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内质网应激与急性肺损伤恶化关联性的研究进展

Zhongshan Daxue xuebao. Yixue kexue ban
急性肺损伤（ALI）是一种严重威胁全球人类生命健康的疾病，其主要病理特征为肺泡上皮细胞和肺毛细血管内皮细胞的损伤，导致弥漫性肺间质水肿和肺泡水肿，通常伴有急性低氧性呼吸功能不全。内质网应激（ERS）在ALI的发生和发展过程中扮演着关键角色。它通过多种途径加剧急性肺损伤：在细胞凋亡方面，关键蛋白如GRP78、CHOP和caspase-12参与调控，促进肺血管内皮细胞和肺泡上皮细胞的凋亡，从而加重肺组织损伤；在ROS代谢方面，诱导活性氧（ROS）的大量释放，NADPH氧化酶等参与ROS的产生过程 ...
韩英, 胡丹丹
doaj  

[A method for emotion transition recognition using cross-modal feature fusion and global perception]. [PDF]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
Jie L, Zou Y, Li Z, Lyu B, Zheng W, Li M.   +5 more
europepmc   +1 more source

[The role of extracellular vesicles in early embryo development and their application in assisted reproductive technologies]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Wang H, Li X, Lan H, Tong X.
europepmc   +1 more source

[Characteristics of bronchoalveolar lavage fluid microbial distribution at different disease stages and its relationship with immune function in children with refractory <i>Mycoplasma pneumoniae</i> pneumonia]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Yao C, Zhang X, Xu R.
europepmc   +1 more source

[Feature distillation multiple instance learning method based on sequence reorganized Mamba]. [PDF]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
Zeng J, Luo W, Zhao J, Huang G, Zhao J, Mai Z, Yan W, Xiao Y, Qin C.   +8 more
europepmc   +1 more source

[Gandou Bushen decoction ameliorates ovarian injury in murine hepatolenticular degeneration via the AGE/RAGE/NF-κB signaling pathway]. [PDF]

Zhejiang Da Xue Xue Bao Yi Xue Ban
Jiang P, Wu L, Han H.
europepmc   +1 more source

[ERI3 expression is elevated in hepatocellular carcinoma and correlates with poor patient prognosis]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zhao X, Wang H, Song Y, Yuan S, Zhang Z, Zhou X, Li S, Li X, Li F.   +8 more
europepmc   +1 more source

[Overexpression of lncRNA SNHG12 promotes docetaxel resistance of prostate cancer cells by activating PI3K/AKT signaling <i>via</i> interacting with ELAVL1]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zhao C, Li W, Zheng B, Wang G, Xiao Z, Li Y.   +5 more
europepmc   +1 more source

[Endometrial cancer lesion region segmentation based on large kernel convolution and combined attention]. [PDF]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
Peng R, Zeng Q, He B, Liu J, Xiao Z.
europepmc   +1 more source

[Adolescent depressive disorder: prevalence, risk factors, current status of diagnosis and treatment, and challenges]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Cong EZ.
europepmc   +1 more source