Effects of Escherichia coli outer membrane vesicles on proliferation of breast cancer cells and tumor growth of tumor-bearing mice [PDF]
, 2023 Objective·To analyze the effect of Escherichia coli outer membrane vesicle (E.coli-OMV) on the proliferation of 4T1 breast cancer cells in vitro and the inhibition of tumor growth in BALB/c-4T1 tumor-bearing mice in vivo.Methods·OMVs were collected from ...
BAI Jin +5 more
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Distribution of blood culture pathogens and clinical characteristics in children with acute leukemia complicated with septic shock [PDF]
, 2022 Objective To explore the distribution of blood culture pathogens and clinical characteristics in children with acute leukemia complicated with septic shock.
Liu Tinghua, Lei Jiaying, Mai Yougang
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Zhongguo shiyan zhenduanxue, 2023 目的 探讨大肠埃希菌临床株QD24对黏菌素和碳青霉烯类耐药的机制。方法 通过二代Illumina和三代Nanopore测序技术平台获得大肠埃希菌QD24株的染色体和质粒序列，然后对其进行在线软件分析。液相接合试验、S1核酸酶切脉冲场凝胶电泳(S1-PFGE)和脉冲场凝胶电泳(PFGE))检测菌株携带的质粒。结果 测序分析显示大肠埃希菌QD24属于ST69型，携带了黏菌素耐药基因mcr-1.1和碳青霉烯类耐药基因blaNDM-13,且这两个基因分别位于IncHI2型质粒pQD24-1和IncB/O/K ...
王晓慧 +4 more
doaj
, 2019 细菌外膜囊泡(outer membrane vesicles, OMVs)是一种在不破坏细胞膜的情况下细菌正常分泌的球状小泡。近年来越来越多的研究表明外膜囊泡在病原微生物感染及致病过程中发挥着重要的作用,其作用机...国家自然基金(No.81473251; No.81301474; No.31741006);; 福建省中青年教师教育科研项目资助(No.JT180009);; 厦门大学校长基金(No ...
吴疆, 王岱, 程谦
core +3 more sources
Investigation and analysis of an outbreak of foodborne disease caused by Salmonella enteritidis in a district of Chongqing [PDF]
, 2023 ObjectiveTo provide the basis for dealing with similar incidents in the future， an outbreak of foodborne illness caused by the consumption of bread contaminated with Salmonella enteritidis was investigated.MethodsDescriptive epidemiological methods were ...
LUO Yu, XIAO Lun, XIONG Fei, YU Jin
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Food safety analysis and management of Shiga toxin-producing Escherichia coli in edible agricultural products and kitchen [PDF]
, 2020 The sources and transmission routes of Shiga toxin-producing Escherichia coli (STEC) in edible agricultural products are analyzed. And the relationship between STEC contamination and food safety in home kitchen is discussed.
Hongjun LI +6 more
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Study on multidrug resistance related genes of Salmonella isolated from food and clinical samples [PDF]
, 2023 ObjectiveTo investigate distribution of integron and extended-spectrum β-lactamase produced by Salmonella isolated from food and clinical samples， and explore the relationship between different drug resistance genes and multidrug resistance ...
GENG Yingzhi +3 more
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, 2018 抗生素发现\"黄金时代\"的结束以及日趋严重的抗生素耐药性问题给我们留下一个戏剧性的、缺乏新型药物来防治耐药病原体感染的难题。这使得从现有非抗生素药物中筛查抗菌活性药物成为一种新尝试。近期研究表明:美国食品药品监督管理局(FDA)批准的、本来用于治疗高血钙的药物硝酸镓具有良好的抗菌活性。不同于其他抗生素,镓的药理性质依靠化学拟态,它可以在目标酶分子中取代铁,从而干扰、扰乱细菌含铁蛋白的功能及细菌代谢,无论是在体外实验还是在体内实验中,镓对多种病原体,包括多重耐药病原体都表现出杀菌活性 ...
刘周 +6 more
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Research progress on microbial contamination and its prevention and control measures in ready-made beverages [PDF]
, 2023 Freshly squeezed fruit and vegetable juice， freshly ground coffee， new tea and other freshly made beverages are very popular among consumers. However， due to the loose quality control of raw materials and non-standard processing operation， the risk of ...
PENG Zixin +4 more
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Preparation and target protease identification of a cyanobacterial serine protease inhibitor, arthropin [PDF]
, 2023 Objective·To prepare a high-purity cyanobacterial serine protease inhibitor, screen its target proteases, and detect its inhibitory activity.Methods·A novel serine protease inhibitor from Arthrospira platensis was identified in the Expanded Human Oral ...
XU Jiawei, YANG Yufeng, ZHOU Aiwu
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