FIS1 mRNA、HPV E6/E7 mRNA表达水平与宫颈病变严重程度的关系研究
Zhongguo shiyan zhenduanxue, 2023 目的 研究线粒体分裂蛋白1(FIS1)mRNA、人乳头瘤病毒(HPV)E6/E7 mRNA表达水平与宫颈病变严重程度的关系。方法 收集张家口市妇幼保健院2021年1月-2021年7月行宫颈癌筛查的5666例标本，经宫颈液基薄层细胞学检查(TCT)诊断285例不典型鳞状细胞(ASC)、183例鳞状上皮内低度病变(LSIL)、98例鳞状上皮内高度病变(HSIL)、10例宫颈癌；经病理活检诊断356例未明确诊断意义的不典型鳞状上皮细胞(ASCUS)、218例宫颈上皮内瘤样病变(CIN)Ⅰ级、42例CINⅡ级 ...
武振宇
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Value of machine learning model based on MRI radiomics in predicting histological grade of cervical squamous cell carcinoma [PDF]
Objective To explore the predictive value of different machine learning models based on MRI radiomics combined with clinical features for histological grade of cervical squamous cell carcinoma. Methods Clinical data of 150 patients with cervical squamous
Wang Hezhen, Bian Fang, Tong Yujie, Duan Yanan, Zhai Dongzhi
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Evaluation value of combined detection of four serological indicators for the effect of concurrent chemoradiotherapy in cervical cancer [PDF]
Objective To explore the predictive value of combined detection of serum suppressor of cytokine signal 1 (SOCS1), matrix metalloproteinase-9 (MMP-9), squamous cell carcinoma antigen (SCCA), and thymidine kinase 1 (TK1) for clinical efficacy in cervical ...
LUO Qingbin, ZHENG Danning, WU Di
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Clinical significance of Twist, Bmi-1 and E-cadherin expression in Cervical Intraepithelial Neoplasia and Early Stage Cervical Cancer [PDF]
, 2015 目的：研究Twist/Bmi-1/E-cadherin蛋白在早期宫颈癌组织、宫颈上皮内瘤变（CIN）组织与正常宫颈组织中的表达水平，探讨Twist/Bmi-1/E-cadherin在早期宫颈癌不同病变组织中表达的生物学意义，对宫颈癌患者预后的影响以及这三者之间的相关性。 方法：收集2009年7月—2013年10月在厦门大学附属中山医院手术切除的64例宫颈癌，41例CIN组织，12例正常宫颈组织石蜡标本，运用Elivision免疫组化法检测Twist/Bmi-1/E-cadherin在宫颈癌组织 ...
丁娅妮
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Significances of detection of 24 genetypes of HPV in diagnosis of cervical lesions [PDF]
, 2015 目的:应用基因芯片技术检测宫颈疾病中人乳头瘤病毒(HPV)的基因型及分布特点,并探讨其临床意义。方法:应用基因芯片技术,对经病理确诊200例宫颈癌前病变及宫颈癌的患者进行24种HPV基因型检测,分析HPV基因型与宫颈病变的相关性。结果:1总共检出24种HPV基因型中的20种基因型,居前5位是HPV16、HPV18、HPV58、HPV59、HPV54,其中高危型HPV占83.9%,以HPV16、HPV18、HPV58多见;低危型占16.1%,以HPV54、HPV6、HPV70多见;2慢性宫颈炎 ...
唐忠辉 +4 more
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Comparison of characteristics of cervical cancer screening history between cervical adenocarcinoma and cervical squamous cell carcinoma [PDF]
Objective To comparatively analyze the characteristics of cervical cancer screening history between patients with cervical adenocarcinoma and cervical squamous cell carcinoma， and to preliminarily evaluate the efficacy of cervical cancer screening for ...
Ye Minjuan, Li Jing, Chen Zifei, He Junxian, Chen Lifa, Zhang Yu
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MMP-2与TIMP-2在宫颈鳞状细胞癌组织中的表达及临床意义
Zhongguo shiyan zhenduanxue, 2013 目的检测基质金属蛋白酶-2（MMP-2）与基质金属蛋白酶抑制剂-2（TIMP-2）在宫颈鳞状细胞癌组织中的表达,探讨宫颈鳞状细胞癌发展与临床分期及淋巴结转移中的意义。方法应用免疫组化法和图像分析方法检测MMP-2与TIMP-2在正常宫颈、宫颈上皮内瘤变（CIN）及宫颈鳞癌组织中的表达情况,并对临床病理特征进行对比分析。结果 MMP-2在正常宫颈、CIN、宫颈鳞癌组织中表达阳性率逐渐增高 ...
朱丹 +5 more
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Mirk/Dyrk1b在上皮性卵巢癌组织中的表达及意义 [PDF]
, 2011 目的:探讨Mirk/Dryk1b(Minibrain-related kinase/Dual specificity tyrosine-phosphorylation-regulated kinase1B)在卵巢组织中的表达及其临床意义。方法:利用免疫组化检测Mirk/Dyrk1b在30例上皮性卵巢癌、20例上皮性卵巢囊腺瘤、10例正常卵巢组织中的表达。结果:Dyrk1b在上皮性卵巢癌中的表达明显高于上皮性卵巢囊腺瘤及正常卵巢组织(P0.05)。结论:Dyrk1b在上皮性卵巢癌中高表达 ...
廖洪锋 +7 more
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Correlation Between Peripheral Blood Inflammatory Markers and 18F-FDG PET/CT Metabolic Parameters in Tumors [PDF]
Inflammatory markers in peripheral blood, such as neutrophil-lymphocyte ratio and platelet-lymphocyte ratio, can reflect the reactive hyperplasia of inflammatory cells in tumors.
Dasheng QIU, Yilin TONG
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Zhongguo shiyan zhenduanxue, 2005 目的研究CyclinD1和P27蛋白在宫颈鳞状细胞癌发生、发展中的作用及其与宫颈鳞癌临床病理特征的关系。方法应用SP免疫组化法检测40例宫颈鳞癌,25例宫颈不典型增生组织中CyclinD1和P27蛋白的表达,取正常宫颈组织10例作为对照。结果CyclinD1在宫颈鳞癌中呈高表达,P27在宫颈鳞癌中呈低表达,与对照组均有组间差异 ...
何凯 +5 more
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