Results 101 to 110 of about 1,133,766 (142)

[State Changes and Stability Grading of Driver Genes in Non-small Cell Lung Cancer Based on Repeated NGS Testing]. [PDF]

Zhongguo Fei Ai Za Zhi
Zhao D, Xu F, Zhang L, Zhang N, Liu Z, Li K, Zhang C, Zhou L, Dong Y, Mu J, Che N.   +10 more
europepmc   +1 more source

小鼠肝脏特异性表达载体ALB-ATP7B的构建

Zhongshan Daxue xuebao. Yixue kexue ban, 2004
［目的 l 构建人肝豆状核变性病ATP7B基因野生型及常见突变型的小鼠肝脏特异性表达载体 ALB-ATP7B, 为制备转基因小鼠及相关基因治疗作准备。【方法】定点突变法获取人群中常见的Arg778Leu及 Hisl069Gln两种ATP7B基因突变体，定向克隆将小鼠白蛋白启动子ALB序列及野生和突变的ATP7B基因亚克 隆至真核表达载体kbpala上， 得到可在小鼠肝脏特异性表达的人ATP7B基因正常及突变型真核表达载体 ALB-ATP7B。【结果】经测序及酶切鉴定证实， 真核表达载体ALB ...
doaj  

[Somatic and immune profiling of chemotherapy-associated aplastic anemia: a comparison with primary aplastic anemia and cancer without aplastic anemia]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Zhang YM, Zhou YX, Zhuang QL, Han B.
europepmc   +1 more source

单纯疱疹病毒胸苷激酶与绿色荧光蛋白基因 真核共表达质粒的构建

Zhongshan Daxue xuebao. Yixue kexue ban, 2009
【目的】 构建含有人巨细胞病毒(CMV)调控表达的单纯疱疹病毒胸苷激酶(HSV-tk)与增强型绿色荧光蛋白(EGFP)基因真核表达质粒pCMV-TK-IRES-EGFP。【方法】 设计HSV-tk cDNA的特异引物,PCR扩增获得HSV-tk基因序列, 将PCR产物进行T载体克隆获得重组质粒pMD18T-TK,测序分析选定序列正确的克隆提取质粒,用限制性内切酶SalⅠ和BamHⅠ分别酶切pMD18T-TK和pCMV-IRES-EGFP质粒,将HSV-tk基因定向亚克隆至pCMV-IRES-EGFP载体,
doaj  

[Everolimus inhibits malignant phenotype of erdafitinib-resistant bladder cancer cells through the p70S6K/PI3K/MAPK signaling pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Wu H, Jiang Y, Zhang X, Wang S.
europepmc   +1 more source

[Phosphatidylinositol glycan anchor biosynthesis class T promotes malignant phenotype of colon cancer through the NF-κB signaling pathway]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Li B, Wang B, Mei X, Tian Y, Han L, Zhang J.   +5 more
europepmc   +1 more source

[Effects and mechanisms of broccoli-derived extracellular vesicles on wound healing of full-thickness skin defects in diabetic mice]. [PDF]

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi
Shen Q, Jian N, Zhang CP, Fu XB.
europepmc   +1 more source

[CRISPR-Cas9 activation screening identifies candidate chemokine regulators of ter-tiary lymphoid structure formation in bladder cancer]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Wang Y, Song H, DU Y, Xu T.
europepmc   +1 more source

[Methyltransferase-like protein 7B promotes glycolysis and malignant progression in papillary thyroid carcinoma cells via the USP28/HIF-1α axis]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Xu F, Xie Q.
europepmc   +1 more source

[Chronic lymphocytic leukemia presenting initially as purpura nephritis: a case report]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Tong MW, Nong WX, Zhang DQ, Pan X.
europepmc   +1 more source