Results 21 to 30 of about 5,005 (119)

RVP Fast与Seeplex PneumoBacter ACE Detection assay联合诊断呼吸道感染病原体

open access: yesZhongguo shiyan zhenduanxue, 2018
目的采用RVP Fast与Seeplex PneumoBacter ACE Detection assay两种方法,联合诊断呼吸道感染病原体。方法收集南京市呼吸道感染患者咽拭子标本67份,提取RNA及DNA,呼吸道病毒群快速检测(Respiratory Virus Panel Fast Array,RVP Fast)技术检测呼吸道病毒,Seeplex PneumoBacter ACE Detection assay检测呼吸道六重病原体。结果 67份标本中,呼吸道病毒阳性仅4例,主要为肠鼻病毒 ...
戴蕾, 郑齐锶, 东芳, 宁明哲
doaj  

Influenza virus infection of influenza-like illness at a sentinel hospital in Baoshan District of Shanghai from the monitoring year of 2015 to 2023 [PDF]

open access: yes
ObjectiveTo investigate the influenza virus infection status of influenza-like illness (ILI) at a sentinel hospital in Baoshan District of Shanghai, to explore the seasonal patterns of influenza, so as to provide a scientific basis for influenza ...
DOU Wenxia   +5 more
core   +1 more source

Establishment and Application of Monoclonal Antibody Bank against Hemagglutinin of 2009 H1N1pdm influenza virus [PDF]

open access: yes, 2012
H1N1流感病毒是影响人类健康的季节性流感病毒之一,在历史上曾发生过2次全球大流行,而2009年4月爆发的甲型H1N1流感(2009H1N1pdm)全球大流行,使得H1N1再次成为全球关注的焦点。疫情的控制需要高灵敏度、高特异性的诊断试剂,对于病毒的持续流行和变异需要及时掌握其变异规律,病毒变异持续产生的NA抑制剂的耐药株也提示有必要研究新型治疗性抗体药物。血凝素蛋白(HA)是流感病毒的重要膜蛋白,与病毒的抗原性和毒力密切相关,是研制特异性诊断试剂、疫苗和抗体治疗药物的重要靶标 ...
曾奋
core  

Characteristics and prognostic factors of chronic kidney disease patients with Pneumocystis jirovecii pneumonia [PDF]

open access: yes
ObjectiveTo explore the clinical and prognostic characteristics of chronic kidney disease (CKD) patients with Pneumocystis jirovecii pneumonia (PJP), thus facilitating the diagnosis and treatment of Pneumocystis jirovecii infections.MethodsWe ...
Ge Yi-fei   +6 more
core   +1 more source

9种呼吸道病原体IgM抗体联合检测的临床意义

open access: yesZhongguo shiyan zhenduanxue, 2016
目的了解9种非典型性病原体在呼吸道感染患者中感染率,探讨9种非典型性病原体IgM抗体联合检测在呼吸道感染中的临床意义。方法收集681例呼吸道感染患者(其中成人277例,儿童404例)血清,采用间接免疫荧光法(IFA)同时检测嗜肺军团菌(Lp)、肺炎支原体(Mp)、Q热立克次体(QFR)、肺炎衣原体(Cp)、腺病毒(ADV)、呼吸道合胞病毒(RSV)、甲型流感病毒(IAV)、乙型流感病毒(IBV)和副流感病毒(PIV)9种呼吸道病原体的IgM抗体。结果201、681例样本中共检测出IgM抗体阳性258例 ...
夏丽君, 巫雯嘉, 杨瑾
doaj  

Epidemiological characteristics of nasopharyngeal microbiota profiles in community children under 5 years in Haidong City, Qinghai Province [PDF]

open access: yes
ObjectiveTo describe the characteristics of the nasopharyngeal microbiota in children under 5 years of age in Haidong City, Qinghai Province and analyze its associated factors, so as to provide basic data for the evolution and development of ...
GUO Zizhe   +4 more
core   +1 more source

Effects of environmental pollutant exposure on the development of immune system in children [PDF]

open access: yes
Exposure to environmental pollutants can lead to the release of inflammatory factors and impaired immune function. Based on the e-waste recycling area, aiming to investigate the impact of pollutants on children's immune system development and associated ...
HUO Xia, XIE Bo, XU Xijin, ZENG Zhijun
core   +1 more source

肠-肺微生物群在免疫系统构建和调节中的重要作用 [PDF]

open access: yes
微生物与人体免疫系统的互动一直是生物医学研究的焦点。新一代测序发现不仅肠道,呼吸道也存在着微生物群,且肠-肺微生物群之间通过免疫细胞及其活性因子等形成了一个相互关联的网络。本综述旨在探讨肠道和肺部微生物群如何调节免疫应答,包括其在局部和全身免疫调节中的作用;同时,解析肠-肺轴之间的免疫联系 ...
张萌, 杨正飞
core   +1 more source

儿童肺炎支原体检测方法的研究进展

open access: yesZhongguo shiyan zhenduanxue, 2014
呼吸道感染是临床常见疾病,病死率高,WHO2008年公布低收入国家下呼吸道感染病死率达11.2%,排十大疾病死因第一位,中高收入国家,病死率为3.8%,位居十大疾病死因的第四位[1]。支原体肺炎是机体感染肺炎支原体而引起的肺部炎症,近年支原体肺炎的发病率出现逐年递增趋势[2]。肺炎支原体是常见的引起儿童呼吸道感染的病原体之一[3],导致儿童社区获得性肺炎(CAP)[4-5 ...
业晓青
doaj  

北京地区1459例成人呼吸道病原体IgM检测结果临床分析

open access: yesZhongguo shiyan zhenduanxue, 2019
目的探讨近年北京地区呼吸道感染患者常见病原体的感染分布情况。方法采用间接免疫荧光法对1459例呼吸道感染患者血清中11项病原体的IgM抗体进行检测分析。结果 1459例患者中共检出529例呼吸道病原体IgM抗体阳性,总阳性率为36.26%(529/1459)。其中阳性率最高的是流感病毒B型(INFB),阳性率为18.99%(277/1459);其次是流感病毒A型(INFA),阳性率为9.87%(144/1459)和肺炎支原体(MP),阳性率为9.80%(143/1459)。感染率与季节关系密切 ...
李晓晨, 赵志鹏, 赵秀英
doaj  

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