Association of extravascular lung water with clinical outcomes in stages 4 and 5 chronic kidney diseases: a prospective cohort study [PDF]
, 2023 Objective To evaluate the impact of extravascular lung water volume on cardiovascular events， renal replacement therapy and mortality in pre-dialysis patients with stages 4 and 5 chronic kidney diseases.
Wang Jiawei, Luo Qiong, Lu Laishun, Hong Chunyan, Tang Xiaoling
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中青年超重和肥胖与高血压及高同型半胱胺酸血症的相关性 [PDF]
Objective: To investigate the correlation between high blood pressure, high HCY and overweight as well as obesity in young and middle-aged adults by observing BMI and high HCY levels.
Yang, Wen-dong
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Analysis of Irrational Drug Use and Intervention Countermeasures of Pediatric Prescriptions in Western Medicine [PDF]
, 2017 目的 分析西药房中儿科处方的不合理用药情况及干预对策。方法 纳入的研究对象为2015年3月—2016年3月我院西药房中儿科的80例处方,开展门诊处方调剂前干预和调剂前未干预两种方式的比较。结果 调剂前干预后较调剂前未干预用药不合理情况更低（P〈0.05）。结论 对西药房儿科处方开展合理的用药干预,可明显降低处方的用药不合理情况,值得临床深究。Objective To analyze the irrational drug use of pediatric prescriptions in the ...
许冰茹
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Changes of serum uric acid, bilirubin and homocysteine levels in patients with early Parkinson’s disease [PDF]
目的 观察早期帕金森病并伴有轻度认知功能障碍（PD-MCI）患者血清间接胆红素（IBIL）、尿酸（UA）、同型半胱氨酸（Hcy）及尿酸/同型半胱氨酸比值（UA/Hcy）的变化，探讨其与PD-MCI的关系。 方法 收集158例早期未经药物治疗的帕金森病（PD）患者的人口学及临床资料，应用Hoehn & Yahr分级评估PD严重程度，MDS-UPDRS III评估运动障碍，蒙特利尔认知评估量表（MoCA）评估全面认知功能状态。102例年龄匹配的健康体检者作为对照组。检测各组血清IBIL ...
Li, Zhen-guang +2 more
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Correlation between serum homocysteine level and clinicopathological factors of IgA nephropathy [PDF]
ObjectiveTo investigate the correlation between serum homocysteine （Hcy） and clinicopathologic factors of immunoglobulin A nephropathy （IgAN）.MethodsA total of 349 patients with IgAN diagnosed by renal biopsy in the Nephrology Department of Longhua ...
Cai Xiao-fan +5 more
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Structural and Functional Characterization of the Signaling Molecule Autoinducer-2 Synthesis Enzyme S-Ribosylhomocysteinase in Limosilactobacillus fermentum [PDF]
S-ribosylhomocysteinase (also referred to as LuxS protein) is an important enzyme involved in the biosynthesis of autoinducer-2 (AI-2) as a signaling molecule.
WEI Guangqiang, WANG Teng, XU Ziqi, WANG Yuzhu, ZHANG Wenbin, LI Xinglun, HUANG Aixiang
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同型半胱氨酸对人脐静脉内皮细胞线粒体膜电位的影响 [PDF]
Objective: To observe the changes of endothelial mitochondrial membrane potential（MMP）by building Hcy-induced endothelial impairment model in cultured human umbilical vein endothelial cells and to analyze the mechanism of Hcy-induced apoptosis.Methods: (
Li, Zhan-quan, Shi, Yun-qi, Wang, Hao
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Comparative Genomic Analysis of Functional Genomics of Lactiplantibacillus plantarum ST [PDF]
, 2023 In this study, the functional genomic characteristics of Lactiplantibilus plantarum ST were analyzed. Comparative genomic analysis was performed on the whole genome sequences of L. plantarum ST and the type strain L.
YANG Shujuan, ZHOU Jinping, LI Haiyan, CAO Zhenhui, SUN Zhihong, LIN Qiuye
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Triglyceride-glucose index and homocysteine in association with the risk of stroke in middle-aged and elderly diabetic populations [PDF]
ObjectiveTo investigate the triglyceride-glucose (TyG) index and the level of serum homocysteine (Hcy) in association with the incidence of stroke in type 2 diabetes mellitus (T2DM) patients.MethodsBased on the chronic disease risk factor surveillance ...
GAO Jiaojiao +13 more
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NMR-based Metabonomics Study of Patients with Cerebral Infraction Complication in Type 2 Diabetes Mellitus [PDF]
, 2013 目的应用氢谱核磁共振代谢组学(1H-nMr)方法研究2型糖尿病(T2dM)合并脑梗死患者血清中小分子代谢物代谢轮廓的变化,探讨2型糖尿病合并脑梗死的可能发病机制。方法选择T2dM合并脑梗死患者19例、单纯T2dM患者25例及健康对照者29例,利用1H-nMr方法检测血清的代谢轮廓,通过偏最小二乘判别分析方法,鉴别各组别间血清小分子代谢物的区别。结果从血清偏最小二乘判别分析得分图中可以区分3组患者,与T2dM合并脑梗死有关的特征代谢物包括极低密度脂蛋白、低密度脂蛋白、葡萄糖、乳酸、丙酮酸、3-羟基丁酸、n-
杨香玖 +4 more
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