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一例儿童Leigh综合征

Zhongguo shiyan zhenduanxue, 2019
Leigh综合征（Leigh Syndrome,LS）又称亚急性坏死性脑脊髓病（SNEM）,是一种罕见的、由遗传基因缺陷导致的以脑和肌肉受累为主的线粒体疾病。其特征性表现为肌无力、慢性进行性眼外肌麻痹、智能障碍、共济失调、发作性肌阵挛、视神经病变等。典型影像学MRI表现为基底节区及脑干对称性异常信号。据目前报道,约48%至80%的患者在1岁以内发病[1,2],幼儿期发病者少见。另外,近年国外研究显示,线粒体疾病患者中仅约7-10%可检测出线粒体DNA（mitochondrial DNA,mtDNA）变异[
赵宏霞, 王杏, 梁奕洋, 刘海英, 吴春远   +4 more
doaj  

基于稀疏引导IEWT‑MOMEDA的行星齿轮箱微弱故障检测

Zhendong Ceshi yu Zhenduan
行星齿轮箱出现早期故障时，由于工业环境的背景噪声干扰和故障冲击在复杂传递路径中衰减，其微弱故障特征难以有效提取和识别。针对此问题，提出了稀疏引导的改进经验小波变换（improved empirical wavelet transform，简称IEWT）结合多点最优最小熵解卷积（multipoint optimal minimum entropy deconvolution adjusted，简称MOMEDA）的微弱故障特征提取方法。首先，提出了一种新的故障综合指标（fault composite ...
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[Detection of neurofibroma combining radiomics and ensemble learning]. [PDF]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
Liu Y, Wencheng D, Wang Y, Wang Y, Yan Y, Gan K, Pan T.   +6 more
europepmc   +1 more source

[Determination of five photoinitiators including 2，4，6-trimethylbenzoyl diphenyl phosphine oxide in gel nail polish by high performance liquid chromatography]. [PDF]

Se Pu
Gong X, Sun J, Li XX, Feng YL.
europepmc   +1 more source

[Determination of caffeine and taurine in electronic cigarette oil by high performance liquid chromatography- tandem mass spectrometry]. [PDF]

Se Pu
Sun X, Chang QZ, Wang C, Shao WH, Feng F.   +4 more
europepmc   +1 more source

[Electroencephalographic assessment of the relationship between frontal alpha asymmetry and emotion dysregulation in children with attention deficit hyperactivity disorder]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Chen L, Zhao LL, Wu XC, Li HY, Zhang WW.
europepmc   +1 more source

[Determination of tetracyclines in animal muscle tissues by ultra performance liquid chromatography- tandem mass spectrometry]. [PDF]

Se Pu
Chu K, Li JH, Wang QQ, Li XT, Wu S, Chen C.   +5 more
europepmc   +1 more source

[Simultaneous determination of vitamins K₁ and K₂ in cosmetics by QuEChERS-high performance liquid chromatography and verification by high performance liquid chromatography-tandem mass spectrometry]. [PDF]

Se Pu
Sun Q, Chen CX.
europepmc   +1 more source

[Indicative effect of indocyanine green-near-infrared fluorescence imaging in the thickness of necrotic dermal tissue in porcine burn wounds]. [PDF]

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi
Zhang YS, Pan X, Ge YL, Yue JC, Song YX, Song WY, Zhao R.   +6 more
europepmc   +1 more source

[Determination of genotoxic impurity in the bulk drug of crizotinib by high performance liquid chromatography-electrospray ionization tandem mass spectrometry]. [PDF]

Se Pu
Zhan XB, Qin Y, Yan Y, Zhou J, Zhao LS.
europepmc   +1 more source