The Research on Lamina Cribrosa Stress, Deformation and Damage Under Intraocular Pressure
青光眼是世界上第一大不可逆性的致盲眼病。其病变与眼内压直接关联,但发病的确切机制尚不明确。目前已经证实青光眼患者存在筛板结构与形态的变化,筛板前后承受的眼内压与颅内压之间的跨筛板压力差增大,会导致青光眼视神经损害。自上世纪80年代确定了筛板作为青光眼视神经损害的原发部位后,筛板就成为研究青光眼视神经损害的热点。筛板是位于视乳头中的多孔板状结构,由十余层纤维薄板构成,周边与巩膜相连,力学上可以看成一个承受均匀分布的横向载荷的圆形板。以前的研究,都是基于经典Kirchhoff薄板理论建立的筛板力学模型 ...
田晗菁
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