Prevention of dexmedetomidine on postoperative delirium and early postoperative cognitive dysfunction in elderly patients undergoing hepatic lobectomy. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2022 Tang Y +5 more
europepmc +1 more source
Zhongguo shiyan zhenduanxue, 2017 苏醒期躁动（EA）为患者在全麻苏醒期意识障碍的一种表现,可出现粗暴的动作和自身的意外伤害,若处理不当,可造成严重的后果,甚至威胁生命安全。有研究[1]表明右美托咪定可以有效的预防苏醒期躁动,但对于剂量与给药方式仍未达成共识。本研究旨在观察右美托咪定的不同给药方案是否能够有效的预防神经外科手术麻醉苏醒期躁动。
刘娜 +4 more
doaj
Safety and efficacy of dexmedetomidine hydrochloride combined with midazolam in fiberoptic bronchoscopy in children: a prospective randomized controlled study. [PDF]
Zhongguo Dang Dai Er Ke Za Zhi, 2021 Zhang J +6 more
europepmc +1 more source
Zhongguo shiyan zhenduanxue, 2013 目的观察不同剂量右美托咪定复合靶控瑞芬太尼用于清醒插管的效果。方法择期全麻手术患者40例,按照美国麻醉医师协会(ASA)分级为Ⅰ-Ⅱ级,采用随机数字表法,将患者分为右美托咪定0.25μg.kg-1.h-1(D1组)、0.5μg.kg-1.h-1(D2组)、1.0μg.kg-1.h-1(D3组)和对照组(C组)每组10例。所有患者入室后均给予1﹪丁卡因行口腔,舌根表面麻醉,D1、D2和D3组分别给予右美托咪定1.0μg.kg-1.h-1恒速泵入10min,随后分别以0.25μg.kg-1.h-1、0 ...
王东昕, 金洪永, 姜新, 刘卓
doaj
[Protective effect of ulinastatin combined with dexmedetomidine against hepatic ischemia-reperfusion injury in laparoscopic hepatectomy for liver cancer and cirrhosis: a randomized controlled trial]. [PDF]
Nan Fang Yi Ke Da Xue Xue Bao, 2022 Ou Y, Liu G, Yin F, Yang Y, Zhang F.
europepmc +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2012 【目的】 在腹部手术中,以丙泊酚?瑞芬太尼 TCI 为基础的全凭静脉麻醉,全程复合使用右旋美托咪定,探讨其对丙泊酚用量?术后拔管时间?睁眼时间和复苏期血流动力学变化等指标的影响?【方法】入选患者随机分成实验组1(DEX1)?实验组2(DEX2)?对照组(Control)3组?DEX1组患者于15 min内输注0.5 μg/kg右旋美托咪定,随即以0.25 μg· kg-1· h-1输注右旋美托咪定至拔管;DEX2患者于15 min内输注0.5 μg/kg右旋美托咪定,随即以0.5 μg· kg-1· h-
doaj
氟比洛芬酯复合右美托咪定对瑞芬太尼诱发患者术后痛觉过敏的影响
Zhongguo shiyan zhenduanxue, 2016 瑞芬太尼因具有药效强、可控性强、起效迅速、无蓄积等特点,广泛应用于临床[1]。但瑞芬太尼是一种超短效的阿片受体激动剂,长时间或大剂量应用易诱发痛觉过敏[2-4]。研究表明,单独应用氟比洛芬酯和右美托咪定均可预防瑞芬太尼诱发的术后痛觉过敏[5-6]。而单独应用氟比洛芬酯易引起恶心呕吐、皮肤瘙痒等不良反应[7 ...
王晓燕 +4 more
doaj
[Effect of Ropivacaine Combined with Dexmedetomidine for Serratus Anterior Plane Block Plus Patient-Controlled Intravenous Analgesia on Postoperative Recovery Quality of Patients Undergoing Thoracoscopic Radical Resection of Lung Cancer]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue Ban, 2023 Zhang JR, Jian JJ, Cao LL, Dong N.
europepmc +1 more source
[Dexmedetomidine can not reduce the incidence of acute and chronic kidney disease after laparoscopic radical nephrectomy: a propensity score matching-based analysis]. [PDF]
Nan Fang Yi Ke Da Xue Xue Bao, 2023 Su Y +6 more
europepmc +1 more source