Identification of Tiletamine, Zolazepam and Their Metabolites in Drug Facilitated Sexual Assault by GC-QTOF-MS#br# [PDF]
, 2019 Objective To identify tiletamine, zolazepam and their metabolites in samples from drug facilitated sexual assault by gas chromatography-quadrupole time of flight mass spectrometry （GC-QTOF-MS）.
HE Si-yang, GONG Fei-jun, LIAN Ru,et al.
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Relationship between Blood Acetaldehyde Concentration and Psychomotor Function of Individuals with Different ALDH2 Genotypes after Alcohol Consumption [PDF]
, 2019 Objective To explore the change rules of blood ethanol and blood acetaldehyde concentration, the impairment of psychomotor functions of different acetaldehyde dehydrogenase （ALDH） 2 genotype individuals after alcohol consumption and the relationship ...
YE Yi, CHEN Fan, WU Hao, et al.
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Effect of dexmedetomidine on postoperative sleep quality and complications in women undergoing elective cesarean delivery [PDF]
Objective To evaluate the effect of dexmedetomidine on postoperative sleep quality and complications in women undergoing elective cesarean delivery.
YOU Yiying, ZHONG Weilong, WANG Yanling, LI Liping
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Zhongguo shiyan zhenduanxue, 2020 目的观察布托啡诺联合右美托咪定超前镇痛对于麻醉苏醒期躁动的影响。方法择期在全麻下行开腹手术的患者80例,采用随机数字表法将其分为两组,每组40例。右美托咪定组(D组)患者在术前给予布托啡诺2mg并开始以0.5μg/kg静脉输注右美托咪定至手术开始时。生理盐水组(C组)在同一时间点给予生理盐水2mg并且以同等剂量开始输注右美托咪定至手术开始时。记录两组患者的一般情况,术中特定时间点的血压及心率总体波动幅度变化。患者在PACU期间的拔管时间、躁动分级评分及Riker镇静躁动评分。术后患者的视觉模拟疼痛评分 ...
高蓝天, 李春萍
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Zhongguo shiyan zhenduanxue, 2021 近年来,随着治疗技术的不断提升,减重代谢手术已成为治疗病态肥胖的首选治疗方法,然而,肥胖患者仍会伴随很多相关并发症,如心脑血管疾病、呼吸系统疾病、关节肌肉疾病以及代谢相关综合征,上述并发症在围术期给麻醉医生带来极大的挑战,并严重影响着手术结果。麻醉用药右美托咪定是一种新型a2肾上腺素受体激动剂,其独特药理和代谢的特点,使得右美托咪定在临床麻醉中的应用更加广泛,但目前其在肥胖患者减重手术中的相关研究鲜少。本文将围绕右美托咪定在病态肥胖患者减重代谢手术中的应用进展作一概述。
俞贝贝 +4 more
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Esketamine combined with dexmedetomidine and lidocaine induced inbition of tracheal intubation response [PDF]
Objective To investigate the median effective dose （ED50） of esketamine for inhibiting tracheal intubation response during the induction of dexmedetomidine combined with lidocaine under opioid-free anesthesia （OFA）.
DENG Dongxiang, WU Duozhi
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七氟烷、丙泊酚与老年肺癌手术患者术后早期认知功能障碍关系的Meta分析 [PDF]
, 2019 目的:系统评价丙泊酚与七氟烷对老年肺癌患者术后早期认知功能的影响。方法:计算机检索Cochrane Library、Pubmed、Web of Science、中国知网、维普智立方、万方数据知识服务平台中关于丙泊酚、七氟...湖北省自然科学基金项目(2012FFC004);; 湖北省教育厅青年项目 ...
侯丽娟 +4 more
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Clinical research of Dexmedetomidine in epileptic resection of functional brain areas [PDF]
, 2015 第一部分右美托咪定和丙泊酚对癫痫病灶切除术中皮层脑电图的影响 目的观察不同剂量右美托咪定和丙泊酚对癫痫病灶切除术中皮层脑电图（electrocorticography,ECoG）的影响。 方法ASA级Ⅰ～Ⅱ择期行癫痫病灶切除术患者100例，随机分为五组（每组20例），丙泊酚1.5ug/ml组（C1组）、5.0ug/ml组（C2组）、右美托咪定0.25ug•kg-1•h-1组（D1组）、0.5ug•kg-1•h-1组（D2组）、1.0ug•kg ...
王玉玺
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Research progress in the central nervous system mechanism of dexmedetomidine [PDF]
Dexmedetomidine, which is an α2 adrenergic receptor agonist with sedative, analgesic, anxiolytic and anti-sympathetic effects, has become a widely used drug in clinical anesthesia and intensive care unit (ICU). Compared with other drugs in the department
JIANG Linhao +3 more
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右美托咪定对重症脑卒中患者镇静效果及对血清S100β蛋白的影响
Zhongguo shiyan zhenduanxue, 2020 神经外科重症患者的麻醉和镇痛是临床上普遍重视的一个研究领域[1,2]。以往,咪达唑仑(Midazolam)是神经外科重症患者应用最广的镇静药物。近年来,右美托咪定(Dexmedetomidine,Dex)也被应用于颅内血肿、颅脑损伤、脑肿瘤[3-5]和脑卒中患者[6,7]行全身麻醉气管插管和机械通气时的镇静过程。新近研究发现:右美托咪定在脑卒中动物模型镇静的神经保护机理研究中,被证实与影响血清S100β蛋白相关[8]。我们观察了右美托咪定对重症脑卒中患者的镇静效果及镇静过程中血清S100β蛋白的变化 ...
刘晓, 李小静
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