方晶格光子晶体介质柱,该四方晶格光子晶体介质柱与该缺陷腔一起调节光场分布。利用本发明,解决了传统分束器面积较大 ...
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Yang M, Li Y, Yang Q, Su B.
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DU O, Duan S, Tang L, DU J.
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[Orexin-A promotes motor function recovery of rats with spinal cord injury by regulating ionotropic glutamate receptors]. [PDF]
He G +9 more
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[Sulfasalazine relieves cholestatic liver injury by activating peroxisome proliferator-activated receptor-α]. [PDF]
Xu J +10 more
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Xiang H +6 more
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