Results 41 to 50 of about 1,600,774 (153)

Aspirin delays preterm birth in pregnancies at high risk for preterm pre‐eclampsia: evidence from randomized clinical trial in Asia

open access: yesUltrasound in Obstetrics &Gynecology, Volume 66, Issue 1, Page 24-32, July 2025.
ABSTRACT Objectives To investigate the impact of aspirin administration on the incidence of preterm birth, according to the type of delivery and gestational age at preterm birth, and to examine the hypothesis that aspirin delays preterm delivery. Methods This was a secondary analysis of a multicenter stepped‐wedge cluster randomized trial of a first ...
H. H. Y. Leung   +29 more
wiley   +1 more source

血浆sCD40L、sICAM-1及血管内皮损伤相关细胞与子痫前期严重程度的相关性分析

open access: yesZhongguo shiyan zhenduanxue, 2017
目的探讨血浆白细胞分化抗原可溶性CD40配体(sCD40L)、可溶性细胞间粘附因子-1(sICAM-1)及血管内皮损伤相关细胞与子痫前期严重程度的相关性。方法选择年龄、BMI、检测孕周等临床一般资料相匹配的重度子痫前期、轻度子痫前期患者以及健康孕妇(对照组)各45例作为研究对象,采用ELISA法检测血浆sCD40L、sICAM-1水平,采用流式细胞仪检测内皮祖细胞(EPC)、血管生成性T细胞(Tang)含量,比较并分析其相关性。结果子痫前期组的血浆sICAM-1、sCD40L水平均明显高于对照组 ...
薛峰, 颜源, 何攀
doaj  

Assessment of risk for pre‐eclampsia at mid‐gestation to define subsequent care

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 6, Page 694-702, June 2025.
ABSTRACT Objective To stratify pregnancy care based on the estimated risk of pre‐eclampsia (PE) from screening at 19–24 weeks' gestation by combinations of maternal risk factors, estimated fetal weight (EFW), mean arterial pressure (MAP) and uterine artery pulsatility index (UtA‐PI).
S. Adjahou   +5 more
wiley   +1 more source

CRMP-1在早发型先兆子痫妇女胎盘中的表达水平及临床意义

open access: yesZhongguo shiyan zhenduanxue, 2018
目的检测早发型先兆子痫妇女胎盘中坍塌反应调节蛋白-1(CRMP-1)的表达,分析其与先兆子痫临床特点的关系。方法收集30例早发型先兆子痫、30例迟发型先兆子痫孕妇作为研究对象,另选取同时期因各种原因终止妊娠的健康孕妇60例,将其按照孕周进行匹配分别作为早发型先兆子痫的对照组A、迟发型先兆子痫的对照组B。采用免疫组化法检测各组孕妇胎盘组织中CRMP-1的表达情况,并进行各分组间的分析。结果健康孕妇胎盘组织中CRMP-1的表达量随孕周呈下降趋势,妊娠早期CRMP-1的强阳性表达量明显高于妊娠晚期 ...
袁银花, 冯双苗, 张化莲
doaj  

Placental biomarker and fetoplacental Doppler abnormalities are strongly associated with placental pathology in pregnancies with small‐for‐gestational‐age fetus: prospective study

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 6, Page 749-760, June 2025.
ABSTRACT Objective Placental dysfunction can result in small‐for‐gestational age (SGA) or fetal growth restriction (FGR). The aim of this prospective cohort study was to assess the association of the cerebroplacental ratio (CPR) and other more conventional fetoplacental Doppler indices, circulating placental growth factor (PlGF) levels and soluble fms ...
J. Hong   +6 more
wiley   +1 more source

子痫前期对围生儿的影响

open access: yesZhongguo shiyan zhenduanxue, 2007
目的探讨子痫前期对围生儿的影响。方法对2003年7月至2005年12月在我院分娩的229例子痫前期围生儿情况与随机抽取同期住院分娩的230例正常孕妇的围生儿情况进行回顾性分析。结果子痫前期早产儿、小于胎龄儿、新生儿窒息发生率及围生儿死亡率高于正常孕妇 ...
孙波, 赵艳晖, 张炜阳, 吴富菊
doaj  

Screening for pre‐eclampsia using pregnancy‐associated plasma protein‐A or placental growth factor measurements in blood samples collected at 8–14 weeks' gestation

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 5, Page 567-574, May 2025.
ABSTRACT Objectives To assess the value of pregnancy‐associated plasma protein‐A (PAPP‐A) in screening for preterm pre‐eclampsia (PE) (delivery < 37 weeks' gestation) measured in maternal blood samples collected before 11 weeks, and to compare the screening performance of PAPP‐A with that of placental growth factor (PlGF) from blood samples collected ...
L. Rode   +21 more
wiley   +1 more source

孕妇血清妊娠相关蛋白-A及超敏C反应蛋白在子痫前期临床检测意义分析

open access: yesZhongguo shiyan zhenduanxue, 2014
目的探讨孕妇血清妊娠相关蛋白-A及超敏C反应蛋白在子痫前期的临床检测意义。方法选择我院2010年7月至2013年7月期间收治的子痫前期患者共221例,上述患者根据子痫前期严重程度分为轻度子痫前期共144例,重度子痫前期患者共77例,分别作为轻度组和重度组。同时选择在我院定期产前检测的正常孕妇50例,作为对照组。采用酶联免疫吸附实验测定血清妊娠相关蛋白A水平;采用免疫发光法测定超敏C反应蛋白水平。结果重度组和轻度组的血清超敏C反应蛋白、妊娠相关蛋白A水平分别高于对照组,差异有统计学意义 ...
邓仙桃
doaj  

N‐terminal pro B‐type natriuretic peptide as biomarker to predict pre‐eclampsia and maternal–fetal complications

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 447-455, April 2025.
ABSTRACT Objective A soluble fms‐like tyrosine kinase‐1 (sFlt‐1)‐to‐placental growth factor (PlGF) ratio cut‐off of 38 is currently considered optimal for ruling out pre‐eclampsia (PE); however, implementation of this ratio in clinical practice is limited.
M. N. Nan   +15 more
wiley   +1 more source

孕妇外周血中高甲基化RASSF1A基因检测对子痫前期早期预测价值的研究

open access: yesZhongguo shiyan zhenduanxue, 2019
目的通过分析子痫前期孕妇外周血中胎儿高甲基化RASSF1A基因含量的变化,探讨孕妇外周血中胎儿游离DNA水平在子痫前期中的预测诊断价值。方法收集子痫前期孕妇外周血样本32例,择同期孕龄健康孕妇30例为对照组,采用荧光定量PCR法检测孕妇外周血中高甲基化RASSF1A基因的含量,应用受试者工作特征曲线(ROC)评价高甲基化RASSF1A基因检测对轻度和重度子痫前期孕妇的诊断价值。结果轻度子痫前期组和重度子痫前期组孕妇血浆高甲基化RASSF1A基因的中位数倍值分别是正常妊娠孕妇的3.28倍和10.47倍 ...
冉贵萍   +6 more
doaj  

Home - About - Disclaimer - Privacy