Results 31 to 40 of about 1,008 (120)
Zhongguo shiyan zhenduanxue, 2018 目的检测早发型先兆子痫妇女胎盘中坍塌反应调节蛋白-1(CRMP-1)的表达,分析其与先兆子痫临床特点的关系。方法收集30例早发型先兆子痫、30例迟发型先兆子痫孕妇作为研究对象,另选取同时期因各种原因终止妊娠的健康孕妇60例,将其按照孕周进行匹配分别作为早发型先兆子痫的对照组A、迟发型先兆子痫的对照组B。采用免疫组化法检测各组孕妇胎盘组织中CRMP-1的表达情况,并进行各分组间的分析。结果健康孕妇胎盘组织中CRMP-1的表达量随孕周呈下降趋势,妊娠早期CRMP-1的强阳性表达量明显高于妊娠晚期 ...
袁银花, 冯双苗, 张化莲
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Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 6, Page 749-760, June 2025.ABSTRACT Objective Placental dysfunction can result in small‐for‐gestational age (SGA) or fetal growth restriction (FGR). The aim of this prospective cohort study was to assess the association of the cerebroplacental ratio (CPR) and other more conventional fetoplacental Doppler indices, circulating placental growth factor (PlGF) levels and soluble fms ...
J. Hong +6 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2007 目的探讨子痫前期对围生儿的影响。方法对2003年7月至2005年12月在我院分娩的229例子痫前期围生儿情况与随机抽取同期住院分娩的230例正常孕妇的围生儿情况进行回顾性分析。结果子痫前期早产儿、小于胎龄儿、新生儿窒息发生率及围生儿死亡率高于正常孕妇 ...
孙波, 赵艳晖, 张炜阳, 吴富菊
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Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 5, Page 567-574, May 2025.ABSTRACT Objectives To assess the value of pregnancy‐associated plasma protein‐A (PAPP‐A) in screening for preterm pre‐eclampsia (PE) (delivery < 37 weeks' gestation) measured in maternal blood samples collected before 11 weeks, and to compare the screening performance of PAPP‐A with that of placental growth factor (PlGF) from blood samples collected ...
L. Rode +21 more
wiley +1 more source
孕妇血清妊娠相关蛋白-A及超敏C反应蛋白在子痫前期临床检测意义分析
Zhongguo shiyan zhenduanxue, 2014 目的探讨孕妇血清妊娠相关蛋白-A及超敏C反应蛋白在子痫前期的临床检测意义。方法选择我院2010年7月至2013年7月期间收治的子痫前期患者共221例,上述患者根据子痫前期严重程度分为轻度子痫前期共144例,重度子痫前期患者共77例,分别作为轻度组和重度组。同时选择在我院定期产前检测的正常孕妇50例,作为对照组。采用酶联免疫吸附实验测定血清妊娠相关蛋白A水平;采用免疫发光法测定超敏C反应蛋白水平。结果重度组和轻度组的血清超敏C反应蛋白、妊娠相关蛋白A水平分别高于对照组,差异有统计学意义 ...
邓仙桃
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Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 4, Page 447-455, April 2025.ABSTRACT Objective A soluble fms‐like tyrosine kinase‐1 (sFlt‐1)‐to‐placental growth factor (PlGF) ratio cut‐off of 38 is currently considered optimal for ruling out pre‐eclampsia (PE); however, implementation of this ratio in clinical practice is limited.
M. N. Nan +15 more
wiley +1 more source
孕妇外周血中高甲基化RASSF1A基因检测对子痫前期早期预测价值的研究
Zhongguo shiyan zhenduanxue, 2019 目的通过分析子痫前期孕妇外周血中胎儿高甲基化RASSF1A基因含量的变化,探讨孕妇外周血中胎儿游离DNA水平在子痫前期中的预测诊断价值。方法收集子痫前期孕妇外周血样本32例,择同期孕龄健康孕妇30例为对照组,采用荧光定量PCR法检测孕妇外周血中高甲基化RASSF1A基因的含量,应用受试者工作特征曲线(ROC)评价高甲基化RASSF1A基因检测对轻度和重度子痫前期孕妇的诊断价值。结果轻度子痫前期组和重度子痫前期组孕妇血浆高甲基化RASSF1A基因的中位数倍值分别是正常妊娠孕妇的3.28倍和10.47倍 ...
冉贵萍 +6 more
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Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 3, Page 303-310, March 2025.ABSTRACT Objective Globally, one in four pregnant women is classified as overweight or obese, based on their prepregnancy body mass index (BMI). Obese pregnant women are at increased risk of adverse pregnancy outcomes and long‐term cardiovascular disease that occurs earlier in life.
M. Charakida +6 more
wiley +1 more source
Prediction of pre‐eclampsia using maternal hemodynamic parameters at 12 + 0 to 15 + 6 weeks
Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 2, Page 173-182, February 2025.ABSTRACT Objectives To compare the maternal hemodynamic profile at 12 + 0 to 15 + 6 weeks' gestation in women who subsequently developed pre‐eclampsia (PE) and those who did not, and to assess the screening performance of maternal hemodynamic parameters for PE in combination with the Fetal Medicine Foundation (FMF) triple test, including maternal ...
X. Wang +9 more
wiley +1 more source
胎盘GM-CSF及蜕膜基板中滋养细胞、巨噬细胞与子痫前期的关系
Zhongshan Daxue xuebao. Yixue kexue ban, 2006 [目的]探讨胎盘粒-巨噬细胞集落刺激因子（GM-CSF）、蜕膜基板中滋养细胞、巨噬细胞的变化与子痫前期的相关性.[方法]采用免疫组化的方法检测24例子痫前期孕妇胎盘组织中的GM-CSF的相对含量以及蜕膜基板中滋养细胞、巨噬细胞的变化,并以22例正常初孕妇为对照.[结果]子痫前期组胎盘组织GM-CSF水平（11.06±1.83）明显高于对照组（5.45±1.11）,P＜0.001.子痫前期组蜕膜基板滋养细胞数（70.25±21.07）明显低于对照组（92.73±17.46）,P＜0.001 ...
王冰, 黄顺英, 蔡坚
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