Results 161 to 170 of about 31,733 (245)
供受体CYP3A5和MDR1基因多态性与肝移植术后患者他克莫司浓度/剂量比的关系
【目的】研究肝移植供受体CYP3A5和MDR1基因多态性对患者术后他克莫司浓度/剂量比的影响。【方法】选取我中心32例肝移植供受体,测定患者术后1、2、4、12周体质量、他克莫司用量及药谷浓度等指标,采用聚合酶链式反应-限制性内切片段长度多态性(PCR-RFLP)方法测定供受体基因分型,比较不同基因型对患者他克莫司浓度/剂量比值的影响。【结果】供体CYP3A5*1/*1和*1/*3型患者术后2、4、12周他克莫司浓度/剂量比明显低于*3/*3型患者(p0.05)。联合分析供受体CYP3A5基因型,术后2、
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[Prediction of hearing change in children with enlarged vestibular aqueduct with different genotypes by linear mixed-effects model]. [PDF]
Deng L +7 more
europepmc +1 more source
[The natural history of the relationship between <i>OTOF</i> mutation-related genotypes and audiological phenotypes]. [PDF]
Han L +9 more
europepmc +1 more source
[Clinical phenotypes and genotypes of congenital fibrinogen disorder: an analysis of 16 children]. [PDF]
Wang M +7 more
europepmc +1 more source

