Results 11 to 20 of about 10,779 (208)
The efficacy and side effects of liposomal doxorubicin-based therapy and epirubicin-based therapy for breast cancer patients: a meta-analysis [PDF]
Objective To conduct a meta-analysis to explore the specific efficacy and side effects of liposomal doxorubicin (LD) and epirubicin (E)-based therapies in breast cancer patients.
DENG Lang +5 more
core +1 more source
Study on epidemiology and pathogenic spectrum of HFMD cases in Xiamen, 2013-2016 [PDF]
, 2016 手足口病由肠道病毒感染引起，是一种高发于0-5岁儿童的急性传染病，其在世界范围内出现多次大规模爆发流行，仅仅在中国大陆每年就有几百万例病例。手足口病的流行给公共卫生带来了威胁。目前仅有靶向EV71的手足口病单价疫苗上市，但由于肠道病毒病原的多样性，EV71单价疫苗可能无法有效控制疫情。因此对于手足口病病原谱的监测及主要病原分子进化的研究仍然十分重要。为此，本研究在前期建立的肠道病毒诊断分型方法的基础上，进一步完善检测体系，对厦门地区手足口病肠道病毒病原谱进行了全面的监测 ...
陈梦媛
core
地夫可特治疗杜氏肌营养不良有效性及安全性研究进展 [PDF]
地夫可特作为一种糖皮质激素类药物，有利于改善杜氏肌营养不良(Duchenne muscular dystrophy, DMD)患者运动功能和肌力、延迟患者丧失自主活动时间，改善肺功能，降低脊柱侧凸风险，延缓心肌病进展及提高生存率。2017年2月，美国食品药品监督管理局批准地夫可特用于治疗DMD。2024年5月，地夫可特以“临时进口”途径进入北京协和医院定点使用。本文从作用机制、药动学、临床疗效及不良反应等方面对其进行介绍，以期为地夫可特在临床中合理 ...
乔露瑶 +7 more
core +1 more source
Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Plant phenology is crucial for understanding plant growth and climate feedback. It affects canopy structure, surface albedo, and carbon and water fluxes. While the influence of environmental factors on phenology is well‐documented, the role of plant intrinsic factors ...
Yunpeng Luo +8 more
wiley +1 more source
Progress of Nimotuzumab Application in Nasopharyngeal Carcinoma [PDF]
Compared with the global average, the incidence rate of nasopharyngeal carcinoma (NPC) in China is higher, particularly in the southern regions where the mortality rate has remained persistently high.
Biaoxue RONG +6 more
core +1 more source
Evaluating the empirical basis for threat attribution in the IUCN Red List
Conservation Biology, EarlyView.Abstract Understanding the impacts of different threats on species is key to successful conservation interventions and policies. The International Union for Conservation of Nature (IUCN) assesses threats to species, and the organization's Red List of Threatened Species is a key conservation tool.
Ena Humphries +5 more
wiley +1 more source
Effect of intraoperative use of low-dose dexmedetomidine on the prognosis of patients undergoing breast cancer surgery [PDF]
, 2023 Objective·To investigate the influence of intraoperative dexmedetomidine infusion on the recurrence-free survival (RFS) and overall survival (OS) rate of patients undergoing breast cancer surgery.Methods·A retrospective analysis was performed on patients
CHU Xiaoying +3 more
core +1 more source
Jianzhu Gangjiegou Jinzhan, 2020 回顾总结了近年来高温下梁柱端板式连接节点力学性能相关的研究成果。针对三类常用的端板连接形式:外伸式端板、齐平式端板以及内缩式端板连接进行了细致讨论。同时,从试验研究、有限元分析以及组件法的高温运用等方面着手归纳了相应研究成果。首先,对近年来为数不多的端板式节点高温试验进行了回顾,包括针对孤立节点的高温试验以及针对子结构的高温试验。随后,对有限元方法和推广应用的组件法这两种理论研究方法进行了详细的归纳总结,细致讨论了各组件模型实际运用中的优势以及存在的不足。最后,根据已有的研究成果 ...
李炎地, 赵金城
doaj
Using incentive payments to promote human–carnivore coexistence
Conservation Biology, EarlyView.Abstract For many large carnivores, minimizing the financial burden they impose on local people is critical to their conservation. Incentive‐based programs that provide people with financial benefits for taking pro‐conservation actions or achieving conservation goals are a promising tool for promoting human–carnivore coexistence. Although the number of
Adam Pekor +9 more
wiley +1 more source