Evaluation value of combined detection of four serological indicators for the effect of concurrent chemoradiotherapy in cervical cancer [PDF]
Objective To explore the predictive value of combined detection of serum suppressor of cytokine signal 1 (SOCS1), matrix metalloproteinase-9 (MMP-9), squamous cell carcinoma antigen (SCCA), and thymidine kinase 1 (TK1) for clinical efficacy in cervical ...
LUO Qingbin, ZHENG Danning, WU Di
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Clinical significance of Twist, Bmi-1 and E-cadherin expression in Cervical Intraepithelial Neoplasia and Early Stage Cervical Cancer [PDF]
, 2015 目的：研究Twist/Bmi-1/E-cadherin蛋白在早期宫颈癌组织、宫颈上皮内瘤变（CIN）组织与正常宫颈组织中的表达水平，探讨Twist/Bmi-1/E-cadherin在早期宫颈癌不同病变组织中表达的生物学意义，对宫颈癌患者预后的影响以及这三者之间的相关性。 方法：收集2009年7月—2013年10月在厦门大学附属中山医院手术切除的64例宫颈癌，41例CIN组织，12例正常宫颈组织石蜡标本，运用Elivision免疫组化法检测Twist/Bmi-1/E-cadherin在宫颈癌组织 ...
丁娅妮
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Significances of detection of 24 genetypes of HPV in diagnosis of cervical lesions [PDF]
, 2015 目的:应用基因芯片技术检测宫颈疾病中人乳头瘤病毒(HPV)的基因型及分布特点,并探讨其临床意义。方法:应用基因芯片技术,对经病理确诊200例宫颈癌前病变及宫颈癌的患者进行24种HPV基因型检测,分析HPV基因型与宫颈病变的相关性。结果:1总共检出24种HPV基因型中的20种基因型,居前5位是HPV16、HPV18、HPV58、HPV59、HPV54,其中高危型HPV占83.9%,以HPV16、HPV18、HPV58多见;低危型占16.1%,以HPV54、HPV6、HPV70多见;2慢性宫颈炎 ...
唐忠辉 +4 more
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Correlation Between Peripheral Blood Inflammatory Markers and 18F-FDG PET/CT Metabolic Parameters in Tumors [PDF]
Inflammatory markers in peripheral blood, such as neutrophil-lymphocyte ratio and platelet-lymphocyte ratio, can reflect the reactive hyperplasia of inflammatory cells in tumors.
Dasheng QIU, Yilin TONG
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Mirk/Dyrk1b在上皮性卵巢癌组织中的表达及意义 [PDF]
, 2011 目的:探讨Mirk/Dryk1b(Minibrain-related kinase/Dual specificity tyrosine-phosphorylation-regulated kinase1B)在卵巢组织中的表达及其临床意义。方法:利用免疫组化检测Mirk/Dyrk1b在30例上皮性卵巢癌、20例上皮性卵巢囊腺瘤、10例正常卵巢组织中的表达。结果:Dyrk1b在上皮性卵巢癌中的表达明显高于上皮性卵巢囊腺瘤及正常卵巢组织(P0.05)。结论:Dyrk1b在上皮性卵巢癌中高表达 ...
廖洪锋 +7 more
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Comparison of characteristics of cervical cancer screening history between cervical adenocarcinoma and cervical squamous cell carcinoma [PDF]
Objective To comparatively analyze the characteristics of cervical cancer screening history between patients with cervical adenocarcinoma and cervical squamous cell carcinoma， and to preliminarily evaluate the efficacy of cervical cancer screening for ...
Ye Minjuan, Li Jing, Chen Zifei, He Junxian, Chen Lifa, Zhang Yu
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Application of a new type of cell wax block vertical embedding technique in the pathological diagnosis of serous cavity effusion [PDF]
Objective To introduce the application of a new type of cell wax block vertical embedding technique in the pathological diagnosis of serous cavity effusion.
CHEN Jia +5 more
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Research progress on medical imaging-based artificial intelligence in precision diagnosis and treatment of pancreatic cancer [PDF]
Pancreatic cancer is a highly malignant tumor of the digestive tract， and its precision diagnosis and treatment is a major challenge in clinical practice.
Zhu Lubing, Wang Jianhua
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目的探讨卵巢组织冻存及自体移植手术保护子宫颈癌患者生育力与卵巢内分泌功能的疗效。方法对1例26岁子宫颈癌ⅡA1期患者在癌症手术过程中进行卵巢组织取材、冻存，待其癌症完全缓解后进行冻存卵巢组织自体移植手术，随访监测患者的绝经相关症状、激素水平及卵泡发育情况。结果卵巢组织移植第6个月卵泡刺激素降低至6.60 U/L，雌二醇由＜10.00 ng/L升高至89.00 ng/L。移植第10个月，B超监测到移植卵巢组织有卵泡发育且能完成生理排卵功能。移植第15个月，卵泡刺激素维持在7.24 U/L ...
吴楚玲 +7 more
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人乳头瘤病毒18型病毒样颗粒在大肠杆菌中的表达及免疫原性分析 [PDF]
, 2009 利用大肠杆菌表达系统可溶性表达人乳头瘤病毒18型(HPV18)L1蛋白,经过纯化和重组装过程获得HPV18病毒样颗粒(VLPs),研究其免疫原性和诱发中和抗体生成的水平。首先,提取HPV18的基因组DNA,通过PCR扩增获得HPV18 L1基因片段,将其插入pTrxFus表达载体,在大肠杆菌中可溶性表达HPV18 L1蛋白;其次,通过硫酸铵沉淀、离子交换层析和疏水相互作用层析获得高纯度的HPV18 L1蛋白,而后透析去除预先加入的还原剂DTT,使HPV18 L1蛋白自发组装成VLPs;最后 ...
吴婷 +9 more
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